Publications

Found 324 results
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2018
Wauters, L., S. Terheyden, B. K. Gilsbach, M. Leemans, P. S. Athanasopoulos, G. Guaitoli, A. Wittinghofer, C. Johannes Gloeckner, W. Versées, and A. Kortholt, "Biochemical and kinetic properties of the complex Roco G-protein cycle.", Biol Chem, vol. 399, issue 12, pp. 1447-1456, 2018 11 27.
Bekesi, A., S. Abdellaoui, N. Holroyd, W. Van Delm, E. Pardon, J. Pauwels, K. Gevaert, J. Steyaert, S. Derveaux, A. Borysik, et al., "Challenges in the Structural-Functional Characterization of Multidomain, Partially Disordered Proteins CBP and p300: Preparing Native Proteins and Developing Nanobody Tools.", Methods Enzymol, vol. 611, pp. 607-675, 2018.
Pancsa, R., F. Zsolyomi, and P. Tompa, "Co-Evolution of Intrinsically Disordered Proteins with Folded Partners Witnessed by Evolutionary Couplings.", Int J Mol Sci, vol. 19, issue 11, 2018 Oct 25.
Nguyen, H. Huy, A. N. Volkov, G. Vandenbussche, P. Tompa, and K. Pauwels, "In vivo biotinylated calpastatin improves the affinity purification of human m-calpain.", Protein Expr Purif, vol. 145, pp. 77-84, 2018 05.
Henry, N., E-M. Krammer, F. Stengel, Q. Adams, F. Van Liefferinge, E. Hubin, R. Chaves, R. Efremov, R. Aebersold, G. Vandenbussche, et al., "Lipidated apolipoprotein E4 structure and its receptor binding mechanism determined by a combined cross-linking coupled to mass spectrometry and molecular dynamics approach.", PLoS Comput Biol, vol. 14, issue 6, pp. e1006165, 2018 06.
Bokor, M., Á. Tantos, A. Meszaros, B. Jenei, R. Haminda, P. Tompa, and K. Tompa, "Molecular Motions and Interactions in Aqueous Solutions of Thymosin-β , Stabilin C-Terminal Domain (CTD) and Their 1:1 Complex Studied by H NMR Spectroscopy.", Chemphyschem, vol. 19, issue 7, pp. 848-856, 2018 Apr 05.
Lee, S., J. Choi, J. Mohanty, L. P. Sousa, F. Tome, E. Pardon, J. Steyaert, M. A. Lemmon, I. Lax, and J. Schlessinger, "Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.", Nature, vol. 553, issue 7689, pp. 501-505, 2018 01 25.
2017
Nguyen, H. Huy, M. Varadi, P. Tompa, and K. Pauwels, "Affinity purification of human m-calpain through an intrinsically disordered inhibitor, calpastatin.", PLoS One, vol. 12, issue 3, pp. e0174125, 2017.
Ayoub, M. Akli, P. Crépieux, M. Koglin, M. Parmentier, J-P. Pin, A. Poupon, E. Reiter, M. Smit, J. Steyaert, H. Watier, et al., "Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.", MAbs, vol. 9, issue 5, pp. 735-741, 2017 07.
Joncour, A., N. Desroy, C. Housseman, X. Bock, N. Bienvenu, L. Cherel, V. Labeguere, C. Peixoto, D. Annoot, L. Lepissier, et al., "Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.", J Med Chem, vol. 60, issue 17, pp. 7371-7392, 2017 Sep 14.
Egea, J., I. Fabregat, Y. M. Frapart, P. Ghezzi, A. Görlach, T. Kietzmann, K. Kubaichuk, U. G. Knaus, M. G. Lopez, G. Olaso-Gonzalez, et al., "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).", Redox Biol, vol. 13, pp. 94-162, 2017 10.
Moonens, K., and H. Remaut, "Evolution and structural dynamics of bacterial glycan binding adhesins.", Curr Opin Struct Biol, vol. 44, pp. 48-58, 2017 06.
Schenck, S., L. Kunz, D. Sahlender, E. Pardon, E. R. Geertsma, I. Savtchouk, T. Suzuki, Y. Neldner, S. Štefanić, J. Steyaert, et al., "Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.", Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 08 01.
Deyaert, E., L. Wauters, G. Guaitoli, A. Konijnenberg, M. Leemans, S. Terheyden, A. Petrovic, R. Gallardo, L. M. Nederveen-Schippers, P. S. Athanasopoulos, et al., "A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover.", Nat Commun, vol. 8, issue 1, pp. 1008, 2017 10 18.
Raimondi, D., G. Orlando, J. Messens, and W. F. Vranken, "Investigating the Molecular Mechanisms Behind Uncharacterized Cysteine Losses from Prediction of Their Oxidation State.", Hum Mutat, vol. 38, issue 1, pp. 86-94, 2017 01.
Barros-Álvarez, X., K. M. Kerchner, C. Yeow Koh, S. Turley, E. Pardon, J. Steyaert, R. M. Ranade, R. J Gillespie, Z. Zhang, C. L. M. J. Verlinde, et al., "Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.", Biochimie, vol. 138, pp. 124-136, 2017 Jul.
Contreras-Martos, S., A. Piai, S. Kosol, M. Varadi, A. Bekesi, P. Lebrun, A. N. Volkov, K. Gevaert, R. Pierattelli, I. C. Felli, et al., "Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.", Sci Rep, vol. 7, issue 1, pp. 4676, 2017 07 05.
Manglik, A., B. K. Kobilka, and J. Steyaert, "Nanobodies to Study G Protein-Coupled Receptor Structure and Function.", Annu Rev Pharmacol Toxicol, vol. 57, pp. 19-37, 2017 01 06.
Boeynaems, S., E. Bogaert, D. Kovacs, A. Konijnenberg, E. Timmerman, A. Volkov, M. Guharoy, M. De Decker, T. Jaspers, V. H. Ryan, et al., "Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.", Mol Cell, vol. 65, issue 6, pp. 1044-1055.e5, 2017 Mar 16.
Spaulding, C. N., R. D. Klein, S. Ruer, A. L. Kau, H. L. Schreiber, Z. T. Cusumano, K. W. Dodson, J. S. Pinkner, D. H. Fremont, J. W. Janetka, et al., "Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.", Nature, vol. 546, issue 7659, pp. 528-532, 2017 06 22.
Abskharon, R., J. Dang, A. Elfarash, Z. Wang, P. Shen, L. S. Zou, S. Hassan, F. Wang, H. Fujioka, J. Steyaert, et al., "Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors.", Microb Cell Fact, vol. 16, issue 1, pp. 170, 2017 Oct 04.
Miller, P. S., S. Scott, S. Masiulis, L. De Colibus, E. Pardon, J. Steyaert, and R. A Aricescu, "Structural basis for GABA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
Willegems, K., and R. G. Efremov, "Structural Details of the Ryanodine Receptor Calcium Release Channel and Its Gating Mechanism.", Adv Exp Med Biol, vol. 981, pp. 179-204, 2017.

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