Publications

Found 41 results
Filters: Keyword is Trypanosoma brucei brucei  [Clear All Filters]
2015
Cnops, J., Magez S., and De Trez C., "Escape mechanisms of African trypanosomes: why trypanosomosis is keeping us awake.", Parasitology, vol. 142, issue 3, pp. 417-27, 2015 Mar.
De Trez, C., Katsandegwaza B., Caljon G., and Magez S., "Experimental African Trypanosome Infection by Needle Passage or Natural Tsetse Fly Challenge Thwarts the Development of Collagen-Induced Arthritis in DBA/1 Prone Mice via an Impairment of Antigen Specific B Cell Autoantibody Titers.", PLoS One, vol. 10, issue 6, pp. e0130431, 2015.
Stijlemans, B., Beschin A., Magez S., Van Ginderachter J. A., and De Baetselier P., "Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron.", Biomed Res Int, vol. 2015, pp. 819389, 2015.
Arias, J. L., Unciti-Broceta J. D., Maceira J., Del Castillo T., Hernández-Quero J., Magez S., Soriano M., and Garcia-Salcedo J. A., "Nanobody conjugated PLGA nanoparticles for active targeting of African Trypanosomiasis.", J Control Release, vol. 197, pp. 190-8, 2015 Jan 10.
2014
Del Castillo, T., Marales-Sanfrutos J., Santoyo-González F., Magez S., F Lopez-Jaramillo J., and Garcia-Salcedo J. A., "Monovinyl sulfone β-cyclodextrin. A flexible drug carrier system.", ChemMedChem, vol. 9, issue 2, pp. 383-9, 2014 Feb.
2012
Salmon, D., Vanwalleghem G., Morias Y., Denoeud J., Krumbholz C., Lhommé F., Bachmaier S., Kador M., Gossmann J., Dias F. Braga Steh, et al., "Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host.", Science, vol. 337, issue 6093, pp. 463-6, 2012 Jul 27.
Caljon, G., Stijlemans B., Saerens D., Van Den Abbeele J., Muyldermans S., Magez S., and De Baetselier P., "Affinity is an important determinant of the anti-trypanosome activity of nanobodies.", PLoS Negl Trop Dis, vol. 6, issue 11, pp. e1902, 2012.
Park, Y-J., Budiarto T., Wu M., Pardon E., Steyaert J., and Hol W. G. J., "The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.", Nucleic Acids Res, vol. 40, issue 14, pp. 6966-77, 2012 Aug.
Caljon, G., Caveliers V., Lahoutte T., Stijlemans B., Ghassabeh G. H., Van Den Abbeele J., Smolders I., De Baetselier P., Michotte Y., Muyldermans S., et al., "Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier.", Br J Pharmacol, vol. 165, issue 7, pp. 2341-53, 2012 Apr.
2011
Stijlemans, B., Caljon G., Natesan S. Kumar A., Saerens D., Conrath K., Pérez-Morga D., Skepper J. N., Nikolaou A., Brys L., Pays E., et al., "High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.", PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
Wu, M., Park Y-J., Pardon E., Turley S., Hayhurst A., Deng J., Steyaert J., and Hol W. G. J., "Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.", J Struct Biol, vol. 174, issue 1, pp. 124-36, 2011 Apr.
Bockstal, V., Guirnalda P., Caljon G., Goenka R., Telfer J. C., Frenkel D., Radwanska M., Magez S., and Black S. J., "T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis.", PLoS Pathog, vol. 7, issue 6, pp. e1002089, 2011 Jun.
2010
Berg, M., Kohl L., Van der Veken P., Joossens J., Al-Salabi M. I., Castagna V., Giannese F., Cos P., Versées W., Steyaert J., et al., "Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis.", Antimicrob Agents Chemother, vol. 54, issue 5, pp. 1900-8, 2010 May.
Stijlemans, B., Vankrunkelsven A., Brys L., Raes G., Magez S., and De Baetselier P., "Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis.", Microbes Infect, vol. 12, issue 5, pp. 389-99, 2010 May.
Vandemeulebroucke, A., Minici C., Bruno I., Muzzolini L., Tornaghi P., Parkin D. W., Versées W., Steyaert J., and Degano M., "Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei.", Biochemistry, vol. 49, issue 41, pp. 8999-9010, 2010 Oct 19.
2008
Tran, T., Büscher P., Vandenbussche G., Wyns L., Messens J., and De Greve H., "Heterologous expression, purification and characterisation of the extracellular domain of trypanosome invariant surface glycoprotein ISG75.", J Biotechnol, vol. 135, issue 3, pp. 247-54, 2008 Jun 30.
Magez, S., Schwegmann A., Atkinson R., Claes F., Drennan M., De Baetselier P., and Brombacher F., "The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice.", PLoS Pathog, vol. 4, issue 8, pp. e1000122, 2008.
Stijlemans, B., Vankrunkelsven A., Brys L., Magez S., and De Baetselier P., "Role of iron homeostasis in trypanosomiasis-associated anemia.", Immunobiology, vol. 213, issue 9-10, pp. 823-35, 2008.
Radwanska, M., Guirnalda P., De Trez C., Ryffel B., Black S., and Magez S., "Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses.", PLoS Pathog, vol. 4, issue 5, pp. e1000078, 2008 May.
2007
Goeminne, A., McNaughton M., Bal G., Surpateanu G., Van der Veken P., De Prol S., Versées W., Steyaert J., Apers S., Haemers A., et al., "1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors.", Bioorg Med Chem Lett, vol. 17, issue 9, pp. 2523-6, 2007 May 1.
Stijlemans, B., Baral T. Nath, Guilliams M., Brys L., Korf J., Drennan M., Van Den Abbeele J., De Baetselier P., and Magez S., "A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology.", J Immunol, vol. 179, issue 6, pp. 4003-14, 2007 Sep 15.
Semballa, S., Okomo-Assoumou M. C., Holzmuller P., Büscher P., Magez S., Lemesre J. L., Daulouede S., Courtois P., Geffard M., and Vincendeau P., "Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes.", Exp Parasitol, vol. 115, issue 2, pp. 173-80, 2007 Feb.
Barkhuizen, M., Magez S., Atkinson R. A., and Brombacher F., "Interleukin-12p70-dependent interferon- gamma production is crucial for resistance in African trypanosomiasis.", J Infect Dis, vol. 196, issue 8, pp. 1253-60, 2007 Oct 15.
2006
Caljon, G., Van Den Abbeele J., Stijlemans B., Coosemans M., De Baetselier P., and Magez S., "Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response.", Infect Immun, vol. 74, issue 11, pp. 6324-30, 2006 Nov.
2005
Drennan, M. B., Stijlemans B., Van Den Abbeele J., Quesniaux V. J., Barkhuizen M., Brombacher F., De Baetselier P., Ryffel B., and Magez S., "The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent.", J Immunol, vol. 175, issue 4, pp. 2501-9, 2005 Aug 15.

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