Publications
Found 49 results
Filters: Keyword is Mutagenesis, Site-Directed [Clear All Filters]
"Sulfur Denitrosylation by an Engineered Trx-like DsbG Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.",
J Biol Chem, vol. 291, issue 29, pp. 15020-8, 2016 07 15.
"A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.",
Pathog Dis, vol. 71, issue 1, pp. 39-54, 2014 Jun.
"Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host.",
Science, vol. 337, issue 6093, pp. 463-6, 2012 Jul 27.
"Alternative interactions define gyrase specificity in the CcdB family.",
Mol Microbiol, vol. 84, issue 5, pp. 965-78, 2012 Jun.
"A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes.",
Nat Biotechnol, vol. 30, issue 12, pp. 1225-31, 2012 Dec.
"Efflux permease CgAcr3-1 of Corynebacterium glutamicum is an arsenite-specific antiporter.",
J Biol Chem, vol. 287, issue 1, pp. 723-35, 2012 Jan 02.
"Mutational and structural analysis of L-N-carbamoylase reveals new insights into a peptidase M20/M25/M40 family member.",
J Bacteriol, vol. 194, issue 21, pp. 5759-68, 2012 Nov.
"Empirical estimation of the energetic contribution of individual interface residues in structures of protein-protein complexes.",
J Comput Aided Mol Des, vol. 23, issue 9, pp. 645-54, 2009 Sep.
"General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.",
J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
"The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin.",
J Mol Biol, vol. 368, issue 3, pp. 800-11, 2007 May 4.
"Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin.",
Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 62, issue Pt 12, pp. 1255-8, 2006 Dec 1.
"Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family.",
J Mol Biol, vol. 360, issue 4, pp. 826-38, 2006 Jul 21.
"Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.",
J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
"Molecular basis of gyrase poisoning by the addiction toxin CcdB.",
J Mol Biol, vol. 348, issue 5, pp. 1091-102, 2005 May 20.
"Multiple interactions of the 'transducer' govern its function in calpain activation by Ca2+.",
Biochem J, vol. 388, issue Pt 3, pp. 741-4, 2005 Jun 15.
"Contribution of distinct structural elements to activation of calpain by Ca2+ ions.",
J Biol Chem, vol. 279, issue 19, pp. 20118-26, 2004 May 7.
"How thioredoxin can reduce a buried disulphide bond.",
J Mol Biol, vol. 339, issue 3, pp. 527-37, 2004 Jun 4.
"Leaving group activation by aromatic stacking: an alternative to general acid catalysis.",
J Mol Biol, vol. 338, issue 1, pp. 1-6, 2004 Apr 16.
"On the sequential determinants of calpain cleavage.",
J Biol Chem, vol. 279, issue 20, pp. 20775-85, 2004 May 14.
"The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.",
Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 6, pp. 1180-4, 2004 Jun.
"Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: evidence for local rearrangements during folding from high concentrations of denaturant.",
Biochemistry, vol. 42, issue 17, pp. 4883-95, 2003 May 6.
"Lack of negative charge in the E46Q mutant of photoactive yellow protein prevents partial unfolding of the blue-shifted intermediate.",
Biochemistry, vol. 42, issue 49, pp. 14501-6, 2003 Dec 16.
"Rapid formation of non-native contacts during the folding of HPr revealed by real-time photo-CIDNP NMR and stopped-flow fluorescence experiments.",
J Mol Biol, vol. 330, issue 2, pp. 397-407, 2003 Jul 4.
"Specific potassium binding stabilizes pI258 arsenate reductase from Staphylococcus aureus.",
J Biol Chem, vol. 278, issue 27, pp. 24673-9, 2003 Jul 4.
"All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.",
Proc Natl Acad Sci U S A, vol. 99, issue 13, pp. 8506-11, 2002 Jun 25.