Publications

Found 52 results
Filters: Keyword is Crystallography, X-Ray and Author is Wyns, Lode  [Clear All Filters]
2013
De Genst, E., P-H. Chan, E. Pardon, S-T. D. Hsu, J. R. Kumita, J. Christodoulou, L. Menzer, D. Y. Chirgadze, C. V. Robinson, S. Muyldermans, et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
2011
Domanska, K., S. Vanderhaegen, V. Srinivasan, E. Pardon, F. Dupeux, J. A. Marquez, S. Giorgetti, M. Stoppini, L. Wyns, V. Bellotti, et al., "Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic beta2-microglobulin variant.", Proc Natl Acad Sci U S A, vol. 108, issue 4, pp. 1314-9, 2011 Jan 25.
2010
De Genst, E., T. Guilliams, J. Wellens, E. M. O'Day, C. A. Waudby, S. Meehan, M. Dumoulin, S-T. D. Hsu, N. Cremades, K. H. G. Verschueren, et al., "Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.", J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
2009
Garcia-Pino, A., S. Martinez-Rodriguez, K. Wahni, L. Wyns, R. Loris, and J. Messens, "Coupling of domain swapping to kinetic stability in a thioredoxin mutant.", J Mol Biol, vol. 385, issue 5, pp. 1590-9, 2009 Feb 6.
Van Molle, I., K. Moonens, L. Buts, A. Garcia-Pino, S. Panjikar, L. Wyns, H. De Greve, and J. Bouckaert, "The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces.", Acta Crystallogr D Biol Crystallogr, vol. 65, issue Pt 5, pp. 411-20, 2009 May.
De Jonge, N., A. Garcia-Pino, L. Buts, S. Haesaerts, D. Charlier, K. Zangger, L. Wyns, H. De Greve, and R. Loris, "Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain.", Mol Cell, vol. 35, issue 2, pp. 154-63, 2009 Jul 31.
2008
Wellens, A., C. Garofalo, H. Nguyen, N. Van Gerven, R. Slättegård, J-P. Hernalsteens, L. Wyns, S. Oscarson, H. De Greve, S. Hultgren, et al., "Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex.", PLoS One, vol. 3, issue 4, pp. e2040, 2008.
Rodriguez, S. Martinez, S. Panjikar, K. Van Belle, L. Wyns, J. Messens, and R. Loris, "Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli.", Protein Sci, vol. 17, issue 4, pp. 681-90, 2008 Apr.
2007
Roos, G., A. Garcia-Pino, K. Van Belle, E. Brosens, K. Wahni, G. Vandenbussche, L. Wyns, R. Loris, and J. Messens, "The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin.", J Mol Biol, vol. 368, issue 3, pp. 800-11, 2007 May 4.
Garcia-Pino, A., L. Buts, L. Wyns, A. Imberty, and R. Loris, "How a plant lectin recognizes high mannose oligosaccharides.", Plant Physiol, vol. 144, issue 4, pp. 1733-41, 2007 Aug.
Messens, J., J-F. Collet, K. Van Belle, E. Brosens, R. Loris, and L. Wyns, "The oxidase DsbA folds a protein with a nonconsecutive disulfide.", J Biol Chem, vol. 282, issue 43, pp. 31302-7, 2007 Oct 26.
2006
Roos, G., E. Brosens, K. Wahni, A. Desmyter, S. Spinelli, L. Wyns, J. Messens, and R. Loris, "Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 62, issue Pt 12, pp. 1255-8, 2006 Dec 1.
Azarkan, M., A. Garcia-Pino, R. Dibiani, L. Wyns, R. Loris, and D. Baeyens-Volant, "Crystallization and preliminary X-ray analysis of a protease inhibitor from the latex of Carica papaya.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 62, issue Pt 12, pp. 1239-42, 2006 Dec 1.
Garcia-Pino, A., L. Buts, L. Wyns, and R. Loris, "Interplay between metal binding and cis/trans isomerization in legume lectins: structural and thermodynamic study of P. angolensis lectin.", J Mol Biol, vol. 361, issue 1, pp. 153-67, 2006 Aug 4.
De Genst, E., K. Silence, K. Decanniere, K. Conrath, R. Loris, J. Kinne, S. Muyldermans, and L. Wyns, "Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.", Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
Buts, L., A. Garcia-Pino, L. Wyns, and R. Loris, "Structural basis of carbohydrate recognition by a Man(alpha1-2)Man-specific lectin from Bowringia milbraedii.", Glycobiology, vol. 16, issue 7, pp. 635-40, 2006 Jul.
2005
Conrath, K., C. Vincke, B. Stijlemans, J. Schymkowitz, K. Decanniere, L. Wyns, S. Muyldermans, and R. Loris, "Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.", J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
Loris, R., A. Garcia-Pino, L. Buts, J. Bouckaert, S. Beeckmans, H. De Greve, and L. Wyns, "Crystallization and crystal manipulation of the Pterocarpus angolensis seed lectin.", Acta Crystallogr D Biol Crystallogr, vol. 61, issue Pt 6, pp. 685-9, 2005 Jun.
Garcia-Pino, A., R. Loris, L. Wyns, and L. Buts, "Crystallization and preliminary X-ray analysis of the Man(alpha1-2)Man-specific lectin from Bowringia mildbraedii in complex with its carbohydrate ligand.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 61, issue Pt 10, pp. 931-4, 2005 Oct 1.
Buts, L., N. De Jonge, R. Loris, L. Wyns, and M-H. Dao-Thi, "Crystallization of the C-terminal domain of the addiction antidote CcdA in complex with its toxin CcdB.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 61, issue Pt 10, pp. 949-52, 2005 Oct 1.
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
Buts, L., A. Wellens, I. Van Molle, L. Wyns, R. Loris, M. Lahmann, S. Oscarson, H. De Greve, and J. Bouckaert, "Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.", Acta Crystallogr D Biol Crystallogr, vol. 61, issue Pt 8, pp. 1149-59, 2005 Aug.
2004
De Genst, E., F. Handelberg, A. Van Meirhaeghe, S. Vynck, R. Loris, L. Wyns, and S. Muyldermans, "Chemical basis for the affinity maturation of a camel single domain antibody.", J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
Dao-Thi, M-H., L. Van Melderen, E. De Genst, L. Buts, A. Ranquin, L. Wyns, and R. Loris, "Crystallization of CcdB in complex with a GyrA fragment.", Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 6, pp. 1132-4, 2004 Jun.
Parret, A. H. A., L. Wyns, R. De Mot, and R. Loris, "Overexpression, purification and crystallization of bacteriocin LlpA from Pseudomonas sp. BW11M1.", Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 10, pp. 1922-4, 2004 Oct.

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