Publications

Found 21 results
Filters: Keyword is Antibody Affinity  [Clear All Filters]
2013
Vercruysse, T., E. Boons, T. Venken, E. Vanstreels, A. Voet, J. Steyaert, M. De Maeyer, and D. Daelemans, "Mapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein Rev.", PLoS One, vol. 8, issue 4, pp. e60259, 2013.
Muyldermans, S., "Nanobodies: natural single-domain antibodies.", Annu Rev Biochem, vol. 82, pp. 775-97, 2013.
Fleetwood, F., N. Devoogdt, M. Pellis, U. Wernery, S. Muyldermans, S. Ståhl, and J. Löfblom, "Surface display of a single-domain antibody library on Gram-positive bacteria.", Cell Mol Life Sci, vol. 70, issue 6, pp. 1081-93, 2013 Mar.
2012
Caljon, G., B. Stijlemans, D. Saerens, J. Van Den Abbeele, S. Muyldermans, S. Magez, and P. De Baetselier, "Affinity is an important determinant of the anti-trypanosome activity of nanobodies.", PLoS Negl Trop Dis, vol. 6, issue 11, pp. e1902, 2012.
Pellis, M., E. Pardon, K. Zolghadr, U. Rothbauer, C. Vincke, J. Kinne, I. Dierynck, K. Hertogs, H. Leonhardt, J. Messens, et al., "A bacterial-two-hybrid selection system for one-step isolation of intracellularly functional Nanobodies.", Arch Biochem Biophys, vol. 526, issue 2, pp. 114-23, 2012 Oct 15.
2011
Domanska, K., S. Vanderhaegen, V. Srinivasan, E. Pardon, F. Dupeux, J. A. Marquez, S. Giorgetti, M. Stoppini, L. Wyns, V. Bellotti, et al., "Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic beta2-microglobulin variant.", Proc Natl Acad Sci U S A, vol. 108, issue 4, pp. 1314-9, 2011 Jan 25.
Roovers, R. C., M. J. W. D. Vosjan, T. Laeremans, R. el Khoulati, R. C. G. de Bruin, K. M. Ferguson, A. J. Verkleij, G. A. M. S. van Dongen, and P. M. P. van Be Henegouwen, "A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth.", Int J Cancer, vol. 129, issue 8, pp. 2013-24, 2011 Oct 15.
Ben Abderrazek, R., C. Vincke, I. Hmila, D. Saerens, N. Abidi, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin.", Protein Eng Des Sel, vol. 24, issue 9, pp. 727-35, 2011 Sep.
Stijlemans, B., G. Caljon, S. Kumar A. Natesan, D. Saerens, K. Conrath, D. Pérez-Morga, J. N. Skepper, A. Nikolaou, L. Brys, E. Pays, et al., "High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.", PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
2010
De Genst, E., T. Guilliams, J. Wellens, E. M. O'Day, C. A. Waudby, S. Meehan, M. Dumoulin, S-T. D. Hsu, N. Cremades, K. H. G. Verschueren, et al., "Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.", J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
2009
Conrath, K., A. S. Pereira, C. E. Martins, C. G. Timóteo, P. Tavares, S. Spinelli, J. Kinne, C. Flaudrops, C. Cambillau, S. Muyldermans, et al., "Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase.", Protein Sci, vol. 18, issue 3, pp. 619-28, 2009 Mar.
Deckers, N., D. Saerens, K. Kanobana, K. Conrath, B. Victor, U. Wernery, J. Vercruysse, S. Muyldermans, and P. Dorny, "Nanobodies, a promising tool for species-specific diagnosis of Taenia solium cysticercosis.", Int J Parasitol, vol. 39, issue 5, pp. 625-33, 2009 Apr.
2008
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
2006
De Genst, E., K. Silence, K. Decanniere, K. Conrath, R. Loris, J. Kinne, S. Muyldermans, and L. Wyns, "Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.", Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
2004
De Genst, E., F. Handelberg, A. Van Meirhaeghe, S. Vynck, R. Loris, L. Wyns, and S. Muyldermans, "Chemical basis for the affinity maturation of a camel single domain antibody.", J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
2002
Cortez-Retamozo, V., M. Lauwereys, G. Hassanzade Gh, M. Gobert, K. Conrath, S. Muyldermans, P. De Baetselier, and H. Revets, "Efficient tumor targeting by single-domain antibody fragments of camels.", Int J Cancer, vol. 98, issue 3, pp. 456-62, 2002 Mar 20.
2001
Desmyter, A., K. Decanniere, S. Muyldermans, and L. Wyns, "Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody.", J Biol Chem, vol. 276, issue 28, pp. 26285-90, 2001 Jul 13.
Nguyen, V. K., A. Desmyter, and S. Muyldermans, "Functional heavy-chain antibodies in Camelidae.", Adv Immunol, vol. 79, pp. 261-96, 2001.
1999
Decanniere, K., A. Desmyter, M. Lauwereys, M. A. Ghahroudi, S. Muyldermans, and L. Wyns, "A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.", Structure, vol. 7, issue 4, pp. 361-70, 1999 Apr 15.
1998
Lauwereys, M., A. M Ghahroudi, A. Desmyter, J. Kinne, W. Hölzer, E. De Genst, L. Wyns, and S. Muyldermans, "Potent enzyme inhibitors derived from dromedary heavy-chain antibodies.", EMBO J, vol. 17, issue 13, pp. 3512-20, 1998 Jul 1.
1997
M Ghahroudi, A., A. Desmyter, L. Wyns, R. Hamers, and S. Muyldermans, "Selection and identification of single domain antibody fragments from camel heavy-chain antibodies.", FEBS Lett, vol. 414, issue 3, pp. 521-6, 1997 Sep 15.