Publications

Found 27 results
Filters: Keyword is Bacterial Toxins and Author is Remy Loris  [Clear All Filters]
2017
Vandervelde, A., I. Drobnak, S. Hadži, Y. G. - J. Sterckx, T. Welte, H. De Greve, D. Charlier, R. G. Efremov, R. Loris, and J. Lah, "Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.", Nucleic Acids Res, vol. 45, issue 6, pp. 2937-2950, 2017 Apr 07.
Talavera, A., H. Tamman, A. Ainelo, S. Hadǽi, A. Garcia-Pino, R. Hõrak, A. Konijnenberg, and R. Loris, "Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 8, pp. 455-462, 2017 Aug 01.
Hadži, S., A. Garcia-Pino, S. Haesaerts, D. Jurenas, K. Gerdes, J. Lah, and R. Loris, "Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.", Nucleic Acids Res, vol. 45, issue 8, pp. 4972-4983, 2017 May 05.
2016
Sterckx, Y. G. - J., T. Jové, A. V. Shkumatov, A. Garcia-Pino, L. Geerts, M. De Kerpel, J. Lah, H. De Greve, L. Van Melderen, and R. Loris, "A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.", J Mol Biol, vol. 428, issue 8, pp. 1589-603, 2016 Apr 24.
2015
Hadži, S., A. Garcia-Pino, K. Gerdes, J. Lah, and R. Loris, "Crystallization of two operator complexes from the Vibrio cholerae HigBA2 toxin-antitoxin module.", Acta Crystallogr F Struct Biol Commun, vol. 71, issue Pt 2, pp. 226-33, 2015 Feb.
2014
Sterckx, Y. G. J., S. Haesaerts, L. Van Melderen, and R. Loris, "Crystallization and preliminary X-ray analysis of two variants of the Escherichia coli O157 ParE2-PaaA2 toxin-antitoxin complex.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 9, pp. 1284-91, 2014 Sep.
Sterckx, Y. G. J., A. Volkov, W. F. Vranken, J. Kragelj, M. Ringkjøbi Jensen, L. Buts, A. Garcia-Pino, T. Jové, L. Van Melderen, M. Blackledge, et al., "Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2.", Structure, vol. 22, issue 6, pp. 854-65, 2014 Jun 10.
Zorzini, V., L. Buts, M. Sleutel, A. Garcia-Pino, A. Talavera, S. Haesaerts, H. De Greve, A. Cheung, N. A. J. van Nuland, and R. Loris, "Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics.", Nucleic Acids Res, vol. 42, issue 10, pp. 6709-25, 2014 Jun.
2013
Gelens, L., L. Hill, A. Vandervelde, J. Danckaert, and R. Loris, "A general model for toxin-antitoxin module dynamics can explain persister cell formation in E. coli.", PLoS Comput Biol, vol. 9, issue 8, pp. e1003190, 2013.
Ghequire, M. G. K., A. Garcia-Pino, E. K. M. Lebbe, S. Spaepen, R. Loris, and R. De Mot, "Structural determinants for activity and specificity of the bacterial toxin LlpA.", PLoS Pathog, vol. 9, issue 2, pp. e1003199, 2013 Feb.
2012
Sterckx, Y., A. Garcia-Pino, S. Haesaerts, T. Jové, L. Geerts, V. Sakellaris, L. Van Melderen, and R. Loris, "The ParE2-PaaA2 toxin-antitoxin complex from Escherichia coli O157 forms a heterodocecamer in solution and in the crystal.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 68, issue Pt 6, pp. 724-9, 2012 Jun 1.
2011
Zorzini, V., S. Haesaerts, A. Cheung, R. Loris, and N. A. J. van Nuland, "1H, 13C, and 15N backbone and side-chain chemical shift assignment of the staphylococcal MazF mRNA interferase.", Biomol NMR Assign, vol. 5, issue 2, pp. 157-60, 2011 Oct.
2010
Hallez, R., D. Geeraerts, Y. Sterckx, N. Mine, R. Loris, and L. Van Melderen, "New toxins homologous to ParE belonging to three-component toxin-antitoxin systems in Escherichia coli O157:H7.", Mol Microbiol, vol. 76, issue 3, pp. 719-32, 2010 May.
De Jonge, N., W. Hohlweg, A. Garcia-Pino, M. Respondek, L. Buts, S. Haesaerts, J. Lah, K. Zangger, and R. Loris, "Structural and thermodynamic characterization of Vibrio fischeri CcdB.", J Biol Chem, vol. 285, issue 8, pp. 5606-13, 2010 Feb 19.
2009
Simic, M., N. De Jonge, R. Loris, G. Vesnaver, and J. Lah, "Driving forces of gyrase recognition by the addiction toxin CcdB.", J Biol Chem, vol. 284, issue 30, pp. 20002-10, 2009 Jul 24.
De Jonge, N., A. Garcia-Pino, L. Buts, S. Haesaerts, D. Charlier, K. Zangger, L. Wyns, H. De Greve, and R. Loris, "Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain.", Mol Cell, vol. 35, issue 2, pp. 154-63, 2009 Jul 31.
Respondek, M., L. Buts, N. De Jonge, S. Haesaerts, R. Loris, L. Van Melderen, L. Wyns, and K. Zangger, "Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri.", Biomol NMR Assign, vol. 3, issue 1, pp. 145-7, 2009 Jun.
2008
Garcia-Pino, A., M. Christensen-Dalsgaard, L. Wyns, M. Yarmolinsky, R. David Magnuson, K. Gerdes, and R. Loris, "Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation.", J Biol Chem, vol. 283, issue 45, pp. 30821-7, 2008 Nov 7.
2005
Buts, L., N. De Jonge, R. Loris, L. Wyns, and M-H. Dao-Thi, "Crystallization of the C-terminal domain of the addiction antidote CcdA in complex with its toxin CcdB.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 61, issue Pt 10, pp. 949-52, 2005 Oct 1.
Dao-Thi, M-H., L. Van Melderen, E. De Genst, H. Afif, L. Buts, L. Wyns, and R. Loris, "Molecular basis of gyrase poisoning by the addiction toxin CcdB.", J Mol Biol, vol. 348, issue 5, pp. 1091-102, 2005 May 20.
Buts, L., J. Lah, M-H. Dao-Thi, L. Wyns, and R. Loris, "Toxin-antitoxin modules as bacterial metabolic stress managers.", Trends Biochem Sci, vol. 30, issue 12, pp. 672-9, 2005 Dec.
2004
Dao-Thi, M-H., L. Van Melderen, E. De Genst, L. Buts, A. Ranquin, L. Wyns, and R. Loris, "Crystallization of CcdB in complex with a GyrA fragment.", Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 6, pp. 1132-4, 2004 Jun.
Buts, L., M-H. Dao-Thi, L. Wyns, and R. Loris, "Untangle, a tool for filtering overlapping diffraction patterns from multicrystals.", Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 5, pp. 983-4, 2004 May.
2002
Dao-Thi, M-H., D. Charlier, R. Loris, D. Maes, J. Messens, L. Wyns, and J. Backmann, "Intricate interactions within the ccd plasmid addiction system.", J Biol Chem, vol. 277, issue 5, pp. 3733-42, 2002 Feb 1.
1999
Loris, R., M-H. Dao-Thi, E. M. Bahassi, L. Van Melderen, F. Poortmans, R. Liddington, M. Couturier, and L. Wyns, "Crystal structure of CcdB, a topoisomerase poison from E. coli.", J Mol Biol, vol. 285, issue 4, pp. 1667-77, 1999 Jan 29.

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