Publications
Found 22 results
Filters: Keyword is Antibodies, Protozoan [Clear All Filters]
"An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase.",
PLoS Negl Trop Dis, vol. 10, issue 2, pp. e0004420, 2016 Feb.
"Detection of pathogen-specific antibodies by loop-mediated isothermal amplification.",
Clin Vaccine Immunol, vol. 22, issue 4, pp. 374-80, 2015 Apr.
"Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis.",
PLoS Pathog, vol. 11, issue 6, pp. e1004942, 2015 Jun.
"Chronic Trypanosoma congolense infections in mice cause a sustained disruption of the B-cell homeostasis in the bone marrow and spleen.",
Parasite Immunol, vol. 36, issue 5, pp. 187-98, 2014 May.
"Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein.",
Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 3, pp. 270-4, 2013 Mar 1.
"Affinity is an important determinant of the anti-trypanosome activity of nanobodies.",
PLoS Negl Trop Dis, vol. 6, issue 11, pp. e1902, 2012.
"Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier.",
Br J Pharmacol, vol. 165, issue 7, pp. 2341-53, 2012 Apr.
"High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.",
PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
"T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis.",
PLoS Pathog, vol. 7, issue 6, pp. e1002089, 2011 Jun.
"African trypanosomiasis and antibodies: implications for vaccination, therapy and diagnosis.",
Future Microbiol, vol. 4, issue 8, pp. 1075-87, 2009 Oct.
"Contributions of experimental mouse models to the understanding of African trypanosomiasis.",
Trends Parasitol, vol. 24, issue 9, pp. 411-8, 2008 Sep.
"Interleukin-12p70 deficiency increases survival and diminishes pathology in Trypanosoma congolense infection.",
J Infect Dis, vol. 198, issue 9, pp. 1284-91, 2008 Nov 1.
"Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens.",
J Immunol Methods, vol. 329, issue 1-2, pp. 138-50, 2008 Jan 1.
"The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice.",
PLoS Pathog, vol. 4, issue 8, pp. e1000122, 2008.
"Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses.",
PLoS Pathog, vol. 4, issue 5, pp. e1000078, 2008 May.
"African trypanosomosis: from immune escape and immunopathology to immune intervention.",
Vet Parasitol, vol. 148, issue 1, pp. 3-13, 2007 Aug 19.
"Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes.",
Exp Parasitol, vol. 115, issue 2, pp. 173-80, 2007 Feb.
"Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.",
Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
"Interferon-gamma and nitric oxide in combination with antibodies are key protective host immune factors during trypanosoma congolense Tc13 Infections.",
J Infect Dis, vol. 193, issue 11, pp. 1575-83, 2006 Jun 1.
"Control of experimental Trypanosoma brucei infections occurs independently of lymphotoxin-alpha induction.",
Infect Immun, vol. 70, issue 3, pp. 1342-51, 2002 Mar.
"Antibodies raised against the flagellar pocket fraction of Trypanosoma brucei preferentially recognize HSP60 in cDNA expression library.",
Parasite Immunol, vol. 22, issue 12, pp. 639-50, 2000 Dec.
"Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei.",
Infect Immun, vol. 68, issue 2, pp. 848-60, 2000 Feb.