Publications
Found 35 results
Filters: Keyword is Mice and Author is Patrick De Baetselier [Clear All Filters]
"High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.",
PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
"In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/micro-CT.",
J Nucl Med, vol. 51, issue 7, pp. 1099-106, 2010 Jul.
"Nanobodies as tools for in vivo imaging of specific immune cell types.",
J Nucl Med, vol. 51, issue 5, pp. 782-9, 2010 May.
"A novel promiscuous class of camelid single-domain antibody contributes to the antigen-binding repertoire.",
J Immunol, vol. 184, issue 10, pp. 5696-704, 2010 May 15.
"Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis.",
Microbes Infect, vol. 12, issue 5, pp. 389-99, 2010 May.
"Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens.",
J Immunol Methods, vol. 329, issue 1-2, pp. 138-50, 2008 Jan 1.
"The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice.",
PLoS Pathog, vol. 4, issue 8, pp. e1000122, 2008.
"Role of iron homeostasis in trypanosomiasis-associated anemia.",
Immunobiology, vol. 213, issue 9-10, pp. 823-35, 2008.
"Control of Trypanosoma evansi infection is IgM mediated and does not require a type I inflammatory response.",
J Infect Dis, vol. 195, issue 10, pp. 1513-20, 2007 May 15.
"A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology.",
J Immunol, vol. 179, issue 6, pp. 4003-14, 2007 Sep 15.
"Tumor necrosis factor (TNF) receptor-1 (TNFp55) signal transduction and macrophage-derived soluble TNF are crucial for nitric oxide-mediated Trypanosoma congolense parasite killing.",
J Infect Dis, vol. 196, issue 6, pp. 954-62, 2007 Sep 15.
"Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.",
Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
"Interferon-gamma and nitric oxide in combination with antibodies are key protective host immune factors during trypanosoma congolense Tc13 Infections.",
J Infect Dis, vol. 193, issue 11, pp. 1575-83, 2006 Jun 1.
"Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response.",
Infect Immun, vol. 74, issue 11, pp. 6324-30, 2006 Nov.
"Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment.",
Int J Parasitol, vol. 36, issue 9, pp. 1025-35, 2006 Aug.
"The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent.",
J Immunol, vol. 175, issue 4, pp. 2501-9, 2005 Aug 15.
"Efficient cancer therapy with a nanobody-based conjugate.",
Cancer Res, vol. 64, issue 8, pp. 2853-7, 2004 Apr 15.
"P75 tumor necrosis factor-receptor shedding occurs as a protective host response during African trypanosomiasis.",
J Infect Dis, vol. 189, issue 3, pp. 527-39, 2004 Feb 1.
"Control of experimental Trypanosoma brucei infections occurs independently of lymphotoxin-alpha induction.",
Infect Immun, vol. 70, issue 3, pp. 1342-51, 2002 Mar.
"Efficient tumor targeting by single-domain antibody fragments of camels.",
Int J Cancer, vol. 98, issue 3, pp. 456-62, 2002 Mar 20.
"Selective pressure can influence the resistance of Trypanosoma congolense to normal human serum.",
Exp Parasitol, vol. 102, issue 2, pp. 61-5, 2002 Oct.
"A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.",
J Biol Chem, vol. 276, issue 36, pp. 33458-64, 2001 Sep 7.
"Trypanosoma brucei brucei infection impairs MHC class II antigen presentation capacity of macrophages.",
Parasite Immunol, vol. 22, issue 7, pp. 361-70, 2000 Jul.
"Convergent evolution of cytokines.",
Nature, vol. 400, issue 6745, pp. 627-8, 1999 Aug 12.
"Hemozoin is a key factor in the induction of malaria-associated immunosuppression.",
Parasite Immunol, vol. 21, issue 11, pp. 545-54, 1999 Nov.