Publications

Found 420 results
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2017
Ayoub, M. Akli, Crépieux P., Koglin M., Parmentier M., Pin J-P., Poupon A., Reiter E., Smit M., Steyaert J., Watier H., et al., "Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.", MAbs, vol. 9, issue 5, pp. 735-741, 2017 07.
Joncour, A., Desroy N., Housseman C., Bock X., Bienvenu N., Cherel L., Labeguere V., Peixoto C., Annoot D., Lepissier L., et al., "Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.", J Med Chem, vol. 60, issue 17, pp. 7371-7392, 2017 Sep 14.
Egea, J., Fabregat I., Frapart Y. M., Ghezzi P., Görlach A., Kietzmann T., Kubaichuk K., Knaus U. G., Lopez M. G., Olaso-Gonzalez G., et al., "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).", Redox Biol, vol. 13, pp. 94-162, 2017 10.
Moonens, K., and Remaut H., "Evolution and structural dynamics of bacterial glycan binding adhesins.", Curr Opin Struct Biol, vol. 44, pp. 48-58, 2017 06.
Peeters, K., Van Leemputte F., Fischer B., Bonini B. M., Quezada H., Tsytlonok M., Haesen D., Vanthienen W., Bernardes N., Gonzalez-Blas C. Bravo, et al., "Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras.", Nat Commun, vol. 8, issue 1, pp. 922, 2017 10 13.
Schenck, S., Kunz L., Sahlender D., Pardon E., Geertsma E. R., Savtchouk I., Suzuki T., Neldner Y., Štefanić S., Steyaert J., et al., "Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.", Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 08 01.
Efremov, R. G., Gatsogiannis C., and Raunser S., "Lipid Nanodiscs as a Tool for High-Resolution Structure Determination of Membrane Proteins by Single-Particle Cryo-EM.", Methods Enzymol, vol. 594, pp. 1-30, 2017.
Manglik, A., Kobilka B. K., and Steyaert J., "Nanobodies to Study G Protein-Coupled Receptor Structure and Function.", Annu Rev Pharmacol Toxicol, vol. 57, pp. 19-37, 2017 01 06.
Spaulding, C. N., Klein R. D., Ruer S., Kau A. L., Schreiber H. L., Cusumano Z. T., Dodson K. W., Pinkner J. S., Fremont D. H., Janetka J. W., et al., "Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.", Nature, vol. 546, issue 7659, pp. 528-532, 2017 06 22.
Abskharon, R., Dang J., Elfarash A., Wang Z., Shen P., Zou L. S., Hassan S., Wang F., Fujioka H., Steyaert J., et al., "Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors.", Microb Cell Fact, vol. 16, issue 1, pp. 170, 2017 Oct 04.
Singh, R. Kumar, Steyaert J., and Versées W., "Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis.", Protein Sci, vol. 26, issue 5, pp. 985-996, 2017 05.
Willegems, K., and Efremov R. G., "Structural Details of the Ryanodine Receptor Calcium Release Channel and Its Gating Mechanism.", Adv Exp Med Biol, vol. 981, pp. 179-204, 2017.
Schubert, A. F., Gladkova C., Pardon E., Wagstaff J. L., Freund S. M. V., Steyaert J., Maslen S. L., and Komander D., "Structure of PINK1 in complex with its substrate ubiquitin.", Nature, vol. 552, issue 7683, pp. 51-56, 2017 12 07.
2016
Odongo, S., Sterckx Y. G. J., Stijlemans B., Pillay D., Baltz T., Muyldermans S., and Magez S., "An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase.", PLoS Negl Trop Dis, vol. 10, issue 2, pp. e0004420, 2016 Feb.
Cho, K. Joon, Schepens B., Moonens K., Deng L., Fiers W., Remaut H., and Saelens X., "Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody.", J Virol, vol. 90, issue 1, pp. 611-5, 2016 01 01.
Peyrassol, X., Laeremans T., Gouwy M., Lahura V., Debulpaep M., Van Damme J., Steyaert J., Parmentier M., and Langer I., "Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor.", J Immunol, vol. 196, issue 6, pp. 2893-901, 2016 Mar 15.
Wijckmans, E., Nys M., Debaveye S., Brams M., Pardon E., Willegems K., Bertrand D., Steyaert J., Efremov R. G., and Ulens C., "Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.", PLoS One, vol. 11, issue 3, pp. e0151183, 2016.
Conover, M. S., Ruer S., Taganna J., Kalas V., De Greve H., Pinkner J. S., Dodson K. W., Remaut H., and Hultgren S. J., "Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection.", Cell Host Microbe, vol. 20, issue 4, pp. 482-492, 2016 Oct 12.
Fislage, M., Wauters L., and Versées W., "Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.", Biopolymers, vol. 105, issue 8, pp. 568-79, 2016 Aug.
Claes, K., Vandewalle K., Laukens B., Laeremans T., Vosters O., Langer I., Parmentier M., Steyaert J., and Callewaert N., "Modular Integrated Secretory System Engineering in Pichia pastoris To Enhance G-Protein Coupled Receptor Expression.", ACS Synth Biol, vol. 5, issue 10, pp. 1070-1075, 2016 10 21.
Zhan, Y-A., Abskharon R., Li Y., Yuan J., Zeng L., Dang J., Martinez M. Camacho, Wang Z., Mikol J., Lehmann S., et al., "Quiescin-sulfhydryl oxidase inhibits prion formation .", Aging (Albany NY), vol. 8, issue 12, pp. 3419-3429, 2016 12 11.
Fischer, B., Lüthy K., Paesmans J., De Koninck C., Maes I., Swerts J., Kuenen S., Uytterhoeven V., Verstreken P., and Versées W., "Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.", Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
Massa, S., Vikani N., Betti C., Ballet S., Vanderhaegen S., Steyaert J., Descamps B., Vanhove C., Bunschoten A., van Leeuwen F. W. B., et al., "Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.", Contrast Media Mol Imaging, vol. 11, issue 5, pp. 328-339, 2016 09.
Moonens, K., Gideonsson P., Subedi S., Bugaytsova J., Romão E., Mendez M., Nordén J., Fallah M., Rakhimova L., Shevtsova A., et al., "Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.", Cell Host Microbe, vol. 19, issue 1, pp. 55-66, 2016 Jan 13.
Blanchetot, C., De Jonge N., Desmyter A., Ongenae N., Hofman E., Klarenbeek A., Sadi A., Hultberg A., Kretz-Rommel A., Spinelli S., et al., "Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.", J Biol Chem, vol. 291, issue 26, pp. 13846-54, 2016 Jun 24.

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