Publications
Found 55 results
Filters: Author is De Baetselier, Patrick [Clear All Filters]
"Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.",
Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
"Interferon-gamma and nitric oxide in combination with antibodies are key protective host immune factors during trypanosoma congolense Tc13 Infections.",
J Infect Dis, vol. 193, issue 11, pp. 1575-83, 2006 Jun 1.
"Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response.",
Infect Immun, vol. 74, issue 11, pp. 6324-30, 2006 Nov.
"Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment.",
Int J Parasitol, vol. 36, issue 9, pp. 1025-35, 2006 Aug.
"The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent.",
J Immunol, vol. 175, issue 4, pp. 2501-9, 2005 Aug 15.
"Nanobodies as novel agents for cancer therapy.",
Expert Opin Biol Ther, vol. 5, issue 1, pp. 111-24, 2005 Jan.
"Efficient cancer therapy with a nanobody-based conjugate.",
Cancer Res, vol. 64, issue 8, pp. 2853-7, 2004 Apr 15.
"Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.",
J Biol Chem, vol. 279, issue 2, pp. 1256-61, 2004 Jan 9.
"Functional convergence of invertebrate and vertebrate cytokine-like molecules based on a similar lectin-like activity.",
Prog Mol Subcell Biol, vol. 34, pp. 145-63, 2004.
"P75 tumor necrosis factor-receptor shedding occurs as a protective host response during African trypanosomiasis.",
J Infect Dis, vol. 189, issue 3, pp. 527-39, 2004 Feb 1.
"Control of experimental Trypanosoma brucei infections occurs independently of lymphotoxin-alpha induction.",
Infect Immun, vol. 70, issue 3, pp. 1342-51, 2002 Mar.
"Efficient tumor targeting by single-domain antibody fragments of camels.",
Int J Cancer, vol. 98, issue 3, pp. 456-62, 2002 Mar 20.
"Selective pressure can influence the resistance of Trypanosoma congolense to normal human serum.",
Exp Parasitol, vol. 102, issue 2, pp. 61-5, 2002 Oct.
"The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense.",
Am J Trop Med Hyg, vol. 67, issue 6, pp. 684-90, 2002 Dec.
"VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology.",
Microbes Infect, vol. 4, issue 9, pp. 999-1006, 2002 Jul.
"A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.",
J Biol Chem, vol. 276, issue 36, pp. 33458-64, 2001 Sep 7.
"Trypanosoma brucei brucei infection impairs MHC class II antigen presentation capacity of macrophages.",
Parasite Immunol, vol. 22, issue 7, pp. 361-70, 2000 Jul.
"Convergent evolution of cytokines.",
Nature, vol. 400, issue 6745, pp. 627-8, 1999 Aug 12.
"Hemozoin is a key factor in the induction of malaria-associated immunosuppression.",
Parasite Immunol, vol. 21, issue 11, pp. 545-54, 1999 Nov.
"Tumor necrosis factor alpha is a key mediator in the regulation of experimental Trypanosoma brucei infections.",
Infect Immun, vol. 67, issue 6, pp. 3128-32, 1999 Jun.
"The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors.",
J Immunol, vol. 160, issue 4, pp. 1949-56, 1998 Feb 15.
"Isolation and characterization of single-chain Fv genes encoding antibodies specific for Drosophila Poxn protein.",
FEBS Lett, vol. 437, issue 1-2, pp. 75-80, 1998 Oct 16.
"The regulated expression of an intrabody produces a mutant phenotype in Drosophila.",
FEBS Lett, vol. 437, issue 1-2, pp. 81-6, 1998 Oct 16.
"Trypanosoma brucei infection elicits nitric oxide-dependent and nitric oxide-independent suppressive mechanisms.",
J Leukoc Biol, vol. 63, issue 4, pp. 429-39, 1998 Apr.
"Generation of a mouse tumor necrosis factor mutant with antiperitonitis and desensitization activities comparable to those of the wild type but with reduced systemic toxicity.",
Infect Immun, vol. 65, issue 6, pp. 2006-10, 1997 Jun.