Publications
Found 24 results
Filters: Keyword is Trypanosomiasis, African and Author is Patrick De Baetselier [Clear All Filters]
"Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier.",
Br J Pharmacol, vol. 165, issue 7, pp. 2341-53, 2012 Apr.
"High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.",
PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
"The central role of macrophages in trypanosomiasis-associated anemia: rationale for therapeutical approaches.",
Endocr Metab Immune Disord Drug Targets, vol. 10, issue 1, pp. 71-82, 2010 Mar.
"Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis.",
Microbes Infect, vol. 12, issue 5, pp. 389-99, 2010 May.
"The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice.",
PLoS Pathog, vol. 4, issue 8, pp. e1000122, 2008.
"Role of iron homeostasis in trypanosomiasis-associated anemia.",
Immunobiology, vol. 213, issue 9-10, pp. 823-35, 2008.
"African trypanosomosis: from immune escape and immunopathology to immune intervention.",
Vet Parasitol, vol. 148, issue 1, pp. 3-13, 2007 Aug 19.
"A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology.",
J Immunol, vol. 179, issue 6, pp. 4003-14, 2007 Sep 15.
"Tumor necrosis factor (TNF) receptor-1 (TNFp55) signal transduction and macrophage-derived soluble TNF are crucial for nitric oxide-mediated Trypanosoma congolense parasite killing.",
J Infect Dis, vol. 196, issue 6, pp. 954-62, 2007 Sep 15.
"Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.",
Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
"[Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor].",
Med Sci (Paris), vol. 22, issue 11, pp. 914-6, 2006 Nov.
"Interferon-gamma and nitric oxide in combination with antibodies are key protective host immune factors during trypanosoma congolense Tc13 Infections.",
J Infect Dis, vol. 193, issue 11, pp. 1575-83, 2006 Jun 1.
"Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response.",
Infect Immun, vol. 74, issue 11, pp. 6324-30, 2006 Nov.
"The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent.",
J Immunol, vol. 175, issue 4, pp. 2501-9, 2005 Aug 15.
"P75 tumor necrosis factor-receptor shedding occurs as a protective host response during African trypanosomiasis.",
J Infect Dis, vol. 189, issue 3, pp. 527-39, 2004 Feb 1.
"Control of experimental Trypanosoma brucei infections occurs independently of lymphotoxin-alpha induction.",
Infect Immun, vol. 70, issue 3, pp. 1342-51, 2002 Mar.
"Selective pressure can influence the resistance of Trypanosoma congolense to normal human serum.",
Exp Parasitol, vol. 102, issue 2, pp. 61-5, 2002 Oct.
"The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense.",
Am J Trop Med Hyg, vol. 67, issue 6, pp. 684-90, 2002 Dec.
"Trypanosoma brucei brucei infection impairs MHC class II antigen presentation capacity of macrophages.",
Parasite Immunol, vol. 22, issue 7, pp. 361-70, 2000 Jul.
"Tumor necrosis factor alpha is a key mediator in the regulation of experimental Trypanosoma brucei infections.",
Infect Immun, vol. 67, issue 6, pp. 3128-32, 1999 Jun.
"The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors.",
J Immunol, vol. 160, issue 4, pp. 1949-56, 1998 Feb 15.
"Trypanosoma brucei infection elicits nitric oxide-dependent and nitric oxide-independent suppressive mechanisms.",
J Leukoc Biol, vol. 63, issue 4, pp. 429-39, 1998 Apr.
"Murine tumour necrosis factor plays a protective role during the initial phase of the experimental infection with Trypanosoma brucei brucei.",
Parasite Immunol, vol. 15, issue 11, pp. 635-41, 1993 Nov.
"A role for TNF during African trypanosomiasis: involvement in parasite control, immunosuppression and pathology.",
Res Immunol, vol. 144, issue 5, pp. 370-6, 1993 Jun.