Publications

Found 184 results
Filters: Keyword is Protein Binding  [Clear All Filters]
2018
Lee, S., Choi J., Mohanty J., Sousa L. P., Tome F., Pardon E., Steyaert J., Lemmon M. A., Lax I., and Schlessinger J., "Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.", Nature, vol. 553, issue 7689, pp. 501-505, 2018 01 25.
2017
Nguyen, H. Huy, Varadi M., Tompa P., and Pauwels K., "Affinity purification of human m-calpain through an intrinsically disordered inhibitor, calpastatin.", PLoS One, vol. 12, issue 3, pp. e0174125, 2017.
Schacherl, M., Gompert M., Pardon E., Lamkemeyer T., Steyaert J., and Baumann U., "Crystallographic and biochemical characterization of the dimeric architecture of site-2 protease.", Biochim Biophys Acta Biomembr, vol. 1859, issue 10, pp. 1859-1871, 2017 Oct.
Vandervelde, A., Drobnak I., Hadži S., Sterckx Y. G. - J., Welte T., De Greve H., Charlier D., Efremov R. G., Loris R., and Lah J., "Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.", Nucleic Acids Res, vol. 45, issue 6, pp. 2937-2950, 2017 Apr 07.
Manglik, A., Kobilka B. K., and Steyaert J., "Nanobodies to Study G Protein-Coupled Receptor Structure and Function.", Annu Rev Pharmacol Toxicol, vol. 57, pp. 19-37, 2017 01 06.
Talavera, A., Tamman H., Ainelo A., Hadǽi S., Garcia-Pino A., Hõrak R., Konijnenberg A., and Loris R., "Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 8, pp. 455-462, 2017 Aug 01.
Hadži, S., Garcia-Pino A., Haesaerts S., Jurenas D., Gerdes K., Lah J., and Loris R., "Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.", Nucleic Acids Res, vol. 45, issue 8, pp. 4972-4983, 2017 May 05.
Wohlkonig, A., Remaut H., Moune M., Tanina A., Meyer F., Desroses M., Steyaert J., Willand N., Baulard A. R., and Wintjens R., "Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.", Biochem Biophys Res Commun, vol. 487, issue 2, pp. 403-408, 2017 05 27.
Miller, P. S., Scott S., Masiulis S., De Colibus L., Pardon E., Steyaert J., and A Aricescu R., "Structural basis for GABA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
2016
Devree, B. T., Mahoney J. P., Vélez-Ruiz G. A., Rasmussen S. G. F., Kuszak A. J., Edwald E., Fung J-J., Manglik A., Masureel M., Du Y., et al., "Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.", Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.
Antonik, P. M., Volkov A. N., Broder U. N., Re D. Lo, van Nuland N. A. J., and Crowley P. B., "Anomer-Specific Recognition and Dynamics in a Fucose-Binding Lectin.", Biochemistry, vol. 55, issue 8, pp. 1195-203, 2016 Mar 01.
Jiang, X., Smirnova I., Kasho V., Wu J., Hirata K., Ke M., Pardon E., Steyaert J., Yan N., and H Kaback R., "Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.", Proc Natl Acad Sci U S A, vol. 113, issue 44, pp. 12420-12425, 2016 11 01.
Cho, K. Joon, Schepens B., Moonens K., Deng L., Fiers W., Remaut H., and Saelens X., "Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody.", J Virol, vol. 90, issue 1, pp. 611-5, 2016 01 01.
Guharoy, M., Bhowmick P., and Tompa P., "Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.", J Biol Chem, vol. 291, issue 13, pp. 6723-31, 2016 Mar 25.
Peyrassol, X., Laeremans T., Gouwy M., Lahura V., Debulpaep M., Van Damme J., Steyaert J., Parmentier M., and Langer I., "Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor.", J Immunol, vol. 196, issue 6, pp. 2893-901, 2016 Mar 15.
Egea-Jimenez, A. Luis, Gallardo R., Garcia-Pino A., Ivarsson Y., Wawrzyniak A. Maria, Kashyap R., Loris R., Schymkowitz J., Rousseau F., and Zimmermann P., "Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.", Nat Commun, vol. 7, pp. 12101, 2016 07 08.
Javaheri, A., Kruse T., Moonens K., Mejías-Luque R., Debraekeleer A., Asche C. I., Tegtmeyer N., Kalali B., Bach N. C., Sieber S. A., et al., "Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.", Nat Microbiol, vol. 2, pp. 16189, 2016 Oct 17.
Hristozova, N., Tompa P., and Kovacs D., "A Novel Method for Assessing the Chaperone Activity of Proteins.", PLoS One, vol. 11, issue 8, pp. e0161970, 2016.
Holt, P. J., Efremov R. G., Nakamaru-Ogiso E., and Sazanov L. A., "Reversible FMN dissociation from Escherichia coli respiratory complex I.", Biochim Biophys Acta, vol. 1857, issue 11, pp. 1777-1785, 2016 11.
Moonens, K., Gideonsson P., Subedi S., Bugaytsova J., Romão E., Mendez M., Nordén J., Fallah M., Rakhimova L., Shevtsova A., et al., "Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.", Cell Host Microbe, vol. 19, issue 1, pp. 55-66, 2016 Jan 13.
2015
Efremov, R. G., Leitner A., Aebersold R., and Raunser S., "Architecture and conformational switch mechanism of the ryanodine receptor.", Nature, vol. 517, issue 7532, pp. 39-43, 2015 Jan 01.
Zorzini, V., Buts L., Schrank E., Sterckx Y. G. J., Respondek M., Engelberg-Kulka H., Loris R., Zangger K., and van Nuland N. A. J., "Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.", Nucleic Acids Res, vol. 43, issue 2, pp. 1241-56, 2015 Jan.
Sounier, R., Mas C., Steyaert J., Laeremans T., Manglik A., Huang W., Kobilka B. K., Déméné H., and Granier S., "Propagation of conformational changes during μ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 375-8, 2015 Aug 20.
Moonens, K., Van den Broeck I., De Kerpel M., Deboeck F., Raymaekers H., Remaut H., and De Greve H., "Structural and functional insight into the carbohydrate receptor binding of F4 fimbriae-producing enterotoxigenic Escherichia coli.", J Biol Chem, vol. 290, issue 13, pp. 8409-19, 2015 Mar 27.
Volkov, A. N., "Structure and Function of Transient Encounters of Redox Proteins.", Acc Chem Res, vol. 48, issue 12, pp. 3036-43, 2015 Dec 15.

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