Publications

Found 190 results
Filters: Keyword is Crystallography, X-Ray  [Clear All Filters]
2017
Rosado, L. Astolfi, Wahni K., Degiacomi G., Pedre B., Young D., de la Rubia A. G., Boldrin F., Martens E., Marcos-Pascual L., Sancho-Vaello E., et al., "The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.", J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 Aug 11.
Hadži, S., Garcia-Pino A., Haesaerts S., Jurenas D., Gerdes K., Lah J., and Loris R., "Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.", Nucleic Acids Res, vol. 45, issue 8, pp. 4972-4983, 2017 May 05.
Gkekas, S., Singh R. Kumar, Shkumatov A. V., Messens J., Fauvart M., Verstraeten N., Michiels J., and Versées W., "Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence.", J Biol Chem, vol. 292, issue 14, pp. 5871-5883, 2017 Apr 07.
Singh, R. Kumar, Steyaert J., and Versées W., "Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis.", Protein Sci, vol. 26, issue 5, pp. 985-996, 2017 May.
Miller, P. S., Scott S., Masiulis S., De Colibus L., Pardon E., Steyaert J., and A Aricescu R., "Structural basis for GABAA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
2016
Staus, D. P., Strachan R. T., Manglik A., Pani B., Kahsai A. W., Kim T. Hun, Wingler L. M., Ahn S., Chatterjee A., Masoudi A., et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
Fischer, B., Lüthy K., Paesmans J., De Koninck C., Maes I., Swerts J., Kuenen S., Uytterhoeven V., Verstreken P., and Versées W., "Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.", Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
Van Laer, B., Roovers M., Wauters L., Kasprzak J. M., Dyzma M., Deyaert E., Singh R. Kumar, Feller A., Bujnicki J. M., Droogmans L., et al., "Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.", Nucleic Acids Res, vol. 44, issue 2, pp. 940-53, 2016 Jan 29.
Zorzini, V., Mernik A., Lah J., Sterckx Y. G. J., De Jonge N., Garcia-Pino A., De Greve H., Versées W., and Loris R., "Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.", J Biol Chem, vol. 291, issue 21, pp. 10950-60, 2016 May 20.
Sterckx, Y. G. - J., Jové T., Shkumatov A. V., Garcia-Pino A., Geerts L., De Kerpel M., Lah J., De Greve H., Van Melderen L., and Loris R., "A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.", J Mol Biol, vol. 428, issue 8, pp. 1589-603, 2016 Apr 24.
2015
Newman, J. A., Savitsky P., Allerston C. K., Bizard A. H., Özer Ö., Sarlós K., Liu Y., Pardon E., Steyaert J., Hickson I. D., et al., "Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.", Nucleic Acids Res, vol. 43, issue 10, pp. 5221-35, 2015 May 26.
Cho, K. Joon, Schepens B., Moonens K., Deng L., Fiers W., Remaut H., and Saelens X., "Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody.", J Virol, vol. 90, issue 1, pp. 611-5, 2015 Oct 14.
Haesaerts, S., Buitrago J. Alexander, Loris R., Baeyens-Volant D., and Azarkan M., "Crystallization and preliminary X-ray analysis of four cysteine proteases from Ficus carica latex.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 4, pp. 459-65, 2015 Apr.
Hadži, S., Garcia-Pino A., Gerdes K., Lah J., and Loris R., "Crystallization of two operator complexes from the Vibrio cholerae HigBA2 toxin-antitoxin module.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 2, pp. 226-33, 2015 Feb.
Haynes, C. L. F., Ameloot P., Remaut H., Callewaert N., Sterckx Y. G. J., and Magez S., "Production, purification and crystallization of a trans-sialidase from Trypanosoma vivax.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 5, pp. 577-85, 2015 May.
Coppens, F., Iyyathurai J., Ruer S., Fioravanti A., Taganna J., Vereecke L., De Greve H., and Remaut H., "Structural and adhesive properties of the long polar fimbriae protein LpfD from adherent-invasive Escherichia coli.", Acta Crystallogr D Biol Crystallogr, vol. 71, issue Pt 8, pp. 1615-26, 2015 Aug.
Moonens, K., Van den Broeck I., De Kerpel M., Deboeck F., Raymaekers H., Remaut H., and De Greve H., "Structural and functional insight into the carbohydrate receptor binding of F4 fimbriae-producing enterotoxigenic Escherichia coli.", J Biol Chem, vol. 290, issue 13, pp. 8409-19, 2015 Mar 27.
Moonens, K., Van den Broeck I., Okello E., Pardon E., De Kerpel M., Remaut H., and De Greve H., "Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.", Vet Res, vol. 46, pp. 14, 2015 Feb 24.
Huculeci, R., Garcia-Pino A., Buts L., Lenaerts T., and van Nuland N., "Structural insights into the intertwined dimer of fyn SH2.", Protein Sci, vol. 24, issue 12, pp. 1964-78, 2015 Dec.
Huang, W., Manglik A., Venkatakrishnan A. J., Laeremans T., Feinberg E. N., Sanborn A. L., Kato H. E., Livingston K. E., Thorsen T. S., Kling R. C., et al., "Structural insights into µ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.
Rostislavleva, K., Soler N., Ohashi Y., Zhang L., Pardon E., Burke J. E., Masson G. R., Johnson C., Steyaert J., Ktistakis N. T., et al., "Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.", Science, vol. 350, issue 6257, pp. aac7365, 2015 Oct 09.
Geertsma, E. R., Chang Y-N., Shaik F. R., Neldner Y., Pardon E., Steyaert J., and Dutzler R., "Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.", Nat Struct Mol Biol, vol. 22, issue 10, pp. 803-8, 2015 Oct.
2014
Ehrnstorfer, I. A., Geertsma E. R., Pardon E., Steyaert J., and Dutzler R., "Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.", Nat Struct Mol Biol, vol. 21, issue 11, pp. 990-6, 2014 Nov.
Sterckx, Y. G. J., Haesaerts S., Van Melderen L., and Loris R., "Crystallization and preliminary X-ray analysis of two variants of the Escherichia coli O157 ParE2-PaaA2 toxin-antitoxin complex.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 9, pp. 1284-91, 2014 Sep.
Subedi, S., Moonens K., Romão E., Lo A., Vandenbussche G., Bugaytsova J., Muyldermans S., Borén T., and Remaut H., "Expression, purification and X-ray crystallographic analysis of the Helicobacter pylori blood group antigen-binding adhesin BabA.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 12, pp. 1631-5, 2014 Dec 01.

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