Publications

Found 310 results

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2018

Bokor, M., Tantos Á., Meszaros A., Jenei B., Haminda R., Tompa P., and Tompa K., "Molecular Motions and Interactions in Aqueous Solutions of Thymosin-β , Stabilin C-Terminal Domain (CTD) and Their 1:1 Complex Studied by H NMR Spectroscopy.", Chemphyschem, vol. 19, issue 7, pp. 848-856, 2018 Apr 05.

Lee, S., Choi J., Mohanty J., Sousa L. P., Tome F., Pardon E., Steyaert J., Lemmon M. A., Lax I., and Schlessinger J., "Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.", Nature, vol. 553, issue 7689, pp. 501-505, 2018 01 25.

2017

Nguyen, H. Huy, Varadi M., Tompa P., and Pauwels K., "Affinity purification of human m-calpain through an intrinsically disordered inhibitor, calpastatin.", PLoS One, vol. 12, issue 3, pp. e0174125, 2017.

Ayoub, M. Akli, Crépieux P., Koglin M., Parmentier M., Pin J-P., Poupon A., Reiter E., Smit M., Steyaert J., Watier H., et al., "Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.", MAbs, vol. 9, issue 5, pp. 735-741, 2017 07.

Joncour, A., Desroy N., Housseman C., Bock X., Bienvenu N., Cherel L., Labeguere V., Peixoto C., Annoot D., Lepissier L., et al., "Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.", J Med Chem, vol. 60, issue 17, pp. 7371-7392, 2017 Sep 14.

Egea, J., Fabregat I., Frapart Y. M., Ghezzi P., Görlach A., Kietzmann T., Kubaichuk K., Knaus U. G., Lopez M. G., Olaso-Gonzalez G., et al., "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).", Redox Biol, vol. 13, pp. 94-162, 2017 10.

Moonens, K., and Remaut H., "Evolution and structural dynamics of bacterial glycan binding adhesins.", Curr Opin Struct Biol, vol. 44, pp. 48-58, 2017 06.

Schenck, S., Kunz L., Sahlender D., Pardon E., Geertsma E. R., Savtchouk I., Suzuki T., Neldner Y., Štefanić S., Steyaert J., et al., "Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.", Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 08 01.

Deyaert, E., Wauters L., Guaitoli G., Konijnenberg A., Leemans M., Terheyden S., Petrovic A., Gallardo R., Nederveen-Schippers L. M., Athanasopoulos P. S., et al., "A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover.", Nat Commun, vol. 8, issue 1, pp. 1008, 2017 10 18.

Raimondi, D., Orlando G., Messens J., and Vranken W. F., "Investigating the Molecular Mechanisms Behind Uncharacterized Cysteine Losses from Prediction of Their Oxidation State.", Hum Mutat, vol. 38, issue 1, pp. 86-94, 2017 01.

Barros-Álvarez, X., Kerchner K. M., Koh C. Yeow, Turley S., Pardon E., Steyaert J., Ranade R. M., J Gillespie R., Zhang Z., Verlinde C. L. M. J., et al., "Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.", Biochimie, vol. 138, pp. 124-136, 2017 Jul.

Manglik, A., Kobilka B. K., and Steyaert J., "Nanobodies to Study G Protein-Coupled Receptor Structure and Function.", Annu Rev Pharmacol Toxicol, vol. 57, pp. 19-37, 2017 01 06.

Boeynaems, S., Bogaert E., Kovacs D., Konijnenberg A., Timmerman E., Volkov A., Guharoy M., De Decker M., Jaspers T., Ryan V. H., et al., "Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.", Mol Cell, vol. 65, issue 6, pp. 1044-1055.e5, 2017 Mar 16.

Spaulding, C. N., Klein R. D., Ruer S., Kau A. L., Schreiber H. L., Cusumano Z. T., Dodson K. W., Pinkner J. S., Fremont D. H., Janetka J. W., et al., "Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.", Nature, vol. 546, issue 7659, pp. 528-532, 2017 06 22.

Abskharon, R., Dang J., Elfarash A., Wang Z., Shen P., Zou L. S., Hassan S., Wang F., Fujioka H., Steyaert J., et al., "Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors.", Microb Cell Fact, vol. 16, issue 1, pp. 170, 2017 Oct 04.

Miller, P. S., Scott S., Masiulis S., De Colibus L., Pardon E., Steyaert J., and A Aricescu R., "Structural basis for GABA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.

Willegems, K., and Efremov R. G., "Structural Details of the Ryanodine Receptor Calcium Release Channel and Its Gating Mechanism.", Adv Exp Med Biol, vol. 981, pp. 179-204, 2017.

Pauwels, K., Lebrun P., and Tompa P., "To be disordered or not to be disordered: is that still a question for proteins in the cell?", Cell Mol Life Sci, vol. 74, issue 17, pp. 3185-3204, 2017 09.

2016

Devree, B. T., Mahoney J. P., Vélez-Ruiz G. A., Rasmussen S. G. F., Kuszak A. J., Edwald E., Fung J-J., Manglik A., Masureel M., Du Y., et al., "Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.", Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.

Staus, D. P., Strachan R. T., Manglik A., Pani B., Kahsai A. W., Kim T. Hun, Wingler L. M., Ahn S., Chatterjee A., Masoudi A., et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.

Odongo, S., Sterckx Y. G. J., Stijlemans B., Pillay D., Baltz T., Muyldermans S., and Magez S., "An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase.", PLoS Negl Trop Dis, vol. 10, issue 2, pp. e0004420, 2016 Feb.

Messens, J., "Bioplastic hydroxyl radical trapping.", Nat Chem Biol, vol. 12, issue 5, pp. 307-8, 2016 May.

Pancsa, R., and Tompa P., "Coding Regions of Intrinsic Disorder Accommodate Parallel Functions.", Trends Biochem Sci, vol. 41, issue 11, pp. 898-906, 2016 Nov.

Vandervelde, A., Loris R., Danckaert J., and Gelens L., "Computational Methods to Model Persistence.", Methods Mol Biol, vol. 1333, pp. 207-40, 2016.

Hubin, E., Vanschoenwinkel B., Broersen K., De Deyn P. P., Koedam N., Van Nuland N. A., and Pauwels K., "Could ecosystem management provide a new framework for Alzheimer's disease?", Alzheimers Dement, vol. 12, issue 1, pp. 65-74.e1, 2016 Jan.

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