Publications
Found 163 results
Filters: Keyword is Binding Sites [Clear All Filters]
"Intrinsically Disordered Linkers Impart Processivity on Enzymes by Spatial Confinement of Binding Domains.",
Int J Mol Sci, vol. 20, issue 9, 2019 Apr 29.
"Structural and biochemical analysis of the dual-specificity Trm10 enzyme from prompts reconsideration of its catalytic mechanism.",
RNA, vol. 24, issue 8, pp. 1080-1092, 2018 08.
"Structural Basis of Epitope Recognition by Heavy-Chain Camelid Antibodies.",
J Mol Biol, vol. 430, issue 21, pp. 4369-4386, 2018 10 19.
"Structural snapshots of OxyR reveal the peroxidatic mechanism of HO sensing.",
Proc Natl Acad Sci U S A, vol. 115, issue 50, pp. E11623-E11632, 2018 12 11.
"Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.",
Nature, vol. 553, issue 7689, pp. 501-505, 2018 01 25.
"Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.",
Biochimie, vol. 138, pp. 124-136, 2017 Jul.
"Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.",
Sci Rep, vol. 7, issue 1, pp. 4676, 2017 07 05.
"Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.",
Nucleic Acids Res, vol. 45, issue 6, pp. 2937-2950, 2017 Apr 07.
"Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.",
Biochem Biophys Res Commun, vol. 487, issue 2, pp. 403-408, 2017 05 27.
"Structure of PINK1 in complex with its substrate ubiquitin.",
Nature, vol. 552, issue 7683, pp. 51-56, 2017 12 07.
"Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.",
Proc Natl Acad Sci U S A, vol. 113, issue 44, pp. 12420-12425, 2016 11 01.
"Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.",
Nat Commun, vol. 7, pp. 12101, 2016 07 08.
"Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.",
Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
"Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.",
Cell Host Microbe, vol. 19, issue 1, pp. 55-66, 2016 Jan 13.
"Sulfur Denitrosylation by an Engineered Trx-like DsbG Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.",
J Biol Chem, vol. 291, issue 29, pp. 15020-8, 2016 07 15.
"Propagation of conformational changes during μ-opioid receptor activation.",
Nature, vol. 524, issue 7565, pp. 375-8, 2015 Aug 20.
"Structural and functional insight into the carbohydrate receptor binding of F4 fimbriae-producing enterotoxigenic Escherichia coli.",
J Biol Chem, vol. 290, issue 13, pp. 8409-19, 2015 Mar 27.
"Structural insights into µ-opioid receptor activation.",
Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.
"The concerted action of a positive charge and hydrogen bonds dynamically regulates the pKa of the nucleophilic cysteine in the NrdH-redoxin family.",
Protein Sci, vol. 23, issue 2, pp. 238-42, 2014 Feb.
"Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.",
Nat Struct Mol Biol, vol. 21, issue 11, pp. 990-6, 2014 Nov.
"Mechanism of Tc toxin action revealed in molecular detail.",
Nature, vol. 508, issue 7494, pp. 61-5, 2014 Apr 03.
"A million peptide motifs for the molecular biologist.",
Mol Cell, vol. 55, issue 2, pp. 161-9, 2014 Jul 17.
"The molecular mechanism of Shiga toxin Stx2e neutralization by a single-domain antibody targeting the cell receptor-binding domain.",
J Biol Chem, vol. 289, issue 36, pp. 25374-81, 2014 Sep 05.
"Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics.",
Nucleic Acids Res, vol. 42, issue 10, pp. 6709-25, 2014 Jun.
"Activation and allosteric modulation of a muscarinic acetylcholine receptor.",
Nature, vol. 504, issue 7478, pp. 101-6, 2013 Dec 05.