Publications

Found 15 results
Filters: Keyword is Protein Stability  [Clear All Filters]
2016
Staus, D. P., Strachan R. T., Manglik A., Pani B., Kahsai A. W., Kim T. Hun, Wingler L. M., Ahn S., Chatterjee A., Masoudi A., et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
Wijckmans, E., Nys M., Debaveye S., Brams M., Pardon E., Willegems K., Bertrand D., Steyaert J., Efremov R. G., and Ulens C., "Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.", PLoS One, vol. 11, issue 3, pp. e0151183, 2016.
Pancsa, R., Varadi M., Tompa P., and Vranken W. F., "Start2Fold: a database of hydrogen/deuterium exchange data on protein folding and stability.", Nucleic Acids Res, vol. 44, issue D1, pp. D429-34, 2016 Jan 04.
Lafaye, C., Van Molle I., Dufe V. Tamu, Wahni K., Boudier A., Leroy P., Collet J-F., and Messens J., "Sulfur Denitrosylation by an Engineered Trx-like DsbG Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.", J Biol Chem, vol. 291, issue 29, pp. 15020-8, 2016 07 15.
2015
Wodak, S. J., Malevanets A., and Mackinnon S. S., "The Landscape of Intertwined Associations in Homooligomeric Proteins.", Biophys J, vol. 109, issue 6, pp. 1087-100, 2015 Sep 15.
Huang, W., Manglik A., Venkatakrishnan A. J., Laeremans T., Feinberg E. N., Sanborn A. L., Kato H. E., Livingston K. E., Thorsen T. S., Kling R. C., et al., "Structural insights into µ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.
2014
Smirnova, I., Kasho V., Jiang X., Pardon E., Steyaert J., and H Kaback R., "Outward-facing conformers of LacY stabilized by nanobodies.", Proc Natl Acad Sci U S A, vol. 111, issue 52, pp. 18548-53, 2014 Dec 30.
Abskharon, R. N. N., Giachin G., Wohlkonig A., Soror S. H., Pardon E., Legname G., and Steyaert J., "Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody.", J Am Chem Soc, vol. 136, issue 3, pp. 937-44, 2014 Jan 22.
2013
De Genst, E., Chan P-H., Pardon E., Hsu S-T. D., Kumita J. R., Christodoulou J., Menzer L., Chirgadze D. Y., Robinson C. V., Muyldermans S., et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
2012
Pellis, M., Pardon E., Zolghadr K., Rothbauer U., Vincke C., Kinne J., Dierynck I., Hertogs K., Leonhardt H., Messens J., et al., "A bacterial-two-hybrid selection system for one-step isolation of intracellularly functional Nanobodies.", Arch Biochem Biophys, vol. 526, issue 2, pp. 114-23, 2012 Oct 15.
Govaert, J., Pellis M., Deschacht N., Vincke C., Conrath K., Muyldermans S., and Saerens D., "Dual beneficial effect of interloop disulfide bond for single domain antibody fragments.", J Biol Chem, vol. 287, issue 3, pp. 1970-9, 2012 Jan 13.
2011
Steyaert, J., and Kobilka B. K., "Nanobody stabilization of G protein-coupled receptor conformational states.", Curr Opin Struct Biol, vol. 21, issue 4, pp. 567-72, 2011 Aug.
Roldan, J. L. Ortega, Blackledge M., van Nuland N. A. J., and Azuaga A. I., "Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP.", J Biomol NMR, vol. 50, issue 2, pp. 103-17, 2011 Jun.
Rasmussen, S. G. F., Choi H-J., Fung J. Jose, Pardon E., Casarosa P., Chae P. Seok, Devree B. T., Rosenbaum D. M., Thian F. Sun, Kobilka T. Sun, et al., "Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.", Nature, vol. 469, issue 7329, pp. 175-80, 2011 Jan 13.
2010
Roos, G., Geerlings P., and Messens J., "The conserved active site tryptophan of thioredoxin has no effect on its redox properties.", Protein Sci, vol. 19, issue 1, pp. 190-4, 2010 Jan.