Publications

Found 10 results
Filters: Keyword is Amino Acid Sequence and Author is Dirk Saerens  [Clear All Filters]
2011
Ben Abderrazek, R., C. Vincke, I. Hmila, D. Saerens, N. Abidi, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin.", Protein Eng Des Sel, vol. 24, issue 9, pp. 727-35, 2011 Sep.
Stijlemans, B., G. Caljon, S. Kumar A. Natesan, D. Saerens, K. Conrath, D. Pérez-Morga, J. N. Skepper, A. Nikolaou, L. Brys, E. Pays, et al., "High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.", PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
2009
Vincke, C., R. Loris, D. Saerens, S. Martinez-Rodriguez, S. Muyldermans, and K. Conrath, "General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.", J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
Ben Abderrazek, R., I. Hmila, C. Vincke, Z. Benlasfar, M. Pellis, H. Dabbek, D. Saerens, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "Identification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom.", Biochem J, vol. 424, issue 2, pp. 263-72, 2009 Dec 1.
Deckers, N., D. Saerens, K. Kanobana, K. Conrath, B. Victor, U. Wernery, J. Vercruysse, S. Muyldermans, and P. Dorny, "Nanobodies, a promising tool for species-specific diagnosis of Taenia solium cysticercosis.", Int J Parasitol, vol. 39, issue 5, pp. 625-33, 2009 Apr.
2008
Saerens, D., K. Conrath, J. Govaert, and S. Muyldermans, "Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.", J Mol Biol, vol. 377, issue 2, pp. 478-88, 2008 Mar 21.
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
Saerens, D., B. Stijlemans, T. Nath Baral, G. Thanh Nguy Thi, U. Wernery, S. Magez, P. De Baetselier, S. Muyldermans, and K. Conrath, "Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens.", J Immunol Methods, vol. 329, issue 1-2, pp. 138-50, 2008 Jan 1.
2005
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
2004
Saerens, D., J. Kinne, E. Bosmans, U. Wernery, S. Muyldermans, and K. Conrath, "Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.", J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.