Publications

Found 16 results
Filters: Keyword is Camels and Author is Dirk Saerens  [Clear All Filters]
2012
Govaert, J., M. Pellis, N. Deschacht, C. Vincke, K. Conrath, S. Muyldermans, and D. Saerens, "Dual beneficial effect of interloop disulfide bond for single domain antibody fragments.", J Biol Chem, vol. 287, issue 3, pp. 1970-9, 2012 Jan 13.
2011
Ben Abderrazek, R., C. Vincke, I. Hmila, D. Saerens, N. Abidi, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin.", Protein Eng Des Sel, vol. 24, issue 9, pp. 727-35, 2011 Sep.
2010
Hmila, I., D. Saerens, R. Ben Abderrazek, C. Vincke, N. Abidi, Z. Benlasfar, J. Govaert, M. El Ayeb, B. Bouhaouala-Zahar, and S. Muyldermans, "A bispecific nanobody to provide full protection against lethal scorpion envenoming.", FASEB J, vol. 24, issue 9, pp. 3479-89, 2010 Sep.
2009
Muyldermans, S., T. Nath Baral, C. V Retamozzo, P. De Baetselier, E. De Genst, J. Kinne, H. Leonhardt, S. Magez, V. K. Nguyen, H. Revets, et al., "Camelid immunoglobulins and nanobody technology.", Vet Immunol Immunopathol, vol. 128, issue 1-3, pp. 178-83, 2009 Mar 15.
Vincke, C., R. Loris, D. Saerens, S. Martinez-Rodriguez, S. Muyldermans, and K. Conrath, "General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.", J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
Ben Abderrazek, R., I. Hmila, C. Vincke, Z. Benlasfar, M. Pellis, H. Dabbek, D. Saerens, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "Identification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom.", Biochem J, vol. 424, issue 2, pp. 263-72, 2009 Dec 1.
Deckers, N., D. Saerens, K. Kanobana, K. Conrath, B. Victor, U. Wernery, J. Vercruysse, S. Muyldermans, and P. Dorny, "Nanobodies, a promising tool for species-specific diagnosis of Taenia solium cysticercosis.", Int J Parasitol, vol. 39, issue 5, pp. 625-33, 2009 Apr.
2008
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
Saerens, D., B. Stijlemans, T. Nath Baral, G. Thanh Nguy Thi, U. Wernery, S. Magez, P. De Baetselier, S. Muyldermans, and K. Conrath, "Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens.", J Immunol Methods, vol. 329, issue 1-2, pp. 138-50, 2008 Jan 1.
Hmila, I., B. Abderrazek R, D. Saerens, Z. Benlasfar, K. Conrath, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "VHH, bivalent domains and chimeric Heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI'.", Mol Immunol, vol. 45, issue 14, pp. 3847-56, 2008 Aug.
2006
De Genst, E., D. Saerens, S. Muyldermans, and K. Conrath, "Antibody repertoire development in camelids.", Dev Comp Immunol, vol. 30, issue 1-2, pp. 187-98, 2006.
2005
Saerens, D., F. Frederix, G. Reekmans, K. Conrath, K. Jans, L. Brys, L. Huang, E. Bosmans, G. Maes, G. Borghs, et al., "Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing.", Anal Chem, vol. 77, issue 23, pp. 7547-55, 2005 Dec 1.
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
Huang, L., G. Reekmans, D. Saerens, J-M. Friedt, F. Frederix, L. Francis, S. Muyldermans, A. Campitelli, and C. Van Hoof, "Prostate-specific antigen immunosensing based on mixed self-assembled monolayers, camel antibodies and colloidal gold enhanced sandwich assays.", Biosens Bioelectron, vol. 21, issue 3, pp. 483-90, 2005 Sep 15.
2004
Saerens, D., J. Kinne, E. Bosmans, U. Wernery, S. Muyldermans, and K. Conrath, "Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.", J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.
Pleschberger, M., D. Saerens, S. Weigert, U. B. Sleytr, S. Muyldermans, M. Sára, and E. M. Egelseer, "An S-layer heavy chain camel antibody fusion protein for generation of a nanopatterned sensing layer to detect the prostate-specific antigen by surface plasmon resonance technology.", Bioconjug Chem, vol. 15, issue 3, pp. 664-71, 2004 May-Jun.