Publications

Found 120 results
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2016
Vandervelde, A., Loris R., Danckaert J., and Gelens L., "Computational Methods to Model Persistence.", Methods Mol Biol, vol. 1333, pp. 207-40, 2016.
2014
Sterckx, Y. G. J., Haesaerts S., Van Melderen L., and Loris R., "Crystallization and preliminary X-ray analysis of two variants of the Escherichia coli O157 ParE2-PaaA2 toxin-antitoxin complex.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 9, pp. 1284-91, 2014 Sep.
Loris, R., and Garcia-Pino A., "Disorder- and dynamics-based regulatory mechanisms in toxin-antitoxin modules.", Chem Rev, vol. 114, issue 13, pp. 6933-47, 2014 Jul 09.
Garcia-Pino, A., Zenkin N., and Loris R., "The many faces of Fic: structural and functional aspects of Fic enzymes.", Trends Biochem Sci, vol. 39, issue 3, pp. 121-9, 2014 Mar.
Bethuyne, J., De Gieter S., Zwaenepoel O., Garcia-Pino A., Durinck K., Verhelle A., Hassanzadeh-Ghassabeh G., Speleman F., Loris R., and Gettemans J., "A nanobody modulates the p53 transcriptional program without perturbing its functional architecture.", Nucleic Acids Res, vol. 42, issue 20, pp. 12928-38, 2014 Nov 10.
Fislage, M., Brosens E., Deyaert E., Spilotros A., Pardon E., Loris R., Steyaert J., Garcia-Pino A., and Versées W., "SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization.", Nucleic Acids Res, vol. 42, issue 9, pp. 5978-92, 2014 May.
Sterckx, Y. G. J., Volkov A., Vranken W. F., Kragelj J., Jensen M. Ringkjøbi, Buts L., Garcia-Pino A., Jové T., Van Melderen L., Blackledge M., et al., "Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2.", Structure, vol. 22, issue 6, pp. 854-65, 2014 Jun 10.
Zorzini, V., Buts L., Sleutel M., Garcia-Pino A., Talavera A., Haesaerts S., De Greve H., Cheung A., van Nuland N. A. J., and Loris R., "Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics.", Nucleic Acids Res, vol. 42, issue 10, pp. 6709-25, 2014 Jun.
2013
De Gieter, S., Loris R., van Nuland N. A. J., and Garcia-Pino A., "(1)H, (13)C, and (15)N backbone and side-chain chemical shift assignment of the toxin Doc in the unbound state.", Biomol NMR Assign, 2013 Feb 19.
Ghequire, M. G. K., De Canck E., Wattiau P., Van Winge I., Loris R., Coenye T., and De Mot R., "Antibacterial activity of a lectin-like Burkholderia cenocepacia protein.", Microbiologyopen, vol. 2, issue 4, pp. 566-75, 2013 Aug.
Hadži, S., Garcia-Pino A., Martinez-Rodriguez S., Verschueren K., Christensen-Dalsgaard M., Gerdes K., Lah J., and Loris R., "Crystallization of the HigBA2 toxin-antitoxin complex from Vibrio cholerae.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 9, pp. 1052-9, 2013 Sep.
Drobnak, I., De Jonge N., Haesaerts S., Vesnaver G., Loris R., and Lah J., "Energetic basis of uncoupling folding from binding for an intrinsically disordered protein.", J Am Chem Soc, vol. 135, issue 4, pp. 1288-94, 2013 Jan 30.
Castro-Roa, D., Garcia-Pino A., De Gieter S., van Nuland N. A. J., Loris R., and Zenkin N., "The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu.", Nat Chem Biol, vol. 9, issue 12, pp. 811-7, 2013 Dec.
Gelens, L., Hill L., Vandervelde A., Danckaert J., and Loris R., "A general model for toxin-antitoxin module dynamics can explain persister cell formation in E. coli.", PLoS Comput Biol, vol. 9, issue 8, pp. e1003190, 2013.
Vuchelen, A., Pardon E., Steyaert J., Gamain B., Loris R., van Nuland N. A. J., and Ramboarina S., "Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein. Corrigendum.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 11, pp. 1312, 2013 Nov.
Vuchelen, A., Pardon E., Steyaert J., Gamain B., Loris R., van Nuland N. A. J., and Ramboarina S., "Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 3, pp. 270-4, 2013 Mar 1.
Ghequire, M. G. K., Garcia-Pino A., Lebbe E. K. M., Spaepen S., Loris R., and De Mot R., "Structural determinants for activity and specificity of the bacterial toxin LlpA.", PLoS Pathog, vol. 9, issue 2, pp. e1003199, 2013 Feb.
2012
De Jonge, N., Simic M., Buts L., Haesaerts S., Roelants K., Garcia-Pino A., Sterckx Y., De Greve H., Lah J., and Loris R., "Alternative interactions define gyrase specificity in the CcdB family.", Mol Microbiol, vol. 84, issue 5, pp. 965-78, 2012 Jun.
Ghequire, M. G. K., Loris R., and De Mot R., "MMBL proteins: from lectin to bacteriocin.", Biochem Soc Trans, vol. 40, issue 6, pp. 1553-9, 2012 Dec 1.
Martinez-Rodriguez, S., Garcia-Pino A., Heras-Vázquez F. Javier Las, Clemente-Jiménez J. María, Rodríguez-Vico F., García-Ruiz J. M., Loris R., and Gavira J. Antonio, "Mutational and structural analysis of L-N-carbamoylase reveals new insights into a peptidase M20/M25/M40 family member.", J Bacteriol, vol. 194, issue 21, pp. 5759-68, 2012 Nov.
Sterckx, Y., Garcia-Pino A., Haesaerts S., Jové T., Geerts L., Sakellaris V., Van Melderen L., and Loris R., "The ParE2-PaaA2 toxin-antitoxin complex from Escherichia coli O157 forms a heterodocecamer in solution and in the crystal.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 68, issue Pt 6, pp. 724-9, 2012 Jun 1.
Ghequire, M. G. K., Li W., Proost P., Loris R., and De Mot R., "Plant lectin-like antibacterial proteins from phytopathogens Pseudomonas syringae and Xanthomonas citri.", Environ Microbiol Rep, vol. 4, issue 4, pp. 373-80, 2012 Aug.
2011
Zorzini, V., Haesaerts S., Cheung A., Loris R., and van Nuland N. A. J., "1H, 13C, and 15N backbone and side-chain chemical shift assignment of the staphylococcal MazF mRNA interferase.", Biomol NMR Assign, vol. 5, issue 2, pp. 157-60, 2011 Oct.
Zorzini, V., Haesaerts S., Donegan N. P., Fu Z., Cheung A. L., van Nuland N. A. J., and Loris R., "Crystallization of the Staphylococcus aureus MazF mRNA interferase.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 67, issue Pt 3, pp. 386-9, 2011 Mar 1.
2010
Garcia-Pino, A., Balasubramanian S., Wyns L., Gazit E., De Greve H., Magnuson R. D., Charlier D., van Nuland N. A. J., and Loris R., "Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity.", Cell, vol. 142, issue 1, pp. 101-11, 2010 Jul 9.

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