Publications

Found 36 results
Filters: Keyword is Bacterial Toxins  [Clear All Filters]
2019
Talavera, A., H. Tamman, A. Ainelo, A. Konijnenberg, S. Hadži, F. Sobott, A. Garcia-Pino, R. Hõrak, and R. Loris, "A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.", Nat Commun, vol. 10, issue 1, pp. 972, 2019 02 27.
2017
Efremov, R. G., C. Gatsogiannis, and S. Raunser, "Lipid Nanodiscs as a Tool for High-Resolution Structure Determination of Membrane Proteins by Single-Particle Cryo-EM.", Methods Enzymol, vol. 594, pp. 1-30, 2017.
Vandervelde, A., I. Drobnak, S. Hadži, Y. G. - J. Sterckx, T. Welte, H. De Greve, D. Charlier, R. G. Efremov, R. Loris, and J. Lah, "Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.", Nucleic Acids Res, vol. 45, issue 6, pp. 2937-2950, 2017 Apr 07.
Talavera, A., H. Tamman, A. Ainelo, S. Hadǽi, A. Garcia-Pino, R. Hõrak, A. Konijnenberg, and R. Loris, "Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 8, pp. 455-462, 2017 Aug 01.
Hadži, S., A. Garcia-Pino, S. Haesaerts, D. Jurenas, K. Gerdes, J. Lah, and R. Loris, "Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.", Nucleic Acids Res, vol. 45, issue 8, pp. 4972-4983, 2017 May 05.
2016
Sterckx, Y. G. - J., T. Jové, A. V. Shkumatov, A. Garcia-Pino, L. Geerts, M. De Kerpel, J. Lah, H. De Greve, L. Van Melderen, and R. Loris, "A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.", J Mol Biol, vol. 428, issue 8, pp. 1589-603, 2016 Apr 24.
2015
Hadži, S., A. Garcia-Pino, K. Gerdes, J. Lah, and R. Loris, "Crystallization of two operator complexes from the Vibrio cholerae HigBA2 toxin-antitoxin module.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 2, pp. 226-33, 2015 Feb.
Verstraeten, N., W. Joris Knapen, C. Ines Kint, V. Liebens, B. Van den Bergh, L. Dewachter, J. Elie Michiels, Q. Fu, C. Claudia David, A. Carolina Fierro, et al., "Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.", Mol Cell, vol. 59, issue 1, pp. 9-21, 2015 Jul 02.
2014
Sterckx, Y. G. J., S. Haesaerts, L. Van Melderen, and R. Loris, "Crystallization and preliminary X-ray analysis of two variants of the Escherichia coli O157 ParE2-PaaA2 toxin-antitoxin complex.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 9, pp. 1284-91, 2014 Sep.
Meusch, D., C. Gatsogiannis, R. G. Efremov, A. E. Lang, O. Hofnagel, I. R. Vetter, K. Aktories, and S. Raunser, "Mechanism of Tc toxin action revealed in molecular detail.", Nature, vol. 508, issue 7494, pp. 61-5, 2014 Apr 03.
Sterckx, Y. G. J., A. Volkov, W. F. Vranken, J. Kragelj, M. Ringkjøbi Jensen, L. Buts, A. Garcia-Pino, T. Jové, L. Van Melderen, M. Blackledge, et al., "Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2.", Structure, vol. 22, issue 6, pp. 854-65, 2014 Jun 10.
Zorzini, V., L. Buts, M. Sleutel, A. Garcia-Pino, A. Talavera, S. Haesaerts, H. De Greve, A. Cheung, N. A. J. van Nuland, and R. Loris, "Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics.", Nucleic Acids Res, vol. 42, issue 10, pp. 6709-25, 2014 Jun.
