Publications

Found 1249 results
2019
Boeynaems, S., A. S. Holehouse, V. Weinhardt, D. Kovacs, J. Van Lindt, C. Larabell, L. Van Den Bosch, R. Das, P. S. Tompa, R. V. Pappu, et al., "Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties.", Proc Natl Acad Sci U S A, vol. 116, issue 16, pp. 7889-7898, 2019 Apr 16.
Abskharon, R., F. Wang, A. Wohlkonig, J. Ruan, S. Soror, G. Giachin, E. Pardon, W. Zou, G. Legname, J. Ma, et al., "Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.", PLoS Pathog, vol. 15, issue 12, pp. e1008139, 2019 Dec.
Deyaert, E., M. Leemans, R. Kumar Singh, R. Gallardo, J. Steyaert, A. Kortholt, J. Lauer, and W. Versées, "Structure and nucleotide-induced conformational dynamics of the Roco protein.", Biochem J, vol. 476, issue 1, pp. 51-66, 2019 01 07.
Nguyen, A. H., A. R. B. Thomsen, T. J. Cahill, R. Huang, L-Y. Huang, T. Marcink, O. B. Clarke, S. Heissel, A. Masoudi, D. Ben-Hail, et al., "Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex.", Nat Struct Mol Biol, vol. 26, issue 12, pp. 1123-1131, 2019 Dec.
Lüthy, K., D. Mei, B. Fischer, M. De Fusco, J. Swerts, J. Paesmans, E. Parrini, N. Lubarr, I. A. Meijer, K. M. Mackenzie, et al., "TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model.", Brain, vol. 142, issue 8, pp. 2319-2335, 2019 Aug 01.
De Bruyn, P., S. Hadži, A. Vandervelde, A. Konijnenberg, M. Prolič-Kalinšek, Y. G. - J. Sterckx, F. Sobott, J. Lah, L. Van Melderen, and R. Loris, "Thermodynamic Stability of the Transcription Regulator PaaR2 from Escherichia coli O157:H7.", Biophys J, vol. 116, issue 8, pp. 1420-1431, 2019 Apr 23.
Yoon, J. H., A. V. Kulesha, Z. Lengyel-Zhand, A. N. Volkov, J. J. Rempillo, A. D'Souza, C. Costeas, C. Chester, E. R. Caselle, and O. V. Makhlynets, "Uno Ferro, a de novo Designed Protein, Binds Transition Metals with High Affinity and Stabilizes Semiquinone Radical Anion.", Chemistry, vol. 25, issue 67, pp. 15252-15256, 2019 Dec 02.
2018
Moonens, K., Y. Hamway, M. Neddermann, M. Reschke, N. Tegtmeyer, T. Kruse, R. Kammerer, R. Mejías-Luque, B. B. Singer, S. Backert, et al., " adhesin HopQ disrupts dimerization in human CEACAMs.", EMBO J, vol. 37, issue 13, 2018 Jul 02.
Varadi, M., G. De Baets, W. F. Vranken, P. Tompa, and R. Pancsa, "AmyPro: a database of proteins with validated amyloidogenic regions.", Nucleic Acids Res, vol. 46, issue D1, pp. D387-D392, 2018 Jan 04.
Köhler, M., C. Neff, C. Perez, C. Brunner, E. Pardon, J. Steyaert, G. Schneider, K. P. Locher, and R. Zenobi, "Binding Specificities of Nanobody•Membrane Protein Complexes Obtained from Chemical Cross-Linking and High-Mass MALDI Mass Spectrometry.", Anal Chem, vol. 90, issue 8, pp. 5306-5313, 2018 Apr 17.
Chevillard, F., H. Rimmer, C. Betti, E. Pardon, S. Ballet, N. van Hilten, J. Steyaert, W. E. Diederich, and P. Kolb, "Binding-Site Compatible Fragment Growing Applied to the Design of β-Adrenergic Receptor Ligands.", J Med Chem, vol. 61, issue 3, pp. 1118-1129, 2018 Feb 08.
