Publications

Found 45 results
Filters: Keyword is Camelids, New World  [Clear All Filters]
2017
Schenck, S., L. Kunz, D. Sahlender, E. Pardon, E. R. Geertsma, I. Savtchouk, T. Suzuki, Y. Neldner, S. Štefanić, J. Steyaert, et al., "Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.", Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 08 01.
2016
Peyrassol, X., T. Laeremans, M. Gouwy, V. Lahura, M. Debulpaep, J. Van Damme, J. Steyaert, M. Parmentier, and I. Langer, "Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor.", J Immunol, vol. 196, issue 6, pp. 2893-901, 2016 Mar 15.
Claes, K., K. Vandewalle, B. Laukens, T. Laeremans, O. Vosters, I. Langer, M. Parmentier, J. Steyaert, and N. Callewaert, "Modular Integrated Secretory System Engineering in Pichia pastoris To Enhance G-Protein Coupled Receptor Expression.", ACS Synth Biol, vol. 5, issue 10, pp. 1070-1075, 2016 10 21.
2015
Moonens, K., I. Van den Broeck, E. Okello, E. Pardon, M. De Kerpel, H. Remaut, and H. De Greve, "Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.", Vet Res, vol. 46, pp. 14, 2015 Feb 24.
2014
Obishakin, E., B. Stijlemans, J. Santi-Rocca, I. Vandenberghe, B. Devreese, S. Muldermans, P. Bastin, and S. Magez, "Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes.", PLoS One, vol. 9, issue 12, pp. e115893, 2014.
Nunes-Silva, S., S. Gangnard, M. Vidal, A. Vuchelen, S. Dechavanne, S. Chan, E. Pardon, J. Steyaert, S. Ramboarina, A. Chêne, et al., "Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain.", Sci Rep, vol. 4, pp. 7373, 2014 Dec 09.
Lo, A. W. H., K. Moonens, M. De Kerpel, L. Brys, E. Pardon, H. Remaut, and H. De Greve, "The molecular mechanism of Shiga toxin Stx2e neutralization by a single-domain antibody targeting the cell receptor-binding domain.", J Biol Chem, vol. 289, issue 36, pp. 25374-81, 2014 Sep 05.
Moonens, K., M. De Kerpel, A. Coddens, E. Cox, E. Pardon, H. Remaut, and H. De Greve, "Nanobody mediated inhibition of attachment of F18 Fimbriae expressing Escherichia coli.", PLoS One, vol. 9, issue 12, pp. e114691, 2014.
Ditlev, S. B., R. Florea, M. A. Nielsen, T. G. Theander, S. Magez, P. Boeuf, and A. Salanti, "Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.", PLoS One, vol. 9, issue 1, pp. e84981, 2014.
2013
Sohier, J. S., C. Laurent, A. Chevigné, E. Pardon, V. Srinivasan, U. Wernery, P. Lassaux, J. Steyaert, and M. Galleni, "Allosteric inhibition of VIM metallo-β-lactamases by a camelid nanobody.", Biochem J, vol. 450, issue 3, pp. 477-86, 2013 Mar 15.
Paraschiv, G., C. Vincke, P. Czaplewska, M. Manea, S. Muyldermans, and M. Przybylski, "Epitope structure and binding affinity of single chain llama anti-β-amyloid antibodies revealed by proteolytic excision affinity-mass spectrometry.", J Mol Recognit, vol. 26, issue 1, pp. 1-9, 2013 Jan.
Oyen, D., R. Wechselberger, V. Srinivasan, J. Steyaert, and J. N. Barlow, "Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihydrofolate reductase of Escherichia coli.", Biochim Biophys Acta, vol. 1834, issue 10, pp. 2147-57, 2013 Oct.
Muyldermans, S., "Nanobodies: natural single-domain antibodies.", Annu Rev Biochem, vol. 82, pp. 775-97, 2013.
Löw, C., Y. Hoe Yau, E. Pardon, C. Jegerschöld, L. Wåhlin, E. M. Quistgaard, P. Moberg, S. Geifman-Shochat, J. Steyaert, and P. Nordlund, "Nanobody mediated crystallization of an archeal mechanosensitive channel.", PLoS One, vol. 8, issue 10, pp. e77984, 2013.
Nguyen-Duc, T., E. Peeters, S. Muyldermans, D. Charlier, and G. Hassanzadeh-Ghassabeh, "Nanobody(R)-based chromatin immunoprecipitation/micro-array analysis for genome-wide identification of transcription factor DNA binding sites.", Nucleic Acids Res, vol. 41, issue 5, pp. e59, 2013 Mar 1.
Unciti-Broceta, J. Diego, T. Del Castillo, M. Soriano, S. Magez, and J. A. Garcia-Salcedo, "Novel therapy based on camelid nanobodies.", Ther Deliv, vol. 4, issue 10, pp. 1321-36, 2013 Oct.
Vuchelen, A., E. Pardon, J. Steyaert, B. Gamain, R. Loris, N. A. J. van Nuland, and S. Ramboarina, "Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 3, pp. 270-4, 2013 Mar 1.
2012
Behdani, M., S. Zeinali, H. Khanahmad, M. Karimipour, N. Asadzadeh, K. Azadmanesh, A. Khabiri, S. Schoonooghe, M. Habibi Anbouhi, G. Hassanzadeh-Ghassabeh, et al., "Generation and characterization of a functional Nanobody against the vascular endothelial growth factor receptor-2; angiogenesis cell receptor.", Mol Immunol, vol. 50, issue 1-2, pp. 35-41, 2012 Feb.
Vincke, C., C. Gutiérrez, U. Wernery, N. Devoogdt, G. Hassanzadeh-Ghassabeh, and S. Muyldermans, "Generation of single domain antibody fragments derived from camelids and generation of manifold constructs.", Methods Mol Biol, vol. 907, pp. 145-76, 2012.
Vincke, C., and S. Muyldermans, "Introduction to heavy chain antibodies and derived Nanobodies.", Methods Mol Biol, vol. 911, pp. 15-26, 2012.
2011
Domanska, K., S. Vanderhaegen, V. Srinivasan, E. Pardon, F. Dupeux, J. A. Marquez, S. Giorgetti, M. Stoppini, L. Wyns, V. Bellotti, et al., "Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic beta2-microglobulin variant.", Proc Natl Acad Sci U S A, vol. 108, issue 4, pp. 1314-9, 2011 Jan 25.
Oyen, D., V. Srinivasan, J. Steyaert, and J. N. Barlow, "Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition.", J Mol Biol, vol. 407, issue 1, pp. 138-48, 2011 Mar 18.
Bouhaouala-Zahar, B., R. Ben Abderrazek, I. Hmila, N. Abidi, S. Muyldermans, and M. El Ayeb, "Immunological aspects of scorpion toxins: current status and perspectives.", Inflamm Allergy Drug Targets, vol. 10, issue 5, pp. 358-68, 2011 Oct.
Vaneycken, I., N. Devoogdt, N. Van Gassen, C. Vincke, C. Xavier, U. Wernery, S. Muyldermans, T. Lahoutte, and V. Caveliers, "Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer.", FASEB J, vol. 25, issue 7, pp. 2433-46, 2011 Jul.
Rasmussen, S. G. F., H-J. Choi, J. Jose Fung, E. Pardon, P. Casarosa, P. Seok Chae, B. T. Devree, D. M. Rosenbaum, F. Sun Thian, T. Sun Kobilka, et al., "Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.", Nature, vol. 469, issue 7329, pp. 175-80, 2011 Jan 13.

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