Publications
Found 12 results
Filters: Author is Kobilka, Brian K [Clear All Filters]
"Nanobodies to Study G Protein-Coupled Receptor Structure and Function.",
Annu Rev Pharmacol Toxicol, vol. 57, pp. 19-37, 2017 01 06.
"Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.",
Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.
"Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.",
Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
"Propagation of conformational changes during μ-opioid receptor activation.",
Nature, vol. 524, issue 7565, pp. 375-8, 2015 Aug 20.
"Structural insights into µ-opioid receptor activation.",
Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.
"A general protocol for the generation of Nanobodies for structural biology.",
Nat Protoc, vol. 9, issue 3, pp. 674-93, 2014 Mar.
"Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.",
Mol Pharmacol, vol. 85, issue 3, pp. 472-81, 2014 Mar.
"Activation and allosteric modulation of a muscarinic acetylcholine receptor.",
Nature, vol. 504, issue 7478, pp. 101-6, 2013 Dec 05.
"Crystal structure of the β2 adrenergic receptor-Gs protein complex.",
Nature, vol. 477, issue 7366, pp. 549-55, 2011 Sep 29.
"Nanobody stabilization of G protein-coupled receptor conformational states.",
Curr Opin Struct Biol, vol. 21, issue 4, pp. 567-72, 2011 Aug.
"Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex.",
Proc Natl Acad Sci U S A, vol. 108, issue 38, pp. 16086-91, 2011 Sep 20.
"Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.",
Nature, vol. 469, issue 7329, pp. 175-80, 2011 Jan 13.