Publications

Found 255 results
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2019
Szabo, B., T. Horvath, E. Schad, N. Murvai, Á. Tantos, L. Kalmar, L. Beatriz Chemes, K-H. Han, and P. Tompa, "Intrinsically Disordered Linkers Impart Processivity on Enzymes by Spatial Confinement of Binding Domains.", Int J Mol Sci, vol. 20, issue 9, 2019 Apr 29.
2018
Bekesi, A., S. Abdellaoui, N. Holroyd, W. Van Delm, E. Pardon, J. Pauwels, K. Gevaert, J. Steyaert, S. Derveaux, A. Borysik, et al., "Challenges in the Structural-Functional Characterization of Multidomain, Partially Disordered Proteins CBP and p300: Preparing Native Proteins and Developing Nanobody Tools.", Methods Enzymol, vol. 611, pp. 607-675, 2018.
2017
Barros-Álvarez, X., K. M. Kerchner, C. Yeow Koh, S. Turley, E. Pardon, J. Steyaert, R. M. Ranade, R. J Gillespie, Z. Zhang, C. L. M. J. Verlinde, et al., "Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.", Biochimie, vol. 138, pp. 124-136, 2017 Jul.
Deyaert, E., A. Kortholt, and W. Versées, "The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 9, pp. 520-524, 2017 Sep 01.
Talavera, A., H. Tamman, A. Ainelo, S. Hadǽi, A. Garcia-Pino, R. Hõrak, A. Konijnenberg, and R. Loris, "Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 8, pp. 455-462, 2017 Aug 01.
Spaulding, C. N., R. D. Klein, S. Ruer, A. L. Kau, H. L. Schreiber, Z. T. Cusumano, K. W. Dodson, J. S. Pinkner, D. H. Fremont, J. W. Janetka, et al., "Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.", Nature, vol. 546, issue 7659, pp. 528-532, 2017 06 22.
Hadži, S., A. Mernik, Č. Podlipnik, R. Loris, and J. Lah, "The Thermodynamic Basis of the Fuzzy Interaction of an Intrinsically Disordered Protein.", Angew Chem Int Ed Engl, vol. 56, issue 46, pp. 14494-14497, 2017 11 13.
2016
Antonik, P. M., A. N. Volkov, U. N. Broder, D. Lo Re, N. A. J. van Nuland, and P. B. Crowley, "Anomer-Specific Recognition and Dynamics in a Fucose-Binding Lectin.", Biochemistry, vol. 55, issue 8, pp. 1195-203, 2016 Mar 01.
Hubin, E., F. Cioffi, J. Rozenski, N. A. J. van Nuland, and K. Broersen, "Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states.", Biochim Biophys Acta, vol. 1860, issue 6, pp. 1281-90, 2016 Jun.
Wijckmans, E., M. Nys, S. Debaveye, M. Brams, E. Pardon, K. Willegems, D. Bertrand, J. Steyaert, R. G. Efremov, and C. Ulens, "Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.", PLoS One, vol. 11, issue 3, pp. e0151183, 2016.
Piai, A., E. O. Calçada, T. Tarenzi, A. Del Grande, M. Varadi, P. Tompa, I. C. Felli, and R. Pierattelli, "Just a Flexible Linker? The Structural and Dynamic Properties of CBP-ID4 Revealed by NMR Spectroscopy.", Biophys J, vol. 110, issue 2, pp. 372-81, 2016 Jan 19.
Guaitoli, G., F. Raimondi, B. K. Gilsbach, Y. Gómez-Llorente, E. Deyaert, F. Renzi, X. Li, A. Schaffner, P. Kumar Anku Jagtap, K. Boldt, et al., "Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.", Proc Natl Acad Sci U S A, vol. 113, issue 30, pp. E4357-66, 2016 07 26.
Sterckx, Y. G. - J., T. Jové, A. V. Shkumatov, A. Garcia-Pino, L. Geerts, M. De Kerpel, J. Lah, H. De Greve, L. Van Melderen, and R. Loris, "A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.", J Mol Biol, vol. 428, issue 8, pp. 1589-603, 2016 Apr 24.
2015
Bhowmick, P., M. Guharoy, and P. Tompa, "Bioinformatics Approaches for Predicting Disordered Protein Motifs.", Adv Exp Med Biol, vol. 870, pp. 291-318, 2015.
Tossounian, M-A., B. Pedre, K. Wahni, H. Erdogan, D. Vertommen, I. Van Molle, and J. Messens, "Corynebacterium diphtheriae methionine sulfoxide reductase a exploits a unique mycothiol redox relay mechanism.", J Biol Chem, vol. 290, issue 18, pp. 11365-75, 2015 May 01.
Varadi, M., M. Guharoy, F. Zsolyomi, and P. Tompa, "DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder.", BMC Bioinformatics, vol. 16, pp. 153, 2015 May 13.
Tusnády, G. E., L. Dobson, and P. Tompa, "Disordered regions in transmembrane proteins.", Biochim Biophys Acta, vol. 1848, issue 11 Pt A, pp. 2839-48, 2015 Nov.
Varadi, M., F. Zsolyomi, M. Guharoy, and P. Tompa, "Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins.", PLoS One, vol. 10, issue 10, pp. e0139731, 2015.
Tompa, P., E. Schad, Á. Tantos, and L. Kalmar, "Intrinsically disordered proteins: emerging interaction specialists.", Curr Opin Struct Biol, vol. 35, pp. 49-59, 2015 Dec.
Coppens, F., J. Iyyathurai, S. Ruer, A. Fioravanti, J. Taganna, L. Vereecke, H. De Greve, and H. Remaut, "Structural and adhesive properties of the long polar fimbriae protein LpfD from adherent-invasive Escherichia coli.", Acta Crystallogr D Biol Crystallogr, vol. 71, issue Pt 8, pp. 1615-26, 2015 Aug.
Moonens, K., I. Van den Broeck, M. De Kerpel, F. Deboeck, H. Raymaekers, H. Remaut, and H. De Greve, "Structural and functional insight into the carbohydrate receptor binding of F4 fimbriae-producing enterotoxigenic Escherichia coli.", J Biol Chem, vol. 290, issue 13, pp. 8409-19, 2015 Mar 27.
2014
Van Laer, K., M. Oliveira, K. Wahni, and J. Messens, "The concerted action of a positive charge and hydrogen bonds dynamically regulates the pKa of the nucleophilic cysteine in the NrdH-redoxin family.", Protein Sci, vol. 23, issue 2, pp. 238-42, 2014 Feb.
Lee, C., L. Kalmar, B. Xue, P. Tompa, G. W. Daughdrill, V. N. Uversky, and K-H. Han, "Contribution of proline to the pre-structuring tendency of transient helical secondary structure elements in intrinsically disordered proteins.", Biochim Biophys Acta, vol. 1840, issue 3, pp. 993-1003, 2014 Mar.
Ehrnstorfer, I. A., E. R. Geertsma, E. Pardon, J. Steyaert, and R. Dutzler, "Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.", Nat Struct Mol Biol, vol. 21, issue 11, pp. 990-6, 2014 Nov.
Sterckx, Y. G. J., S. Haesaerts, L. Van Melderen, and R. Loris, "Crystallization and preliminary X-ray analysis of two variants of the Escherichia coli O157 ParE2-PaaA2 toxin-antitoxin complex.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 9, pp. 1284-91, 2014 Sep.

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