Publications

Found 17 results
Filters: Keyword is Trypanosoma vivax  [Clear All Filters]
2015
Haynes, C. L. F., P. Ameloot, H. Remaut, N. Callewaert, Y. G. J. Sterckx, and S. Magez, "Production, purification and crystallization of a trans-sialidase from Trypanosoma vivax.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 5, pp. 577-85, 2015 May.
2014
La Greca, F., C. Haynes, B. Stijlemans, C. De Trez, and S. Magez, "Antibody-mediated control of Trypanosoma vivax infection fails in the absence of tumour necrosis factor.", Parasite Immunol, vol. 36, issue 6, pp. 271-6, 2014 Jun.
2012
Pellis, M., E. Pardon, K. Zolghadr, U. Rothbauer, C. Vincke, J. Kinne, I. Dierynck, K. Hertogs, H. Leonhardt, J. Messens, et al., "A bacterial-two-hybrid selection system for one-step isolation of intracellularly functional Nanobodies.", Arch Biochem Biophys, vol. 526, issue 2, pp. 114-23, 2012 Oct 15.
2009
Versées, W., A. Goeminne, M. Berg, A. Vandemeulebroucke, A. Haemers, K. Augustyns, and J. Steyaert, "Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.", Biochim Biophys Acta, vol. 1794, issue 6, pp. 953-60, 2009 Jun.
Barlow, J. N., K. Conrath, and J. Steyaert, "Substrate-dependent modulation of enzyme activity by allosteric effector antibodies.", Biochim Biophys Acta, vol. 1794, issue 8, pp. 1259-68, 2009 Aug.
2008
Vandemeulebroucke, A., S. De Vos, E. Van Holsbeke, J. Steyaert, and W. Versées, "A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.", J Biol Chem, vol. 283, issue 32, pp. 22272-82, 2008 Aug 08.
Goeminne, A., M. Berg, M. McNaughton, G. Bal, G. Surpateanu, P. Van der Veken, S. De Prol, W. Versées, J. Steyaert, A. Haemers, et al., "N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.", Bioorg Med Chem, vol. 16, issue 14, pp. 6752-63, 2008 Jul 15.
Goeminne, A., M. McNaughton, G. Bal, G. Surpateanu, P. Van der Veken, S. De Prol, W. Versées, J. Steyaert, A. Haemers, and K. Augustyns, "Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors.", Eur J Med Chem, vol. 43, issue 2, pp. 315-26, 2008 Feb.
2007
Barlow, J. N., and J. Steyaert, "Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax.", Biochim Biophys Acta, vol. 1774, issue 11, pp. 1451-61, 2007 Nov.
2006
Vandemeulebroucke, A., W. Versées, J. Steyaert, and J. N. Barlow, "Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry.", Biochemistry, vol. 45, issue 30, pp. 9307-18, 2006 Aug 01.
Versées, W., J. Barlow, and J. Steyaert, "Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis.", J Mol Biol, vol. 359, issue 2, pp. 331-46, 2006 Jun 2.
2005
Loverix, S., P. Geerlings, M. McNaughton, K. Augustyns, A. Vandemeulebroucke, J. Steyaert, and W. Versées, "Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage.", J Biol Chem, vol. 280, issue 15, pp. 14799-802, 2005 Apr 15.
Ranquin, A., W. Versées, W. Meier, J. Steyaert, and P. Van Gelder, "Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system.", Nano Lett, vol. 5, issue 11, pp. 2220-4, 2005 Nov.
2004
Versées, W., S. Loverix, A. Vandemeulebroucke, P. Geerlings, and J. Steyaert, "Leaving group activation by aromatic stacking: an alternative to general acid catalysis.", J Mol Biol, vol. 338, issue 1, pp. 1-6, 2004 Apr 16.
2003
Vandemeulebroucke, A., W. Versées, S. De Vos, E. Van Holsbeke, and J. Steyaert, "Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release.", Biochemistry, vol. 42, issue 44, pp. 12902-8, 2003 Nov 11.
2002
Versées, W., K. Decanniere, E. Van Holsbeke, N. Devroede, and J. Steyaert, "Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.", J Biol Chem, vol. 277, issue 18, pp. 15938-46, 2002 May 03.
2001
Versées, W., K. Decanniere, R. Pellé, J. Depoorter, E. Brosens, D. W. Parkin, and J. Steyaert, "Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.", J Mol Biol, vol. 307, issue 5, pp. 1363-79, 2001 Apr 13.