Publications
Found 16 results
Filters: Keyword is Variant Surface Glycoproteins, Trypanosoma [Clear All Filters]
"Chronic Trypanosoma congolense infections in mice cause a sustained disruption of the B-cell homeostasis in the bone marrow and spleen.",
Parasite Immunol, vol. 36, issue 5, pp. 187-98, 2014 May.
"High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.",
PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
"T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis.",
PLoS Pathog, vol. 7, issue 6, pp. e1002089, 2011 Jun.
"Current status of vaccination against African trypanosomiasis.",
Parasitology, vol. 137, issue 14, pp. 2017-27, 2010 Dec.
"Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens.",
J Immunol Methods, vol. 329, issue 1-2, pp. 138-50, 2008 Jan 1.
"A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology.",
J Immunol, vol. 179, issue 6, pp. 4003-14, 2007 Sep 15.
"Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes.",
Exp Parasitol, vol. 115, issue 2, pp. 173-80, 2007 Feb.
"Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.",
Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
"The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent.",
J Immunol, vol. 175, issue 4, pp. 2501-9, 2005 Aug 15.
"Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.",
J Biol Chem, vol. 279, issue 2, pp. 1256-61, 2004 Jan 9.
"The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense.",
Am J Trop Med Hyg, vol. 67, issue 6, pp. 684-90, 2002 Dec.
"VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology.",
Microbes Infect, vol. 4, issue 9, pp. 999-1006, 2002 Jul.
"A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.",
J Biol Chem, vol. 276, issue 36, pp. 33458-64, 2001 Sep 7.
"Antibodies raised against the flagellar pocket fraction of Trypanosoma brucei preferentially recognize HSP60 in cDNA expression library.",
Parasite Immunol, vol. 22, issue 12, pp. 639-50, 2000 Dec.
"Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei.",
Infect Immun, vol. 68, issue 2, pp. 848-60, 2000 Feb.
"The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors.",
J Immunol, vol. 160, issue 4, pp. 1949-56, 1998 Feb 15.