Publications

Found 199 results
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2018
Singh, R. Kumar, Feller A., Roovers M., Van Elder D., Wauters L., Droogmans L., and Versées W., "Structural and biochemical analysis of the dual-specificity Trm10 enzyme from prompts reconsideration of its catalytic mechanism.", RNA, vol. 24, issue 8, pp. 1080-1092, 2018 08.
Lee, S., Choi J., Mohanty J., Sousa L. P., Tome F., Pardon E., Steyaert J., Lemmon M. A., Lax I., and Schlessinger J., "Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.", Nature, vol. 553, issue 7689, pp. 501-505, 2018 01 25.
2017
Rosado, L. Astolfi, Wahni K., Degiacomi G., Pedre B., Young D., de la Rubia A. G., Boldrin F., Martens E., Marcos-Pascual L., Sancho-Vaello E., et al., "The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of .", J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 08 11.
Deyaert, E., Kortholt A., and Versées W., "The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 9, pp. 520-524, 2017 Sep 01.
Talavera, A., Tamman H., Ainelo A., Hadǽi S., Garcia-Pino A., Hõrak R., Konijnenberg A., and Loris R., "Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 8, pp. 455-462, 2017 Aug 01.
Hadži, S., Garcia-Pino A., Haesaerts S., Jurenas D., Gerdes K., Lah J., and Loris R., "Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.", Nucleic Acids Res, vol. 45, issue 8, pp. 4972-4983, 2017 May 05.
Gkekas, S., Singh R. Kumar, Shkumatov A. V., Messens J., Fauvart M., Verstraeten N., Michiels J., and Versées W., "Structural and biochemical analysis of ObgE, a central regulator of bacterial persistence.", J Biol Chem, vol. 292, issue 14, pp. 5871-5883, 2017 04 07.
Singh, R. Kumar, Steyaert J., and Versées W., "Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis.", Protein Sci, vol. 26, issue 5, pp. 985-996, 2017 05.
Miller, P. S., Scott S., Masiulis S., De Colibus L., Pardon E., Steyaert J., and A Aricescu R., "Structural basis for GABA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
Schubert, A. F., Gladkova C., Pardon E., Wagstaff J. L., Freund S. M. V., Steyaert J., Maslen S. L., and Komander D., "Structure of PINK1 in complex with its substrate ubiquitin.", Nature, vol. 552, issue 7683, pp. 51-56, 2017 12 07.
2016
Staus, D. P., Strachan R. T., Manglik A., Pani B., Kahsai A. W., Kim T. Hun, Wingler L. M., Ahn S., Chatterjee A., Masoudi A., et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
Jiang, X., Smirnova I., Kasho V., Wu J., Hirata K., Ke M., Pardon E., Steyaert J., Yan N., and H Kaback R., "Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.", Proc Natl Acad Sci U S A, vol. 113, issue 44, pp. 12420-12425, 2016 11 01.
Cho, K. Joon, Schepens B., Moonens K., Deng L., Fiers W., Remaut H., and Saelens X., "Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody.", J Virol, vol. 90, issue 1, pp. 611-5, 2016 01 01.
Egea-Jimenez, A. Luis, Gallardo R., Garcia-Pino A., Ivarsson Y., Wawrzyniak A. Maria, Kashyap R., Loris R., Schymkowitz J., Rousseau F., and Zimmermann P., "Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.", Nat Commun, vol. 7, pp. 12101, 2016 07 08.
Javaheri, A., Kruse T., Moonens K., Mejías-Luque R., Debraekeleer A., Asche C. I., Tegtmeyer N., Kalali B., Bach N. C., Sieber S. A., et al., "Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.", Nat Microbiol, vol. 2, pp. 16189, 2016 Oct 17.
Fischer, B., Lüthy K., Paesmans J., De Koninck C., Maes I., Swerts J., Kuenen S., Uytterhoeven V., Verstreken P., and Versées W., "Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.", Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
Van Laer, B., Roovers M., Wauters L., Kasprzak J. M., Dyzma M., Deyaert E., Singh R. Kumar, Feller A., Bujnicki J. M., Droogmans L., et al., "Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.", Nucleic Acids Res, vol. 44, issue 2, pp. 940-53, 2016 Jan 29.
Guaitoli, G., Raimondi F., Gilsbach B. K., Gómez-Llorente Y., Deyaert E., Renzi F., Li X., Schaffner A., Jagtap P. Kumar Anku, Boldt K., et al., "Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.", Proc Natl Acad Sci U S A, vol. 113, issue 30, pp. E4357-66, 2016 07 26.
Zorzini, V., Mernik A., Lah J., Sterckx Y. G. J., De Jonge N., Garcia-Pino A., De Greve H., Versées W., and Loris R., "Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.", J Biol Chem, vol. 291, issue 21, pp. 10950-60, 2016 May 20.
Sterckx, Y. G. - J., Jové T., Shkumatov A. V., Garcia-Pino A., Geerts L., De Kerpel M., Lah J., De Greve H., Van Melderen L., and Loris R., "A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.", J Mol Biol, vol. 428, issue 8, pp. 1589-603, 2016 Apr 24.
2015
Newman, J. A., Savitsky P., Allerston C. K., Bizard A. H., Özer Ö., Sarlós K., Liu Y., Pardon E., Steyaert J., Hickson I. D., et al., "Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.", Nucleic Acids Res, vol. 43, issue 10, pp. 5221-35, 2015 May 26.
Haesaerts, S., Buitrago J. Alexander, Loris R., Baeyens-Volant D., and Azarkan M., "Crystallization and preliminary X-ray analysis of four cysteine proteases from Ficus carica latex.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 4, pp. 459-65, 2015 Apr.
Hadži, S., Garcia-Pino A., Gerdes K., Lah J., and Loris R., "Crystallization of two operator complexes from the Vibrio cholerae HigBA2 toxin-antitoxin module.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 2, pp. 226-33, 2015 Feb.
Haynes, C. L. F., Ameloot P., Remaut H., Callewaert N., Sterckx Y. G. J., and Magez S., "Production, purification and crystallization of a trans-sialidase from Trypanosoma vivax.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 5, pp. 577-85, 2015 May.
Coppens, F., Iyyathurai J., Ruer S., Fioravanti A., Taganna J., Vereecke L., De Greve H., and Remaut H., "Structural and adhesive properties of the long polar fimbriae protein LpfD from adherent-invasive Escherichia coli.", Acta Crystallogr D Biol Crystallogr, vol. 71, issue Pt 8, pp. 1615-26, 2015 Aug.

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