Publications

Found 347 results
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2017
Rosado, L. Astolfi, Wahni K., Degiacomi G., Pedre B., Young D., de la Rubia A. G., Boldrin F., Martens E., Marcos-Pascual L., Sancho-Vaello E., et al., "The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of .", J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 08 11.
Schenck, S., Kunz L., Sahlender D., Pardon E., Geertsma E. R., Savtchouk I., Suzuki T., Neldner Y., Štefanić S., Steyaert J., et al., "Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.", Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 08 01.
Barros-Álvarez, X., Kerchner K. M., Koh C. Yeow, Turley S., Pardon E., Steyaert J., Ranade R. M., J Gillespie R., Zhang Z., Verlinde C. L. M. J., et al., "Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.", Biochimie, vol. 138, pp. 124-136, 2017 Jul.
Efremov, R. G., Gatsogiannis C., and Raunser S., "Lipid Nanodiscs as a Tool for High-Resolution Structure Determination of Membrane Proteins by Single-Particle Cryo-EM.", Methods Enzymol, vol. 594, pp. 1-30, 2017.
Deyaert, E., Kortholt A., and Versées W., "The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 9, pp. 520-524, 2017 Sep 01.
Vandervelde, A., Drobnak I., Hadži S., Sterckx Y. G. - J., Welte T., De Greve H., Charlier D., Efremov R. G., Loris R., and Lah J., "Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.", Nucleic Acids Res, vol. 45, issue 6, pp. 2937-2950, 2017 Apr 07.
Spaulding, C. N., Klein R. D., Ruer S., Kau A. L., Schreiber H. L., Cusumano Z. T., Dodson K. W., Pinkner J. S., Fremont D. H., Janetka J. W., et al., "Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.", Nature, vol. 546, issue 7659, pp. 528-532, 2017 06 22.
Sormanni, P., Piovesan D., Heller G. T., Bonomi M., Kukic P., Camilloni C., Fuxreiter M., Dosztányi Z., Pappu R. V., M Babu M., et al., "Simultaneous quantification of protein order and disorder.", Nat Chem Biol, vol. 13, issue 4, pp. 339-342, 2017 03 22.
Miller, P. S., Scott S., Masiulis S., De Colibus L., Pardon E., Steyaert J., and A Aricescu R., "Structural basis for GABA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
Schubert, A. F., Gladkova C., Pardon E., Wagstaff J. L., Freund S. M. V., Steyaert J., Maslen S. L., and Komander D., "Structure of PINK1 in complex with its substrate ubiquitin.", Nature, vol. 552, issue 7683, pp. 51-56, 2017 12 07.
2016
Devree, B. T., Mahoney J. P., Vélez-Ruiz G. A., Rasmussen S. G. F., Kuszak A. J., Edwald E., Fung J-J., Manglik A., Masureel M., Du Y., et al., "Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.", Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.
Staus, D. P., Strachan R. T., Manglik A., Pani B., Kahsai A. W., Kim T. Hun, Wingler L. M., Ahn S., Chatterjee A., Masoudi A., et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
Antonik, P. M., Volkov A. N., Broder U. N., Re D. Lo, van Nuland N. A. J., and Crowley P. B., "Anomer-Specific Recognition and Dynamics in a Fucose-Binding Lectin.", Biochemistry, vol. 55, issue 8, pp. 1195-203, 2016 Mar 01.
Pancsa, R., and Tompa P., "Coding Regions of Intrinsic Disorder Accommodate Parallel Functions.", Trends Biochem Sci, vol. 41, issue 11, pp. 898-906, 2016 Nov.
Jiang, X., Smirnova I., Kasho V., Wu J., Hirata K., Ke M., Pardon E., Steyaert J., Yan N., and H Kaback R., "Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.", Proc Natl Acad Sci U S A, vol. 113, issue 44, pp. 12420-12425, 2016 11 01.
Egea-Jimenez, A. Luis, Gallardo R., Garcia-Pino A., Ivarsson Y., Wawrzyniak A. Maria, Kashyap R., Loris R., Schymkowitz J., Rousseau F., and Zimmermann P., "Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.", Nat Commun, vol. 7, pp. 12101, 2016 07 08.
Fischer, B., Lüthy K., Paesmans J., De Koninck C., Maes I., Swerts J., Kuenen S., Uytterhoeven V., Verstreken P., and Versées W., "Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.", Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
Van Laer, B., Roovers M., Wauters L., Kasprzak J. M., Dyzma M., Deyaert E., Singh R. Kumar, Feller A., Bujnicki J. M., Droogmans L., et al., "Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.", Nucleic Acids Res, vol. 44, issue 2, pp. 940-53, 2016 Jan 29.
Moonens, K., Gideonsson P., Subedi S., Bugaytsova J., Romão E., Mendez M., Nordén J., Fallah M., Rakhimova L., Shevtsova A., et al., "Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.", Cell Host Microbe, vol. 19, issue 1, pp. 55-66, 2016 Jan 13.
Guaitoli, G., Raimondi F., Gilsbach B. K., Gómez-Llorente Y., Deyaert E., Renzi F., Li X., Schaffner A., Jagtap P. Kumar Anku, Boldt K., et al., "Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.", Proc Natl Acad Sci U S A, vol. 113, issue 30, pp. E4357-66, 2016 07 26.
Zorzini, V., Mernik A., Lah J., Sterckx Y. G. J., De Jonge N., Garcia-Pino A., De Greve H., Versées W., and Loris R., "Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.", J Biol Chem, vol. 291, issue 21, pp. 10950-60, 2016 May 20.
Lafaye, C., Van Molle I., Dufe V. Tamu, Wahni K., Boudier A., Leroy P., Collet J-F., and Messens J., "Sulfur Denitrosylation by an Engineered Trx-like DsbG Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.", J Biol Chem, vol. 291, issue 29, pp. 15020-8, 2016 07 15.
Guharoy, M., Bhowmick P., Sallam M., and Tompa P., "Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.", Nat Commun, vol. 7, pp. 10239, 2016 Jan 06.

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