Publications

Found 16 results
Filters: Keyword is Mutagenesis, Site-Directed and Author is Remy Loris  [Clear All Filters]
2012
De Jonge, N., M. Simic, L. Buts, S. Haesaerts, K. Roelants, A. Garcia-Pino, Y. Sterckx, H. De Greve, J. Lah, and R. Loris, "Alternative interactions define gyrase specificity in the CcdB family.", Mol Microbiol, vol. 84, issue 5, pp. 965-78, 2012 Jun.
Martinez-Rodriguez, S., A. Garcia-Pino, F. Javier Las Heras-Vázquez, J. María Clemente-Jiménez, F. Rodríguez-Vico, J. M. García-Ruiz, R. Loris, and J. Antonio Gavira, "Mutational and structural analysis of L-N-carbamoylase reveals new insights into a peptidase M20/M25/M40 family member.", J Bacteriol, vol. 194, issue 21, pp. 5759-68, 2012 Nov.
2009
Vincke, C., R. Loris, D. Saerens, S. Martinez-Rodriguez, S. Muyldermans, and K. Conrath, "General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.", J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
2007
Roos, G., A. Garcia-Pino, K. Van Belle, E. Brosens, K. Wahni, G. Vandenbussche, L. Wyns, R. Loris, and J. Messens, "The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin.", J Mol Biol, vol. 368, issue 3, pp. 800-11, 2007 May 4.
2006
Roos, G., E. Brosens, K. Wahni, A. Desmyter, S. Spinelli, L. Wyns, J. Messens, and R. Loris, "Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 62, issue Pt 12, pp. 1255-8, 2006 Dec 1.
Roos, G., L. Buts, K. Van Belle, E. Brosens, P. Geerlings, R. Loris, L. Wyns, and J. Messens, "Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family.", J Mol Biol, vol. 360, issue 4, pp. 826-38, 2006 Jul 21.
2005
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
Dao-Thi, M-H., L. Van Melderen, E. De Genst, H. Afif, L. Buts, L. Wyns, and R. Loris, "Molecular basis of gyrase poisoning by the addiction toxin CcdB.", J Mol Biol, vol. 348, issue 5, pp. 1091-102, 2005 May 20.
2004
Messens, J., I. Van Molle, P. Vanhaesebrouck, M. Limbourg, K. Van Belle, K. Wahni, J. C. Martins, R. Loris, and L. Wyns, "How thioredoxin can reduce a buried disulphide bond.", J Mol Biol, vol. 339, issue 3, pp. 527-37, 2004 Jun 4.
Messens, J., I. Van Molle, P. Vanhaesebrouck, K. Van Belle, K. Wahni, J. C. Martins, L. Wyns, and R. Loris, "The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.", Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 6, pp. 1180-4, 2004 Jun.
2001
De Vos, S., J. Backmann, M. Prévost, J. Steyaert, and R. Loris, "Hydrophobic core manipulations in ribonuclease T1.", Biochemistry, vol. 40, issue 34, pp. 10140-9, 2001 Aug 28.
1999
Hamelryck, T. W., R. Loris, J. Bouckaert, M-H. Dao-Thi, G. Strecker, A. Imberty, E. Fernandez, L. Wyns, and M. Etzler, "Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.", J Mol Biol, vol. 286, issue 4, pp. 1161-77, 1999 Mar 5.
Langhorst, U., R. Loris, V. P. Denisov, J. Doumen, P. Roose, D. Maes, B. Halle, and J. Steyaert, "Dissection of the structural and functional role of a conserved hydration site in RNase T1.", Protein Sci, vol. 8, issue 4, pp. 722-30, 1999 Apr.
1998
Dao-Thi, M-H., L. Wyns, F. Poortmans, E. M. Bahassi, M. Couturier, and R. Loris, "Crystallization of ccdB.", Acta Crystallogr D Biol Crystallogr, vol. 54, issue Pt 5, pp. 975-81, 1998 Sep 1.
Loris, R., T. W. Hamelryck, J. Bouckaert, and L. Wyns, "Legume lectin structure.", Biochim Biophys Acta, vol. 1383, issue 1, pp. 9-36, 1998 Mar 3.
1996
Doumen, J., M. Gonciarz, I. Zegers, R. Loris, L. Wyns, and J. Steyaert, "A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.", Protein Sci, vol. 5, issue 8, pp. 1523-30, 1996 Aug.