Publications

Found 145 results
Filters: Keyword is Protein Structure, Tertiary  [Clear All Filters]
2017
Schacherl, M., Gompert M., Pardon E., Lamkemeyer T., Steyaert J., and Baumann U., "Crystallographic and biochemical characterization of the dimeric architecture of site-2 protease.", Biochim Biophys Acta Biomembr, vol. 1859, issue 10, pp. 1859-1871, 2017 Oct.
Deyaert, E., Wauters L., Guaitoli G., Konijnenberg A., Leemans M., Terheyden S., Petrovic A., Gallardo R., Nederveen-Schippers L. M., Athanasopoulos P. S., et al., "A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover.", Nat Commun, vol. 8, issue 1, pp. 1008, 2017 10 18.
Barros-Álvarez, X., Kerchner K. M., Koh C. Yeow, Turley S., Pardon E., Steyaert J., Ranade R. M., J Gillespie R., Zhang Z., Verlinde C. L. M. J., et al., "Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.", Biochimie, vol. 138, pp. 124-136, 2017 Jul.
Manglik, A., Kobilka B. K., and Steyaert J., "Nanobodies to Study G Protein-Coupled Receptor Structure and Function.", Annu Rev Pharmacol Toxicol, vol. 57, pp. 19-37, 2017 01 06.
Pauwels, K., Lebrun P., and Tompa P., "To be disordered or not to be disordered: is that still a question for proteins in the cell?", Cell Mol Life Sci, vol. 74, issue 17, pp. 3185-3204, 2017 09.
2016
Piai, A., Calçada E. O., Tarenzi T., Del Grande A., Varadi M., Tompa P., Felli I. C., and Pierattelli R., "Just a Flexible Linker? The Structural and Dynamic Properties of CBP-ID4 Revealed by NMR Spectroscopy.", Biophys J, vol. 110, issue 2, pp. 372-81, 2016 Jan 19.
Van Laer, B., Roovers M., Wauters L., Kasprzak J. M., Dyzma M., Deyaert E., Singh R. Kumar, Feller A., Bujnicki J. M., Droogmans L., et al., "Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.", Nucleic Acids Res, vol. 44, issue 2, pp. 940-53, 2016 Jan 29.
2015
Efremov, R. G., Leitner A., Aebersold R., and Raunser S., "Architecture and conformational switch mechanism of the ryanodine receptor.", Nature, vol. 517, issue 7532, pp. 39-43, 2015 Jan 01.
Newman, J. A., Savitsky P., Allerston C. K., Bizard A. H., Özer Ö., Sarlós K., Liu Y., Pardon E., Steyaert J., Hickson I. D., et al., "Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.", Nucleic Acids Res, vol. 43, issue 10, pp. 5221-35, 2015 May 26.
Zorzini, V., Buts L., Schrank E., Sterckx Y. G. J., Respondek M., Engelberg-Kulka H., Loris R., Zangger K., and van Nuland N. A. J., "Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.", Nucleic Acids Res, vol. 43, issue 2, pp. 1241-56, 2015 Jan.
Verstraeten, N., Knapen W. Joris, Kint C. Ines, Liebens V., Van den Bergh B., Dewachter L., Michiels J. Elie, Fu Q., David C. Claudia, Fierro A. Carolina, et al., "Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.", Mol Cell, vol. 59, issue 1, pp. 9-21, 2015 Jul 02.
Huang, W., Manglik A., Venkatakrishnan A. J., Laeremans T., Feinberg E. N., Sanborn A. L., Kato H. E., Livingston K. E., Thorsen T. S., Kling R. C., et al., "Structural insights into µ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.
Rostislavleva, K., Soler N., Ohashi Y., Zhang L., Pardon E., Burke J. E., Masson G. R., Johnson C., Steyaert J., Ktistakis N. T., et al., "Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.", Science, vol. 350, issue 6257, pp. aac7365, 2015 Oct 09.