2013
Behdani, M., S. Zeinali, M. Karimipour, H. Khanahmad, S. Schoonooghe, A. Aslemarz, N. Seyed, R. Moazami-Godarzi, F. Baniahmad, M. Habibi-Anbouhi, et al., "Development of VEGFR2-specific Nanobody Pseudomonas exotoxin A conjugated to provide efficient inhibition of tumor cell growth.", N Biotechnol, vol. 30, issue 2, pp. 205-9, 2013 Jan 25.
Gelens, L., L. Hill, A. Vandervelde, J. Danckaert, and R. Loris, "A general model for toxin-antitoxin module dynamics can explain persister cell formation in E. coli.", PLoS Comput Biol, vol. 9, issue 8, pp. e1003190, 2013.
Ghequire, M. G. K., A. Garcia-Pino, E. K. M. Lebbe, S. Spaepen, R. Loris, and R. De Mot, "Structural determinants for activity and specificity of the bacterial toxin LlpA.", PLoS Pathog, vol. 9, issue 2, pp. e1003199, 2013 Feb.
2012
Sterckx, Y., A. Garcia-Pino, S. Haesaerts, T. Jové, L. Geerts, V. Sakellaris, L. Van Melderen, and R. Loris, "The ParE2-PaaA2 toxin-antitoxin complex from Escherichia coli O157 forms a heterodocecamer in solution and in the crystal.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 68, issue Pt 6, pp. 724-9, 2012 Jun 1.
2011
Zorzini, V., S. Haesaerts, A. Cheung, R. Loris, and N. A. J. van Nuland, "1H, 13C, and 15N backbone and side-chain chemical shift assignment of the staphylococcal MazF mRNA interferase.", Biomol NMR Assign, vol. 5, issue 2, pp. 157-60, 2011 Oct.
2010
Hallez, R., D. Geeraerts, Y. Sterckx, N. Mine, R. Loris, and L. Van Melderen, "New toxins homologous to ParE belonging to three-component toxin-antitoxin systems in Escherichia coli O157:H7.", Mol Microbiol, vol. 76, issue 3, pp. 719-32, 2010 May.
Göbl, C., S. Kosol, T. Stockner, H. M. Rückert, and K. Zangger, "Solution structure and membrane binding of the toxin fst of the par addiction module.", Biochemistry, vol. 49, issue 31, pp. 6567-75, 2010 Aug 10.
De Jonge, N., W. Hohlweg, A. Garcia-Pino, M. Respondek, L. Buts, S. Haesaerts, J. Lah, K. Zangger, and R. Loris, "Structural and thermodynamic characterization of Vibrio fischeri CcdB.", J Biol Chem, vol. 285, issue 8, pp. 5606-13, 2010 Feb 19.
2009
Simic, M., N. De Jonge, R. Loris, G. Vesnaver, and J. Lah, "Driving forces of gyrase recognition by the addiction toxin CcdB.", J Biol Chem, vol. 284, issue 30, pp. 20002-10, 2009 Jul 24.
De Jonge, N., A. Garcia-Pino, L. Buts, S. Haesaerts, D. Charlier, K. Zangger, L. Wyns, H. De Greve, and R. Loris, "Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain.", Mol Cell, vol. 35, issue 2, pp. 154-63, 2009 Jul 31.
Respondek, M., L. Buts, N. De Jonge, S. Haesaerts, R. Loris, L. Van Melderen, L. Wyns, and K. Zangger, "Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri.", Biomol NMR Assign, vol. 3, issue 1, pp. 145-7, 2009 Jun.
2008
Garcia-Pino, A., M. Christensen-Dalsgaard, L. Wyns, M. Yarmolinsky, R. David Magnuson, K. Gerdes, and R. Loris, "Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation.", J Biol Chem, vol. 283, issue 45, pp. 30821-7, 2008 Nov 7.
2005
Buts, L., N. De Jonge, R. Loris, L. Wyns, and M-H. Dao-Thi, "Crystallization of the C-terminal domain of the addiction antidote CcdA in complex with its toxin CcdB.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 61, issue Pt 10, pp. 949-52, 2005 Oct 1.

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