Publications

Found 9 results

Filters: Keyword is Structure-Activity Relationship and Author is Jan Steyaert [Clear All Filters]

2017

Joncour, A., N. Desroy, C. Housseman, X. Bock, N. Bienvenu, L. Cherel, V. Labeguere, C. Peixoto, D. Annoot, L. Lepissier, et al., "Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.", J Med Chem, vol. 60, issue 17, pp. 7371-7392, 2017 Sep 14.

Wohlkonig, A., H. Remaut, M. Moune, A. Tanina, F. Meyer, M. Desroses, J. Steyaert, N. Willand, A. R. Baulard, and R. Wintjens, "Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.", Biochem Biophys Res Commun, vol. 487, issue 2, pp. 403-408, 2017 05 27.

2015

Sounier, R., C. Mas, J. Steyaert, T. Laeremans, A. Manglik, W. Huang, B. K. Kobilka, H. Déméné, and S. Granier, "Propagation of conformational changes during μ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 375-8, 2015 Aug 20.

Huang, W., A. Manglik, A. J. Venkatakrishnan, T. Laeremans, E. N. Feinberg, A. L. Sanborn, H. E. Kato, K. E. Livingston, T. S. Thorsen, R. C. Kling, et al., "Structural insights into µ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.

2003

Loverix, S., and J. Steyaert, "Ribonucleases: from prototypes to therapeutic targets?", Curr Med Chem, vol. 10, issue 9, pp. 779-85, 2003 May.

2001

Versées, W., K. Decanniere, R. Pellé, J. Depoorter, E. Brosens, D. W. Parkin, and J. Steyaert, "Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.", J Mol Biol, vol. 307, issue 5, pp. 1363-79, 2001 Apr 13.

1999

Langhorst, U., R. Loris, V. P. Denisov, J. Doumen, P. Roose, D. Maes, B. Halle, and J. Steyaert, "Dissection of the structural and functional role of a conserved hydration site in RNase T1.", Protein Sci, vol. 8, issue 4, pp. 722-30, 1999 Apr.

1997

Loverix, S., J. Doumen, and J. Steyaert, "Additivity of protein-guanine interactions in ribonuclease T1.", J Biol Chem, vol. 272, issue 15, pp. 9635-9, 1997 Apr 11.

1996

Doumen, J., M. Gonciarz, I. Zegers, R. Loris, L. Wyns, and J. Steyaert, "A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.", Protein Sci, vol. 5, issue 8, pp. 1523-30, 1996 Aug.