2014
Van Laer, K., Oliveira M., Wahni K., and Messens J., "The concerted action of a positive charge and hydrogen bonds dynamically regulates the pKa of the nucleophilic cysteine in the NrdH-redoxin family.", Protein Sci, vol. 23, issue 2, pp. 238-42, 2014 Feb.
De Gieter, S., Konijnenberg A., Talavera A., Butterer A., Haesaerts S., De Greve H., Sobott F., Loris R., and Garcia-Pino A., "The intrinsically disordered domain of the antitoxin Phd chaperones the toxin Doc against irreversible inactivation and misfolding.", J Biol Chem, vol. 289, issue 49, pp. 34013-23, 2014 Dec 05.
Garcia-Pino, A., Zenkin N., and Loris R., "The many faces of Fic: structural and functional aspects of Fic enzymes.", Trends Biochem Sci, vol. 39, issue 3, pp. 121-9, 2014 Mar.
Meusch, D., Gatsogiannis C., Efremov R. G., Lang A. E., Hofnagel O., Vetter I. R., Aktories K., and Raunser S., "Mechanism of Tc toxin action revealed in molecular detail.", Nature, vol. 508, issue 7494, pp. 61-5, 2014 Apr 03.
Lo, A. W. H., Moonens K., De Kerpel M., Brys L., Pardon E., Remaut H., and De Greve H., "The molecular mechanism of Shiga toxin Stx2e neutralization by a single-domain antibody targeting the cell receptor-binding domain.", J Biol Chem, vol. 289, issue 36, pp. 25374-81, 2014 Sep 05.
Bethuyne, J., De Gieter S., Zwaenepoel O., Garcia-Pino A., Durinck K., Verhelle A., Hassanzadeh-Ghassabeh G., Speleman F., Loris R., and Gettemans J., "A nanobody modulates the p53 transcriptional program without perturbing its functional architecture.", Nucleic Acids Res, vol. 42, issue 20, pp. 12928-38, 2014 Nov 10.
Denoncin, K., Vertommen D., Arts I. S., Goemans C. V., Rahuel-Clermont S., Messens J., and Collet J-F., "A new role for Escherichia coli DsbC protein in protection against oxidative stress.", J Biol Chem, vol. 289, issue 18, pp. 12356-64, 2014 May 02.
Polyansky, A. A., Chugunov A. O., Volynsky P. E., Krylov N. A., Nolde D. E., and Efremov R. G., "PREDDIMER: a web server for prediction of transmembrane helical dimers.", Bioinformatics, vol. 30, issue 6, pp. 889-90, 2014 Mar 15.
M Ceregido, A., Amilibia M. Spínola, Buts L., Rivera-Torres J., Garcia-Pino A., Bravo J., and van Nuland N. A. J., "The structure of TAX1BP1 UBZ1+2 provides insight into target specificity and adaptability.", J Mol Biol, vol. 426, issue 3, pp. 674-90, 2014 Feb 06.
Hubin, E., van Nuland N. A. J., Broersen K., and Pauwels K., "Transient dynamics of Aβ contribute to toxicity in Alzheimer's disease.", Cell Mol Life Sci, vol. 71, issue 18, pp. 3507-21, 2014 Sep.
2013
Kruse, A. C., Ring A. M., Manglik A., Hu J., Hu K., Eitel K., Hübner H., Pardon E., Valant C., Sexton P. M., et al., "Activation and allosteric modulation of a muscarinic acetylcholine receptor.", Nature, vol. 504, issue 7478, pp. 101-6, 2013 Dec 05.
Rocaboy, M., Herman R., Sauvage E., Remaut H., Moonens K., Terrak M., Charlier P., and Kerff F., "The crystal structure of the cell division amidase AmiC reveals the fold of the AMIN domain, a new peptidoglycan binding domain.", Mol Microbiol, vol. 90, issue 2, pp. 267-77, 2013 Oct.

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