Wauters, L., S. Terheyden, B. K. Gilsbach, M. Leemans, P. S. Athanasopoulos, G. Guaitoli, A. Wittinghofer, C. Johannes Gloeckner, W. Versées, and A. Kortholt, "Biochemical and kinetic properties of the complex Roco G-protein cycle.", Biol Chem, vol. 399, issue 12, pp. 1447-1456, 2018 11 27.
Bekesi, A., S. Abdellaoui, N. Holroyd, W. Van Delm, E. Pardon, J. Pauwels, K. Gevaert, J. Steyaert, S. Derveaux, A. Borysik, et al., "Challenges in the Structural-Functional Characterization of Multidomain, Partially Disordered Proteins CBP and p300: Preparing Native Proteins and Developing Nanobody Tools.", Methods Enzymol, vol. 611, pp. 607-675, 2018.
Kieken, F., K. Loth, N. van Nuland, P. Tompa, and T. Lenaerts, "Chemical shift assignments of the partially deuterated Fyn SH2-SH3 domain.", Biomol NMR Assign, vol. 12, issue 1, pp. 117-122, 2018 Apr.
Reyes, A. M., B. Pedre, M. Inés De Armas, M-A. Tossounian, R. Radi, J. Messens, and M. Trujillo, "Chemistry and Redox Biology of Mycothiol.", Antioxid Redox Signal, vol. 28, issue 6, pp. 487-504, 2018 02 20.
Pancsa, R., F. Zsolyomi, and P. Tompa, "Co-Evolution of Intrinsically Disordered Proteins with Folded Partners Witnessed by Evolutionary Couplings.", Int J Mol Sci, vol. 19, issue 11, 2018 Oct 25.
Necci, M., D. Piovesan, Z. Dosztányi, P. Tompa, and S. C. E. Tosatto, "A comprehensive assessment of long intrinsic protein disorder from the DisProt database.", Bioinformatics, vol. 34, issue 3, pp. 445-452, 2018 02 01.
Joncour, A., N. Desroy, C. Housseman, X. Bock, N. Bienvenu, L. Cherel, V. Labeguere, C. Peixoto, D. Annoot, L. Lepissier, et al., "Correction to Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2- a]pyridine Series of Autotaxin Inhibitors.", J Med Chem, vol. 61, issue 9, pp. 4270, 2018 May 10.
Kumar, H., J. S. Finer-Moore, X. Jiang, I. Smirnova, V. Kasho, E. Pardon, J. Steyaert, R. H Kaback, and R. M. Stroud, "Crystal Structure of a ligand-bound LacY-Nanobody Complex.", Proc Natl Acad Sci U S A, vol. 115, issue 35, pp. 8769-8774, 2018 08 28.
Monté, D., B. Clantin, F. Dewitte, Z. Lens, P. Rucktooa, E. Pardon, J. Steyaert, A. Verger, and V. Villeret, "Crystal structure of human Mediator subunit MED23.", Nat Commun, vol. 9, issue 1, pp. 3389, 2018 Aug 23.
Guharoy, M., T. Lazar, and P. Tompa, "Disordered Substrates of the 20S Proteasome Link Degradation with Phase Separation.", Proteomics, pp. e1800276, 2018 Aug 02.
Tossounian, M-A., I. Van Molle, K. Wahni, S. Jacques, K. Gevaert, F. Van Breusegem, D. Vertommen, D. Young, L. Astolfi Rosado, and J. Messens, "Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.", Biochim Biophys Acta Gen Subj, vol. 1862, issue 3, pp. 775-789, 2018 Mar.
Goemans, C. V., F. Beaufay, K. Wahni, I. Van Molle, J. Messens, and J-F. Collet, "An essential thioredoxin is involved in the control of the cell cycle in the bacterium .", J Biol Chem, vol. 293, issue 10, pp. 3839-3848, 2018 Mar 09.
Debraekeleer, A., and H. Remaut, "Future perspective for potential Helicobacter pylori eradication therapies.", Future Microbiol, vol. 13, pp. 671-687, 2018 05.
Stoeber, M., D. Jullié, B. T. Lobingier, T. Laeremans, J. Steyaert, P. W. Schiller, A. Manglik, and M. von Zastrow, "A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action.", Neuron, vol. 98, issue 5, pp. 963-976.e5, 2018 Jun 06.

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