Publications
Found 45 results
Filters: Keyword is Immunoglobulin Heavy Chains [Clear All Filters]
"Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes.",
PLoS One, vol. 9, issue 12, pp. e115893, 2014.
"Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.",
PLoS One, vol. 9, issue 1, pp. e84981, 2014.
"Nanobodies: natural single-domain antibodies.",
Annu Rev Biochem, vol. 82, pp. 775-97, 2013.
"Resolution of an immunodiagnostic dilemma: heavy chain chimeric antibodies for species in which plasmocytomas are unknown.",
Mol Immunol, vol. 53, issue 1-2, pp. 140-8, 2013 Jan.
"Dual beneficial effect of interloop disulfide bond for single domain antibody fragments.",
J Biol Chem, vol. 287, issue 3, pp. 1970-9, 2012 Jan 13.
"Generation of single domain antibody fragments derived from camelids and generation of manifold constructs.",
Methods Mol Biol, vol. 907, pp. 145-76, 2012.
"Introduction to heavy chain antibodies and derived Nanobodies.",
Methods Mol Biol, vol. 911, pp. 15-26, 2012.
"A case of convergence: why did a simple alternative to canonical antibodies arise in sharks and camels?",
PLoS Biol, vol. 9, issue 8, pp. e1001120, 2011 Aug.
"Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin.",
Protein Eng Des Sel, vol. 24, issue 9, pp. 727-35, 2011 Sep.
"Isolation of antigen-binding camelid heavy chain antibody fragments (nanobodies) from an immune library displayed on the surface of Pichia pastoris.",
J Biotechnol, vol. 145, issue 2, pp. 93-8, 2010 Jan 15.
"A novel promiscuous class of camelid single-domain antibody contributes to the antigen-binding repertoire.",
J Immunol, vol. 184, issue 10, pp. 5696-704, 2010 May 15.
"Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase.",
Protein Sci, vol. 18, issue 3, pp. 619-28, 2009 Mar.
"Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.",
Structure, vol. 17, issue 2, pp. 255-65, 2009 Feb 13.
"Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.",
J Struct Biol, vol. 166, issue 1, pp. 8-15, 2009 Apr.
"Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.",
J Mol Biol, vol. 377, issue 2, pp. 478-88, 2008 Mar 21.
"Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR Nanobodies.",
Cancer Immunol Immunother, vol. 56, issue 3, pp. 303-317, 2007 Mar.
"Antibody repertoire development in camelids.",
Dev Comp Immunol, vol. 30, issue 1-2, pp. 187-98, 2006.
"Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.",
Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
"Heavy-chain-only antibody expression and B-cell development in the mouse.",
Crit Rev Immunol, vol. 26, issue 5, pp. 377-90, 2006.
"Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.",
Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
"Targeting and tracing antigens in live cells with fluorescent nanobodies.",
Nat Methods, vol. 3, issue 11, pp. 887-9, 2006 Nov.
"Expression of a dromedary heavy chain-only antibody and B cell development in the mouse.",
J Immunol, vol. 175, issue 6, pp. 3769-79, 2005 Sep 15.
"Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.",
J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
"Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.",
J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
"Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.",
J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.