Publications

Found 23 results
Filters: Author is Guharoy, Mainak  [Clear All Filters]
2017
Boeynaems, S., Bogaert E., Kovacs D., Konijnenberg A., Timmerman E., Volkov A., Guharoy M., De Decker M., Jaspers T., Ryan V. H., et al., "Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.", Mol Cell, vol. 65, issue 6, pp. 1044-1055.e5, 2017 Mar 16.
2016
Guharoy, M., Bhowmick P., and Tompa P., "Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.", J Biol Chem, vol. 291, issue 13, pp. 6723-31, 2016 Mar 25.
Braten, O., Livneh I., Ziv T., Admon A., Kehat I., Caspi L. H., Gonen H., Bercovich B., Godzik A., Jahandideh S., et al., "Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.", Proc Natl Acad Sci U S A, vol. 113, issue 32, pp. E4639-47, 2016 Aug 09.
Guharoy, M., Bhowmick P., Sallam M., and Tompa P., "Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.", Nat Commun, vol. 7, pp. 10239, 2016 Jan 06.
2015
Bhowmick, P., Guharoy M., and Tompa P., "Bioinformatics Approaches for Predicting Disordered Protein Motifs.", Adv Exp Med Biol, vol. 870, pp. 291-318, 2015.
Varadi, M., Vranken W., Guharoy M., and Tompa P., "Computational approaches for inferring the functions of intrinsically disordered proteins.", Front Mol Biosci, vol. 2, pp. 45, 2015.
Varadi, M., Guharoy M., Zsolyomi F., and Tompa P., "DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder.", BMC Bioinformatics, vol. 16, pp. 153, 2015 May 13.
Borysik, A. J., Kovacs D., Guharoy M., and Tompa P., "Ensemble Methods Enable a New Definition for the Solution to Gas-Phase Transfer of Intrinsically Disordered Proteins.", J Am Chem Soc, vol. 137, issue 43, pp. 13807-17, 2015 Nov 04.
Varadi, M., Zsolyomi F., Guharoy M., and Tompa P., "Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins.", PLoS One, vol. 10, issue 10, pp. e0139731, 2015.
Guharoy, M., Pauwels K., and Tompa P., "SnapShot: Intrinsic Structural Disorder.", Cell, vol. 161, issue 5, pp. 1230-1230.e1, 2015 May 21.
2013
Bhowmick, P., Pancsa R., Guharoy M., and Tompa P., "Functional diversity and structural disorder in the human ubiquitination pathway.", PLoS One, vol. 8, issue 5, pp. e65443, 2013.
Guharoy, M., Szabo B., Martos S. Contreras, Kosol S., and Tompa P., "Intrinsic structural disorder in cytoskeletal proteins.", Cytoskeleton (Hoboken), vol. 70, issue 10, pp. 550-71, 2013 Oct.
Chakravarty, D., Guharoy M., Robert C. H., Chakrabarti P., and Janin J., "Reassessing buried surface areas in protein-protein complexes.", Protein Sci, vol. 22, issue 10, pp. 1453-7, 2013 Oct.
2012
Dey, S., Pal A., Guharoy M., Sonavane S., and Chakrabarti P., "Characterization and prediction of the binding site in DNA-binding proteins: improvement of accuracy by combining residue composition, evolutionary conservation and structural parameters.", Nucleic Acids Res, vol. 40, issue 15, pp. 7150-61, 2012 Aug.
2011
Fleishman, S. J., Whitehead T. A., Strauch E-M., Corn J. E., Qin S., Zhou H-X., Mitchell J. C., Demerdash O. N. A., Takeda-Shitaka M., Terashi G., et al., "Community-wide assessment of protein-interface modeling suggests improvements to design methodology.", J Mol Biol, vol. 414, issue 2, pp. 289-302, 2011 Nov 25.
Guharoy, M., Pal A., Dasgupta M., and Chakrabarti P., "PRICE (PRotein Interface Conservation and Energetics): a server for the analysis of protein-protein interfaces.", J Struct Funct Genomics, vol. 12, issue 1, pp. 33-41, 2011 Mar.
2010
Guharoy, M., and Chakrabarti P., "Conserved residue clusters at protein-protein interfaces and their use in binding site identification.", BMC Bioinformatics, vol. 11, pp. 286, 2010.
Guharoy, M., Janin J., and Robert C. H., "Side-chain rotamer transitions at protein-protein interfaces.", Proteins, vol. 78, issue 15, pp. 3219-25, 2010 Nov 15.
2009
Biswas, S., Guharoy M., and Chakrabarti P., "Dissection, residue conservation, and structural classification of protein-DNA interfaces.", Proteins, vol. 74, issue 3, pp. 643-54, 2009 Feb 15.
Guharoy, M., and Chakrabarti P., "Empirical estimation of the energetic contribution of individual interface residues in structures of protein-protein complexes.", J Comput Aided Mol Des, vol. 23, issue 9, pp. 645-54, 2009 Sep.
2008
Biswas, S., Guharoy M., and Chakrabarti P., "Structural segments and residue propensities in protein-RNA interfaces: comparison with protein-protein and protein-DNA complexes.", Bioinformation, vol. 2, issue 10, pp. 422-7, 2008.
2007
Guharoy, M., and Chakrabarti P., "Secondary structure based analysis and classification of biological interfaces: identification of binding motifs in protein-protein interactions.", Bioinformatics, vol. 23, issue 15, pp. 1909-18, 2007 Aug 1.
2005
Guharoy, M., and Chakrabarti P., "Conservation and relative importance of residues across protein-protein interfaces.", Proc Natl Acad Sci U S A, vol. 102, issue 43, pp. 15447-52, 2005 Oct 25.