Publications
Found 28 results
Filters: Keyword is Models, Molecular and Author is Wim Versées [Clear All Filters]
"Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.",
Sci Adv, vol. 4, issue 3, pp. eaap9714, 2018 03.
"Structural and biochemical analysis of the dual-specificity Trm10 enzyme from prompts reconsideration of its catalytic mechanism.",
RNA, vol. 24, issue 8, pp. 1080-1092, 2018 08.
"The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of .",
J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 08 11.
"The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.",
Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 9, pp. 520-524, 2017 Sep 01.
"Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.",
Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
"Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.",
Nucleic Acids Res, vol. 44, issue 2, pp. 940-53, 2016 Jan 29.
"Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.",
Proc Natl Acad Sci U S A, vol. 113, issue 30, pp. E4357-66, 2016 07 26.
"Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.",
J Biol Chem, vol. 291, issue 21, pp. 10950-60, 2016 May 20.
"Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.",
RNA, vol. 20, issue 8, pp. 1257-71, 2014 Aug.
"Structure of an early native-like intermediate of β2-microglobulin amyloidogenesis.",
Protein Sci, vol. 22, issue 10, pp. 1349-57, 2013 Oct.
"Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.",
Nucleic Acids Res, vol. 40, issue 11, pp. 5149-61, 2012 Jun.
"Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.",
Biochim Biophys Acta, vol. 1794, issue 6, pp. 953-60, 2009 Jun.
"G-domain dimerization orchestrates the tRNA wobble modification reaction in the MnmE/GidA complex.",
J Mol Biol, vol. 392, issue 4, pp. 910-22, 2009 Oct 02.
"Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors.",
ChemMedChem, vol. 4, issue 2, pp. 249-60, 2009 Feb.
"Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate.",
J Mol Biol, vol. 380, issue 3, pp. 532-47, 2008 Jul 11.
"A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.",
J Biol Chem, vol. 283, issue 32, pp. 22272-82, 2008 Aug 08.
"N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.",
Bioorg Med Chem, vol. 16, issue 14, pp. 6752-63, 2008 Jul 15.
"Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors.",
Eur J Med Chem, vol. 43, issue 2, pp. 315-26, 2008 Feb.
"The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism.",
FEBS J, vol. 274, issue 9, pp. 2363-75, 2007 May.
"The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes.",
J Mol Biol, vol. 372, issue 5, pp. 1215-26, 2007 Oct 05.
"Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.",
J Biol Chem, vol. 282, issue 48, pp. 35269-78, 2007 Nov 30.
"New insights into the mechanism of nucleoside hydrolases from the crystal structure of the Escherichia coli YbeK protein bound to the reaction product.",
Biochemistry, vol. 45, issue 3, pp. 773-82, 2006 Jan 24.
"Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin.",
FEBS J, vol. 273, issue 11, pp. 2407-20, 2006 Jun.
"Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis.",
J Mol Biol, vol. 359, issue 2, pp. 331-46, 2006 Jun 2.
"Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage.",
J Biol Chem, vol. 280, issue 15, pp. 14799-802, 2005 Apr 15.