Publications

Found 31 results
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2017
Joncour, A., N. Desroy, C. Housseman, X. Bock, N. Bienvenu, L. Cherel, V. Labeguere, C. Peixoto, D. Annoot, L. Lepissier, et al., "Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.", J Med Chem, vol. 60, issue 17, pp. 7371-7392, 2017 Sep 14.
Schenck, S., L. Kunz, D. Sahlender, E. Pardon, E. R. Geertsma, I. Savtchouk, T. Suzuki, Y. Neldner, S. Štefanić, J. Steyaert, et al., "Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.", Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 08 01.
2013
Jiang, J-X., K. J. Aitken, C. Sotiropoulos, C. Sotiropolous, T. Kirwan, T. Panchal, N. Zhang, S. Pu, S. J. Wodak, C. Tolg, et al., "Phenotypic switching induced by damaged matrix is associated with DNA methyltransferase 3A (DNMT3A) activity and nuclear localization in smooth muscle cells (SMC).", PLoS One, vol. 8, issue 8, pp. e69089, 2013.
Xavier, C., I. Vaneycken, M. D'huyvetter, J. Heemskerk, M. Keyaerts, C. Vincke, N. Devoogdt, S. Muyldermans, T. Lahoutte, and V. Caveliers, "Synthesis, preclinical validation, dosimetry, and toxicity of 68Ga-NOTA-anti-HER2 Nanobodies for iPET imaging of HER2 receptor expression in cancer.", J Nucl Med, vol. 54, issue 5, pp. 776-84, 2013 May.
2012
Hmila, I., B. Cosyns, H. Tounsi, B. Roosens, V. Caveliers, R. Ben Abderrazek, S. Boubaker, S. Muyldermans, M. El Ayeb, B. Bouhaouala-Zahar, et al., "Pre-clinical studies of toxin-specific nanobodies: evidence of in vivo efficacy to prevent fatal disturbances provoked by scorpion envenoming.", Toxicol Appl Pharmacol, vol. 264, issue 2, pp. 222-31, 2012 Oct 15.
Caljon, G., V. Caveliers, T. Lahoutte, B. Stijlemans, G. H. Ghassabeh, J. Van Den Abbeele, I. Smolders, P. De Baetselier, Y. Michotte, S. Muyldermans, et al., "Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier.", Br J Pharmacol, vol. 165, issue 7, pp. 2341-53, 2012 Apr.
2011
Rasmussen, S. G. F., B. T. Devree, Y. Zou, A. C. Kruse, K. Young Chung, T. Sun Kobilka, F. Sun Thian, P. Seok Chae, E. Pardon, D. Calinski, et al., "Crystal structure of the β2 adrenergic receptor-Gs protein complex.", Nature, vol. 477, issue 7366, pp. 549-55, 2011 Sep 29.
2010
De Vocht, C., A. Ranquin, J. Van Ginderachter, T. Vanhaecke, V. Rogiers, P. Van Gelder, W. Versées, and J. Steyaert, "Polymeric nanoreactors for enzyme replacement therapy of MNGIE.", J Control Release, vol. 148, issue 1, pp. e19-20, 2010 Nov 20.
2009
De Vocht, C., A. Ranquin, R. Willaert, J. A. Van Ginderachter, T. Vanhaecke, V. Rogiers, W. Versées, P. Van Gelder, and J. Steyaert, "Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.", J Control Release, vol. 137, issue 3, pp. 246-54, 2009 Aug 4.
Balázs, A., V. Csizmok, L. Buday, M. Rakács, R. Kiss, M. Bokor, R. Udupa, K. Tompa, and P. Tompa, "High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1.", FEBS J, vol. 276, issue 14, pp. 3744-56, 2009 Jul.
2005
Bozoky, Z., A. Alexa, P. Tompa, and P. Friedrich, "Multiple interactions of the 'transducer' govern its function in calpain activation by Ca2+.", Biochem J, vol. 388, issue Pt 3, pp. 741-4, 2005 Jun 15.
