Publications
Found 30 results
Filters: Keyword is Protein Structure, Tertiary and Author is Wyns, Lode [Clear All Filters]
"A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.",
J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
"Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic beta2-microglobulin variant.",
Proc Natl Acad Sci U S A, vol. 108, issue 4, pp. 1314-9, 2011 Jan 25.
"Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity.",
Cell, vol. 142, issue 1, pp. 101-11, 2010 Jul 9.
"Coupling of domain swapping to kinetic stability in a thioredoxin mutant.",
J Mol Biol, vol. 385, issue 5, pp. 1590-9, 2009 Feb 6.
"Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain.",
Mol Cell, vol. 35, issue 2, pp. 154-63, 2009 Jul 31.
"Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri.",
Biomol NMR Assign, vol. 3, issue 1, pp. 145-7, 2009 Jun.
"Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG.",
J Mol Biol, vol. 394, issue 5, pp. 957-67, 2009 Dec 18.
"Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation.",
J Biol Chem, vol. 283, issue 45, pp. 30821-7, 2008 Nov 7.
"Heterologous expression, purification and characterisation of the extracellular domain of trypanosome invariant surface glycoprotein ISG75.",
J Biotechnol, vol. 135, issue 3, pp. 247-54, 2008 Jun 30.
"Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex.",
PLoS One, vol. 3, issue 4, pp. e2040, 2008.
"Chloroplasts assemble the major subunit FaeG of Escherichia coli F4 (K88) fimbriae to strand-swapped dimers.",
J Mol Biol, vol. 368, issue 3, pp. 791-9, 2007 May 4.
"Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.",
Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
"Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.",
J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
"Crystallization and crystal manipulation of the Pterocarpus angolensis seed lectin.",
Acta Crystallogr D Biol Crystallogr, vol. 61, issue Pt 6, pp. 685-9, 2005 Jun.
"Crystallization of the C-terminal domain of the addiction antidote CcdA in complex with its toxin CcdB.",
Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 61, issue Pt 10, pp. 949-52, 2005 Oct 1.
"Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.",
Acta Crystallogr D Biol Crystallogr, vol. 61, issue Pt 8, pp. 1149-59, 2005 Aug.
"Molecular basis of gyrase poisoning by the addiction toxin CcdB.",
J Mol Biol, vol. 348, issue 5, pp. 1091-102, 2005 May 20.
"Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.",
J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.
"Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.",
J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
"Chemical basis for the affinity maturation of a camel single domain antibody.",
J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
"Crystallization of CcdB in complex with a GyrA fragment.",
Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 6, pp. 1132-4, 2004 Jun.
"Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.",
J Biol Chem, vol. 279, issue 2, pp. 1256-61, 2004 Jan 9.
"The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.",
Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 6, pp. 1180-4, 2004 Jun.
"A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.",
Nature, vol. 424, issue 6950, pp. 783-8, 2003 Aug 14.
"Crystal structure of the intrinsically flexible addiction antidote MazE.",
J Biol Chem, vol. 278, issue 30, pp. 28252-7, 2003 Jul 25.