Publications
Found 347 results
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"Structural and biochemical analysis of the dual-specificity Trm10 enzyme from prompts reconsideration of its catalytic mechanism.",
RNA, vol. 24, issue 8, pp. 1080-1092, 2018 08.
"Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.",
Nature, vol. 553, issue 7689, pp. 501-505, 2018 01 25.
"The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of .",
J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 08 11.
"Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.",
Biochemistry, vol. 56, issue 30, pp. 3962-3971, 2017 08 01.
"Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.",
Biochimie, vol. 138, pp. 124-136, 2017 Jul.
"Lipid Nanodiscs as a Tool for High-Resolution Structure Determination of Membrane Proteins by Single-Particle Cryo-EM.",
Methods Enzymol, vol. 594, pp. 1-30, 2017.
"The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.",
Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 9, pp. 520-524, 2017 Sep 01.
"Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.",
Nucleic Acids Res, vol. 45, issue 6, pp. 2937-2950, 2017 Apr 07.
"Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.",
Nature, vol. 546, issue 7659, pp. 528-532, 2017 06 22.
"Simultaneous quantification of protein order and disorder.",
Nat Chem Biol, vol. 13, issue 4, pp. 339-342, 2017 03 22.
"Structural basis for GABA receptor potentiation by neurosteroids.",
Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
"Structure of PINK1 in complex with its substrate ubiquitin.",
Nature, vol. 552, issue 7683, pp. 51-56, 2017 12 07.
"Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.",
Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.
"Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.",
Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
"Anomer-Specific Recognition and Dynamics in a Fucose-Binding Lectin.",
Biochemistry, vol. 55, issue 8, pp. 1195-203, 2016 Mar 01.
"Coding Regions of Intrinsic Disorder Accommodate Parallel Functions.",
Trends Biochem Sci, vol. 41, issue 11, pp. 898-906, 2016 Nov.
"Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.",
Proc Natl Acad Sci U S A, vol. 113, issue 44, pp. 12420-12425, 2016 11 01.
"Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.",
Nat Commun, vol. 7, pp. 12101, 2016 07 08.
"Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.",
Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
"Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.",
Nucleic Acids Res, vol. 44, issue 2, pp. 940-53, 2016 Jan 29.
"Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.",
Cell Host Microbe, vol. 19, issue 1, pp. 55-66, 2016 Jan 13.
"Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.",
Proc Natl Acad Sci U S A, vol. 113, issue 30, pp. E4357-66, 2016 07 26.
"Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.",
J Biol Chem, vol. 291, issue 21, pp. 10950-60, 2016 May 20.
"Sulfur Denitrosylation by an Engineered Trx-like DsbG Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.",
J Biol Chem, vol. 291, issue 29, pp. 15020-8, 2016 07 15.
"Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.",
Nat Commun, vol. 7, pp. 10239, 2016 Jan 06.