Csizmok, V., M. Bokor, P. Bánki, E. Klement, K. F. Medzihradszky, P. Friedrich, K. Tompa, and P. Tompa, "Primary contact sites in intrinsically unstructured proteins: the case of calpastatin and microtubule-associated protein 2.", Biochemistry, vol. 44, issue 10, pp. 3955-64, 2005 Mar 15.
2004
Alexa, A., Z. Bozoky, A. Farkas, P. Tompa, and P. Friedrich, "Contribution of distinct structural elements to activation of calpain by Ca2+ ions.", J Biol Chem, vol. 279, issue 19, pp. 20118-26, 2004 May 7.
Friedrich, P., H. Papp, K. Halasy, A. Farkas, B. Farkas, P. Tompa, and P. Kása, "Differential distribution of calpain small subunit 1 and 2 in rat brain.", Eur J Neurosci, vol. 19, issue 7, pp. 1819-25, 2004 Apr.
2003
Mucsi, Z., F. Hudecz, M. Hollósi, P. Tompa, and P. Friedrich, "Binding-induced folding transitions in calpastatin subdomains A and C.", Protein Sci, vol. 12, issue 10, pp. 2327-36, 2003 Oct.
2002
Tompa, P., Z. Mucsi, G. Orosz, and P. Friedrich, "Calpastatin subdomains A and C are activators of calpain.", J Biol Chem, vol. 277, issue 11, pp. 9022-6, 2002 Mar 15.
Ogata, K., and S. J. Wodak, "Conserved water molecules in MHC class-I molecules and their putative structural and functional roles.", Protein Eng, vol. 15, issue 8, pp. 697-705, 2002 Aug.
Schad, E., A. Farkas, G. Jékely, P. Tompa, and P. Friedrich, "A novel human small subunit of calpains.", Biochem J, vol. 362, issue Pt 2, pp. 383-8, 2002 Mar 1.
Alexa, A., G. Schmidt, P. Tompa, S. Ogueta, J. Vázquez, P. Kulcsár, J. Kovács, V. Dombrádi, and P. Friedrich, "The phosphorylation state of threonine-220, a uniquely phosphatase-sensitive protein kinase A site in microtubule-associated protein MAP2c, regulates microtubule binding and stability.", Biochemistry, vol. 41, issue 41, pp. 12427-35, 2002 Oct 15.
2001
Tompa, P., Y. Emori, H. Sorimachi, K. Suzuki, and P. Friedrich, "Domain III of calpain is a ca2+-regulated phospholipid-binding domain.", Biochem Biophys Res Commun, vol. 280, issue 5, pp. 1333-9, 2001 Feb 9.
1999
Gupta, V., S. Muyldermans, L. Wyns, and D. M. Salunke, "The crystal structure of recombinant rat pancreatic RNase A.", Proteins, vol. 35, issue 1, pp. 1-12, 1999 Apr 1.
Nguyen, V. K., R. Hamers, L. Wyns, and S. Muyldermans, "Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies.", Mol Immunol, vol. 36, issue 8, pp. 515-24, 1999 Jun.
1996
Alexa, A., P. Tompa, A. Baki, G. Vereb, and P. Friedrich, "Mutual protection of microtubule-associated protein 2 (MAP2) and cyclic AMP-dependent protein kinase II against mu-calpain.", J Neurosci Res, vol. 44, issue 5, pp. 438-45, 1996 Jun 1.
Sánchez, C., P. Tompa, K. Szücs, P. Friedrich, and J. Avila, "Phosphorylation and dephosphorylation in the proline-rich C-terminal domain of microtubule-associated protein 2.", Eur J Biochem, vol. 241, issue 3, pp. 765-71, 1996 Nov 1.
1995
Tompa, P., E. Schád, A. Baki, A. Alexa, J. Batke, and P. Friedrich, "An ultrasensitive, continuous fluorometric assay for calpain activity.", Anal Biochem, vol. 228, issue 2, pp. 287-93, 1995 Jul 1.

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