Publications

Found 313 results
Filters: Keyword is Protein Conformation  [Clear All Filters]
2017
Rosado, L. Astolfi, Wahni K., Degiacomi G., Pedre B., Young D., de la Rubia A. G., Boldrin F., Martens E., Marcos-Pascual L., Sancho-Vaello E., et al., "The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of .", J Biol Chem, vol. 292, issue 32, pp. 13097-13110, 2017 08 11.
Deyaert, E., Kortholt A., and Versées W., "The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 9, pp. 520-524, 2017 Sep 01.
Manglik, A., Kobilka B. K., and Steyaert J., "Nanobodies to Study G Protein-Coupled Receptor Structure and Function.", Annu Rev Pharmacol Toxicol, vol. 57, pp. 19-37, 2017 01 06.
Sormanni, P., Piovesan D., Heller G. T., Bonomi M., Kukic P., Camilloni C., Fuxreiter M., Dosztányi Z., Pappu R. V., M Babu M., et al., "Simultaneous quantification of protein order and disorder.", Nat Chem Biol, vol. 13, issue 4, pp. 339-342, 2017 03 22.
Wohlkonig, A., Remaut H., Moune M., Tanina A., Meyer F., Desroses M., Steyaert J., Willand N., Baulard A. R., and Wintjens R., "Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.", Biochem Biophys Res Commun, vol. 487, issue 2, pp. 403-408, 2017 05 27.
Miller, P. S., Scott S., Masiulis S., De Colibus L., Pardon E., Steyaert J., and A Aricescu R., "Structural basis for GABA receptor potentiation by neurosteroids.", Nat Struct Mol Biol, vol. 24, issue 11, pp. 986-992, 2017 Nov.
2016
Pedre, B., van Bergen L. A. H., Palló A., Rosado L. A., Dufe V. Tamu, Van Molle I., Wahni K., Erdogan H., Alonso M., De Proft F., et al., "The active site architecture in peroxiredoxins: a case study on Mycobacterium tuberculosis AhpE.", Chem Commun (Camb), vol. 52, issue 67, pp. 10293-6, 2016 Aug 11.
Devree, B. T., Mahoney J. P., Vélez-Ruiz G. A., Rasmussen S. G. F., Kuszak A. J., Edwald E., Fung J-J., Manglik A., Masureel M., Du Y., et al., "Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.", Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.
Staus, D. P., Strachan R. T., Manglik A., Pani B., Kahsai A. W., Kim T. Hun, Wingler L. M., Ahn S., Chatterjee A., Masoudi A., et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
Pancsa, R., and Tompa P., "Coding Regions of Intrinsic Disorder Accommodate Parallel Functions.", Trends Biochem Sci, vol. 41, issue 11, pp. 898-906, 2016 Nov.
Jiang, X., Smirnova I., Kasho V., Wu J., Hirata K., Ke M., Pardon E., Steyaert J., Yan N., and H Kaback R., "Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.", Proc Natl Acad Sci U S A, vol. 113, issue 44, pp. 12420-12425, 2016 11 01.
Cho, K. Joon, Schepens B., Moonens K., Deng L., Fiers W., Remaut H., and Saelens X., "Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody.", J Virol, vol. 90, issue 1, pp. 611-5, 2016 01 01.
Javaheri, A., Kruse T., Moonens K., Mejías-Luque R., Debraekeleer A., Asche C. I., Tegtmeyer N., Kalali B., Bach N. C., Sieber S. A., et al., "Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.", Nat Microbiol, vol. 2, pp. 16189, 2016 Oct 17.
Fischer, B., Lüthy K., Paesmans J., De Koninck C., Maes I., Swerts J., Kuenen S., Uytterhoeven V., Verstreken P., and Versées W., "Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.", Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
Pancsa, R., Varadi M., Tompa P., and Vranken W. F., "Start2Fold: a database of hydrogen/deuterium exchange data on protein folding and stability.", Nucleic Acids Res, vol. 44, issue D1, pp. D429-34, 2016 Jan 04.
Zorzini, V., Mernik A., Lah J., Sterckx Y. G. J., De Jonge N., Garcia-Pino A., De Greve H., Versées W., and Loris R., "Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.", J Biol Chem, vol. 291, issue 21, pp. 10950-60, 2016 May 20.
Guharoy, M., Bhowmick P., Sallam M., and Tompa P., "Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.", Nat Commun, vol. 7, pp. 10239, 2016 Jan 06.
2015
Bhowmick, P., Guharoy M., and Tompa P., "Bioinformatics Approaches for Predicting Disordered Protein Motifs.", Adv Exp Med Biol, vol. 870, pp. 291-318, 2015.
Newman, J. A., Savitsky P., Allerston C. K., Bizard A. H., Özer Ö., Sarlós K., Liu Y., Pardon E., Steyaert J., Hickson I. D., et al., "Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.", Nucleic Acids Res, vol. 43, issue 10, pp. 5221-35, 2015 May 26.
Varadi, M., Guharoy M., Zsolyomi F., and Tompa P., "DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder.", BMC Bioinformatics, vol. 16, pp. 153, 2015 May 13.
Tusnády, G. E., Dobson L., and Tompa P., "Disordered regions in transmembrane proteins.", Biochim Biophys Acta, vol. 1848, issue 11 Pt A, pp. 2839-48, 2015 Nov.
Borysik, A. J., Kovacs D., Guharoy M., and Tompa P., "Ensemble Methods Enable a New Definition for the Solution to Gas-Phase Transfer of Intrinsically Disordered Proteins.", J Am Chem Soc, vol. 137, issue 43, pp. 13807-17, 2015 Nov 04.
Varadi, M., Zsolyomi F., Guharoy M., and Tompa P., "Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins.", PLoS One, vol. 10, issue 10, pp. e0139731, 2015.
Mackinnon, S. S., and Wodak S. J., "Landscape of intertwined associations in multi-domain homo-oligomeric proteins.", J Mol Biol, vol. 427, issue 2, pp. 350-70, 2015 Jan 30.
Sounier, R., Mas C., Steyaert J., Laeremans T., Manglik A., Huang W., Kobilka B. K., Déméné H., and Granier S., "Propagation of conformational changes during μ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 375-8, 2015 Aug 20.

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