Publications
Found 21 results
Filters: Keyword is Anti-Bacterial Agents [Clear All Filters]
"The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of .",
J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 08 11.
"Computational Methods to Model Persistence.",
Methods Mol Biol, vol. 1333, pp. 207-40, 2016.
"Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.",
Mol Cell, vol. 59, issue 1, pp. 9-21, 2015 Jul 02.
"Virulence-targeted Antibacterials: Concept, Promise, and Susceptibility to Resistance Mechanisms.",
Chem Biol Drug Des, vol. 86, issue 4, pp. 379-99, 2015 Oct.
"Bacterial surface appendages as targets for novel antibacterial therapeutics.",
Future Microbiol, vol. 9, issue 7, pp. 887-900, 2014.
"A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.",
Pathog Dis, vol. 71, issue 1, pp. 39-54, 2014 Jun.
"Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization.",
J Antimicrob Chemother, vol. 69, issue 4, pp. 1017-26, 2014 Apr.
"Chemical attenuation of pilus function and assembly in Gram-negative bacteria.",
Curr Opin Microbiol, vol. 16, issue 1, pp. 85-92, 2013 Feb.
"Structural determinants for activity and specificity of the bacterial toxin LlpA.",
PLoS Pathog, vol. 9, issue 2, pp. e1003199, 2013 Feb.
"MMBL proteins: from lectin to bacteriocin.",
Biochem Soc Trans, vol. 40, issue 6, pp. 1553-9, 2012 Dec 1.
"Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease.",
Chem Biol, vol. 18, issue 9, pp. 1167-78, 2011 Sep 23.
"Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition.",
Drugs, vol. 70, issue 6, pp. 651-79, 2010 Apr 16.
"Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity.",
J Med Chem, vol. 53, issue 15, pp. 5690-5, 2010 Aug 12.
"Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70.",
Biochem J, vol. 432, issue 3, pp. 495-504, 2010 Dec 15.
"Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.",
Bioorg Med Chem Lett, vol. 19, issue 13, pp. 3593-7, 2009 Jul 1.
"Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex.",
PLoS One, vol. 3, issue 4, pp. e2040, 2008.
"Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria.",
Proc Natl Acad Sci U S A, vol. 103, issue 47, pp. 17897-902, 2006 Nov 21.
"Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis.",
FEBS Lett, vol. 579, issue 9, pp. 1917-22, 2005 Mar 28.
"The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics.",
Nat Struct Mol Biol, vol. 11, issue 10, pp. 963-7, 2004 Oct.
"NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles. Conformational changes are a key to antimicrobial activity.",
J Biol Chem, vol. 278, issue 15, pp. 13110-7, 2003 Apr 11.
"Mapping the targeted membrane pore formation mechanism by solution NMR: the nisin Z and lipid II interaction in SDS micelles.",
Biochemistry, vol. 41, issue 24, pp. 7670-6, 2002 Jun 18.