Publications

Found 336 results
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2017
Rosado, L. Astolfi, Wahni K., Degiacomi G., Pedre B., Young D., de la Rubia A. G., Boldrin F., Martens E., Marcos-Pascual L., Sancho-Vaello E., et al., "The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.", J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 Aug 11.
Schenck, S., Kunz L., Sahlender D., Pardon E., Geertsma E. R., Savtchouk I., Suzuki T., Neldner Y., Štefanić S., Steyaert J., et al., "Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.", Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 Aug 01.
Barros-Álvarez, X., Kerchner K. M., Koh C. Yeow, Turley S., Pardon E., Steyaert J., Ranade R. M., J Gillespie R., Zhang Z., Verlinde C. L. M. J., et al., "Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.", Biochimie, vol. 138, pp. 124-136, 2017 Jul.
Vandervelde, A., Drobnak I., Hadži S., Sterckx Y. G. - J., Welte T., De Greve H., Charlier D., Efremov R. G., Loris R., and Lah J., "Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.", Nucleic Acids Res, vol. 45, issue 6, pp. 2937-2950, 2017 Apr 07.
Miller, P. S., Scott S., Masiulis S., De Colibus L., Pardon E., Steyaert J., and A Aricescu R., "Structural basis for GABAA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
2016
Devree, B. T., Mahoney J. P., Vélez-Ruiz G. A., Rasmussen S. G. F., Kuszak A. J., Edwald E., Fung J-J., Manglik A., Masureel M., Du Y., et al., "Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.", Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.
Staus, D. P., Strachan R. T., Manglik A., Pani B., Kahsai A. W., Kim T. Hun, Wingler L. M., Ahn S., Chatterjee A., Masoudi A., et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
Antonik, P. M., Volkov A., Broder U. N., Re D. Lo, van Nuland N. A. J., and Crowley P. B., "Anomer-Specific Recognition and Dynamics in a Fucose-Binding Lectin.", Biochemistry, vol. 55, issue 8, pp. 1195-203, 2016 Mar 01.
Pancsa, R., and Tompa P., "Coding Regions of Intrinsic Disorder Accommodate Parallel Functions.", Trends Biochem Sci, vol. 41, issue 11, pp. 898-906, 2016 Nov.
Fischer, B., Lüthy K., Paesmans J., De Koninck C., Maes I., Swerts J., Kuenen S., Uytterhoeven V., Verstreken P., and Versées W., "Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.", Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
Van Laer, B., Roovers M., Wauters L., Kasprzak J. M., Dyzma M., Deyaert E., Singh R. Kumar, Feller A., Bujnicki J. M., Droogmans L., et al., "Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.", Nucleic Acids Res, vol. 44, issue 2, pp. 940-53, 2016 Jan 29.
Moonens, K., Gideonsson P., Subedi S., Bugaytsova J., Romão E., Mendez M., Nordén J., Fallah M., Rakhimova L., Shevtsova A., et al., "Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.", Cell Host Microbe, vol. 19, issue 1, pp. 55-66, 2016 Jan 13.
Zorzini, V., Mernik A., Lah J., Sterckx Y. G. J., De Jonge N., Garcia-Pino A., De Greve H., Versées W., and Loris R., "Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.", J Biol Chem, vol. 291, issue 21, pp. 10950-60, 2016 May 20.
Lafaye, C., Van Molle I., Dufe V. Tamu, Wahni K., Boudier A., Leroy P., Collet J-F., and Messens J., "Sulfur Denitrosylation by an Engineered Trx-like DsbG Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.", J Biol Chem, vol. 291, issue 29, pp. 15020-8, 2016 07 15.
Guharoy, M., Bhowmick P., Sallam M., and Tompa P., "Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.", Nat Commun, vol. 7, pp. 10239, 2016 Jan 06.
2015
Efremov, R. G., Leitner A., Aebersold R., and Raunser S., "Architecture and conformational switch mechanism of the ryanodine receptor.", Nature, vol. 517, issue 7532, pp. 39-43, 2015 Jan 01.
Tossounian, M-A., Pedre B., Wahni K., Erdogan H., Vertommen D., Van Molle I., and Messens J., "Corynebacterium diphtheriae methionine sulfoxide reductase a exploits a unique mycothiol redox relay mechanism.", J Biol Chem, vol. 290, issue 18, pp. 11365-75, 2015 May 01.
Newman, J. A., Savitsky P., Allerston C. K., Bizard A. H., Özer Ö., Sarlós K., Liu Y., Pardon E., Steyaert J., Hickson I. D., et al., "Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.", Nucleic Acids Res, vol. 43, issue 10, pp. 5221-35, 2015 May 26.
Varadi, M., Guharoy M., Zsolyomi F., and Tompa P., "DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder.", BMC Bioinformatics, vol. 16, pp. 153, 2015 May 13.
Tusnády, G. E., Dobson L., and Tompa P., "Disordered regions in transmembrane proteins.", Biochim Biophys Acta, vol. 1848, issue 11 Pt A, pp. 2839-48, 2015 Nov.
Zorzini, V., Buts L., Schrank E., Sterckx Y. G. J., Respondek M., Engelberg-Kulka H., Loris R., Zangger K., and van Nuland N. A. J., "Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.", Nucleic Acids Res, vol. 43, issue 2, pp. 1241-56, 2015 Jan.
Varadi, M., Zsolyomi F., Guharoy M., and Tompa P., "Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins.", PLoS One, vol. 10, issue 10, pp. e0139731, 2015.
Mackinnon, S. S., and Wodak S. J., "Landscape of intertwined associations in multi-domain homo-oligomeric proteins.", J Mol Biol, vol. 427, issue 2, pp. 350-70, 2015 Jan 30.
Sounier, R., Mas C., Steyaert J., Laeremans T., Manglik A., Huang W., Kobilka B. K., Déméné H., and Granier S., "Propagation of conformational changes during μ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 375-8, 2015 Aug 20.
Aouacheria, A., Combet C., Tompa P., and J Hardwick M., "Redefining the BH3 Death Domain as a 'Short Linear Motif'.", Trends Biochem Sci, vol. 40, issue 12, pp. 736-48, 2015 Dec.

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