Publications

Found 16 results
Filters: Keyword is Crystallography, X-Ray and Author is Muyldermans, Serge  [Clear All Filters]
2014
Subedi, S., K. Moonens, E. Romão, A. Lo, G. Vandenbussche, J. Bugaytsova, S. Muyldermans, T. Borén, and H. Remaut, "Expression, purification and X-ray crystallographic analysis of the Helicobacter pylori blood group antigen-binding adhesin BabA.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 12, pp. 1631-5, 2014 Dec 01.
2013
De Genst, E., P-H. Chan, E. Pardon, S-T. D. Hsu, J. R. Kumita, J. Christodoulou, L. Menzer, D. Y. Chirgadze, C. V. Robinson, S. Muyldermans, et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
2009
Conrath, K., A. S. Pereira, C. E. Martins, C. G. Timóteo, P. Tavares, S. Spinelli, J. Kinne, C. Flaudrops, C. Cambillau, S. Muyldermans, et al., "Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase.", Protein Sci, vol. 18, issue 3, pp. 619-28, 2009 Mar.
Vincke, C., R. Loris, D. Saerens, S. Martinez-Rodriguez, S. Muyldermans, and K. Conrath, "General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.", J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
2006
De Genst, E., K. Silence, K. Decanniere, K. Conrath, R. Loris, J. Kinne, S. Muyldermans, and L. Wyns, "Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.", Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
2005
Conrath, K., C. Vincke, B. Stijlemans, J. Schymkowitz, K. Decanniere, L. Wyns, S. Muyldermans, and R. Loris, "Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.", J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
2004
De Genst, E., F. Handelberg, A. Van Meirhaeghe, S. Vynck, R. Loris, L. Wyns, and S. Muyldermans, "Chemical basis for the affinity maturation of a camel single domain antibody.", J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
2003
Loris, R., I. Marianovsky, J. Lah, T. Laeremans, H. Engelberg-Kulka, G. Glaser, S. Muyldermans, and L. Wyns, "Crystal structure of the intrinsically flexible addiction antidote MazE.", J Biol Chem, vol. 278, issue 30, pp. 28252-7, 2003 Jul 25.
2001
Decanniere, K., T. R. Transue, A. Desmyter, D. Maes, S. Muyldermans, and L. Wyns, "Degenerate interfaces in antigen-antibody complexes.", J Mol Biol, vol. 313, issue 3, pp. 473-8, 2001 Oct 26.
Muyldermans, S., "Single domain camel antibodies: current status.", J Biotechnol, vol. 74, issue 4, pp. 277-302, 2001 Jun.
2000
Decanniere, K., S. Muyldermans, and L. Wyns, "Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?", J Mol Biol, vol. 300, issue 1, pp. 83-91, 2000 Jun 30.
1999
Gupta, V., S. Muyldermans, L. Wyns, and D. M. Salunke, "The crystal structure of recombinant rat pancreatic RNase A.", Proteins, vol. 35, issue 1, pp. 1-12, 1999 Apr 1.
Decanniere, K., A. Desmyter, M. Lauwereys, M. A. Ghahroudi, S. Muyldermans, and L. Wyns, "A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.", Structure, vol. 7, issue 4, pp. 361-70, 1999 Apr 15.
1996
Desmyter, A., T. R. Transue, M. A. Ghahroudi, M. H. Thi, F. Poortmans, R. Hamers, S. Muyldermans, and L. Wyns, "Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme.", Nat Struct Biol, vol. 3, issue 9, pp. 803-11, 1996 Sep.
1994
Cerf, C., G. Lippens, V. Ramakrishnan, S. Muyldermans, A. Segers, L. Wyns, S. J. Wodak, and K. Hallenga, "Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: full assignment, tertiary structure, and comparison with the globular domain of histone H5.", Biochemistry, vol. 33, issue 37, pp. 11079-86, 1994 Sep 20.