Publications
Found 39 results
Filters: Keyword is Immunoglobulin Heavy Chains and Author is S Muyldermans [Clear All Filters]
"Nanobodies: natural single-domain antibodies.",
Annu Rev Biochem, vol. 82, pp. 775-97, 2013.
"Resolution of an immunodiagnostic dilemma: heavy chain chimeric antibodies for species in which plasmocytomas are unknown.",
Mol Immunol, vol. 53, issue 1-2, pp. 140-8, 2013 Jan.
"Dual beneficial effect of interloop disulfide bond for single domain antibody fragments.",
J Biol Chem, vol. 287, issue 3, pp. 1970-9, 2012 Jan 13.
"Generation of single domain antibody fragments derived from camelids and generation of manifold constructs.",
Methods Mol Biol, vol. 907, pp. 145-76, 2012.
"Introduction to heavy chain antibodies and derived Nanobodies.",
Methods Mol Biol, vol. 911, pp. 15-26, 2012.
"A case of convergence: why did a simple alternative to canonical antibodies arise in sharks and camels?",
PLoS Biol, vol. 9, issue 8, pp. e1001120, 2011 Aug.
"Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin.",
Protein Eng Des Sel, vol. 24, issue 9, pp. 727-35, 2011 Sep.
"A novel promiscuous class of camelid single-domain antibody contributes to the antigen-binding repertoire.",
J Immunol, vol. 184, issue 10, pp. 5696-704, 2010 May 15.
"Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase.",
Protein Sci, vol. 18, issue 3, pp. 619-28, 2009 Mar.
"Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.",
J Mol Biol, vol. 377, issue 2, pp. 478-88, 2008 Mar 21.
"Antibody repertoire development in camelids.",
Dev Comp Immunol, vol. 30, issue 1-2, pp. 187-98, 2006.
"Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.",
Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
"Heavy-chain-only antibody expression and B-cell development in the mouse.",
Crit Rev Immunol, vol. 26, issue 5, pp. 377-90, 2006.
"Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.",
Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
"Targeting and tracing antigens in live cells with fluorescent nanobodies.",
Nat Methods, vol. 3, issue 11, pp. 887-9, 2006 Nov.
"Expression of a dromedary heavy chain-only antibody and B cell development in the mouse.",
J Immunol, vol. 175, issue 6, pp. 3769-79, 2005 Sep 15.
"Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.",
J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
"Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.",
J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
"Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.",
J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.
"Emergence and evolution of functional heavy-chain antibodies in Camelidae.",
Dev Comp Immunol, vol. 27, issue 2, pp. 87-103, 2003 Feb.
"Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells.",
Immunology, vol. 109, issue 1, pp. 93-101, 2003 May.
"Efficient tumor targeting by single-domain antibody fragments of camels.",
Int J Cancer, vol. 98, issue 3, pp. 456-62, 2002 Mar 20.
"Heavy-chain antibodies in Camelidae; a case of evolutionary innovation.",
Immunogenetics, vol. 54, issue 1, pp. 39-47, 2002 Apr.
"Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.",
J Biol Chem, vol. 277, issue 26, pp. 23645-50, 2002 Jun 28.
"Functional heavy-chain antibodies in Camelidae.",
Adv Immunol, vol. 79, pp. 261-96, 2001.