Publications
Found 28 results
Filters: Keyword is Immunoglobulin Variable Region [Clear All Filters]
"Escape mechanisms of African trypanosomes: why trypanosomosis is keeping us awake.",
Parasitology, vol. 142, issue 3, pp. 417-27, 2015 Mar.
"Isolation of antigen-binding camelid heavy chain antibody fragments (nanobodies) from an immune library displayed on the surface of Pichia pastoris.",
J Biotechnol, vol. 145, issue 2, pp. 93-8, 2010 Jan 15.
"A novel promiscuous class of camelid single-domain antibody contributes to the antigen-binding repertoire.",
J Immunol, vol. 184, issue 10, pp. 5696-704, 2010 May 15.
"Substrate-dependent modulation of enzyme activity by allosteric effector antibodies.",
Biochim Biophys Acta, vol. 1794, issue 8, pp. 1259-68, 2009 Aug.
"Antibody technology in proteomics.",
Brief Funct Genomic Proteomic, vol. 7, issue 4, pp. 275-82, 2008 Jul.
"Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.",
J Mol Biol, vol. 377, issue 2, pp. 478-88, 2008 Mar 21.
"Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.",
J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
"Expression of a dromedary heavy chain-only antibody and B cell development in the mouse.",
J Immunol, vol. 175, issue 6, pp. 3769-79, 2005 Sep 15.
"Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.",
J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
"Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.",
J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
"Chemical basis for the affinity maturation of a camel single domain antibody.",
J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
"Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.",
J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.
"Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four Vlambda6 proteins.",
J Mol Recognit, vol. 17, issue 4, pp. 323-31, 2004 Jul-Aug.
"Emergence and evolution of functional heavy-chain antibodies in Camelidae.",
Dev Comp Immunol, vol. 27, issue 2, pp. 87-103, 2003 Feb.
"Heavy-chain antibodies in Camelidae; a case of evolutionary innovation.",
Immunogenetics, vol. 54, issue 1, pp. 39-47, 2002 Apr.
"Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.",
J Biol Chem, vol. 277, issue 26, pp. 23645-50, 2002 Jun 28.
"Degenerate interfaces in antigen-antibody complexes.",
J Mol Biol, vol. 313, issue 3, pp. 473-8, 2001 Oct 26.
"Functional heavy-chain antibodies in Camelidae.",
Adv Immunol, vol. 79, pp. 261-96, 2001.
"Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire.",
EMBO J, vol. 19, issue 5, pp. 921-30, 2000 Mar 1.
"Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?",
J Mol Biol, vol. 300, issue 1, pp. 83-91, 2000 Jun 30.
"Single domain antibodies: comparison of camel VH and camelised human VH domains.",
J Immunol Methods, vol. 231, issue 1-2, pp. 25-38, 1999 Dec 10.
"Isolation and characterization of single-chain Fv genes encoding antibodies specific for Drosophila Poxn protein.",
FEBS Lett, vol. 437, issue 1-2, pp. 75-80, 1998 Oct 16.
"Potent enzyme inhibitors derived from dromedary heavy-chain antibodies.",
EMBO J, vol. 17, issue 13, pp. 3512-20, 1998 Jul 1.
"The specific variable domain of camel heavy-chain antibodies is encoded in the germline.",
J Mol Biol, vol. 275, issue 3, pp. 413-8, 1998 Jan 23.
"Comparison of llama VH sequences from conventional and heavy chain antibodies.",
Mol Immunol, vol. 34, issue 16-17, pp. 1121-31, 1997 Nov-Dec.