Publications

Found 199 results
Filters: Keyword is Crystallography, X-Ray  [Clear All Filters]
2015
Moonens, K., I. Van den Broeck, M. De Kerpel, F. Deboeck, H. Raymaekers, H. Remaut, and H. De Greve, "Structural and functional insight into the carbohydrate receptor binding of F4 fimbriae-producing enterotoxigenic Escherichia coli.", J Biol Chem, vol. 290, issue 13, pp. 8409-19, 2015 Mar 27.
Moonens, K., I. Van den Broeck, E. Okello, E. Pardon, M. De Kerpel, H. Remaut, and H. De Greve, "Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.", Vet Res, vol. 46, pp. 14, 2015 Feb 24.
Huculeci, R., A. Garcia-Pino, L. Buts, T. Lenaerts, and N. van Nuland, "Structural insights into the intertwined dimer of fyn SH2.", Protein Sci, vol. 24, issue 12, pp. 1964-78, 2015 Dec.
Huang, W., A. Manglik, A. J. Venkatakrishnan, T. Laeremans, E. N. Feinberg, A. L. Sanborn, H. E. Kato, K. E. Livingston, T. S. Thorsen, R. C. Kling, et al., "Structural insights into µ-opioid receptor activation.", Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.
Rostislavleva, K., N. Soler, Y. Ohashi, L. Zhang, E. Pardon, J. E. Burke, G. R. Masson, C. Johnson, J. Steyaert, N. T. Ktistakis, et al., "Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.", Science, vol. 350, issue 6257, pp. aac7365, 2015 Oct 09.
Geertsma, E. R., Y-N. Chang, F. R. Shaik, Y. Neldner, E. Pardon, J. Steyaert, and R. Dutzler, "Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.", Nat Struct Mol Biol, vol. 22, issue 10, pp. 803-8, 2015 Oct.
2014
Ehrnstorfer, I. A., E. R. Geertsma, E. Pardon, J. Steyaert, and R. Dutzler, "Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.", Nat Struct Mol Biol, vol. 21, issue 11, pp. 990-6, 2014 Nov.
Sterckx, Y. G. J., S. Haesaerts, L. Van Melderen, and R. Loris, "Crystallization and preliminary X-ray analysis of two variants of the Escherichia coli O157 ParE2-PaaA2 toxin-antitoxin complex.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 9, pp. 1284-91, 2014 Sep.
Subedi, S., K. Moonens, E. Romão, A. Lo, G. Vandenbussche, J. Bugaytsova, S. Muyldermans, T. Borén, and H. Remaut, "Expression, purification and X-ray crystallographic analysis of the Helicobacter pylori blood group antigen-binding adhesin BabA.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 12, pp. 1631-5, 2014 Dec 01.
Oyen, D., J. Steyaert, and J. N. Barlow, "Inhibition of ligand exchange kinetics via active-site trapping with an antibody fragment.", Biochemistry, vol. 53, issue 12, pp. 1879-81, 2014 Apr 01.
De Gieter, S., A. Konijnenberg, A. Talavera, A. Butterer, S. Haesaerts, H. De Greve, F. Sobott, R. Loris, and A. Garcia-Pino, "The intrinsically disordered domain of the antitoxin Phd chaperones the toxin Doc against irreversible inactivation and misfolding.", J Biol Chem, vol. 289, issue 49, pp. 34013-23, 2014 Dec 05.
Garcia-Pino, A., N. Zenkin, and R. Loris, "The many faces of Fic: structural and functional aspects of Fic enzymes.", Trends Biochem Sci, vol. 39, issue 3, pp. 121-9, 2014 Mar.
Meusch, D., C. Gatsogiannis, R. G. Efremov, A. E. Lang, O. Hofnagel, I. R. Vetter, K. Aktories, and S. Raunser, "Mechanism of Tc toxin action revealed in molecular detail.", Nature, vol. 508, issue 7494, pp. 61-5, 2014 Apr 03.
Lo, A. W. H., K. Moonens, M. De Kerpel, L. Brys, E. Pardon, H. Remaut, and H. De Greve, "The molecular mechanism of Shiga toxin Stx2e neutralization by a single-domain antibody targeting the cell receptor-binding domain.", J Biol Chem, vol. 289, issue 36, pp. 25374-81, 2014 Sep 05.
Abskharon, R. N. N., G. Giachin, A. Wohlkonig, S. H. Soror, E. Pardon, G. Legname, and J. Steyaert, "Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody.", J Am Chem Soc, vol. 136, issue 3, pp. 937-44, 2014 Jan 22.
Goyal, P., P. V. Krasteva, N. Van Gerven, F. Gubellini, I. Van den Broeck, A. Troupiotis-Tsaïlaki, W. Jonckheere, G. Péhau-Arnaudet, J. S. Pinkner, M. R. Chapman, et al., "Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG.", Nature, vol. 516, issue 7530, pp. 250-3, 2014 Dec 11.
M Ceregido, A., M. Spínola Amilibia, L. Buts, J. Rivera-Torres, A. Garcia-Pino, J. Bravo, and N. A. J. van Nuland, "The structure of TAX1BP1 UBZ1+2 provides insight into target specificity and adaptability.", J Mol Biol, vol. 426, issue 3, pp. 674-90, 2014 Feb 06.
2013
Rocaboy, M., R. Herman, E. Sauvage, H. Remaut, K. Moonens, M. Terrak, P. Charlier, and F. Kerff, "The crystal structure of the cell division amidase AmiC reveals the fold of the AMIN domain, a new peptidoglycan binding domain.", Mol Microbiol, vol. 90, issue 2, pp. 267-77, 2013 Oct.
Goyal, P., N. Van Gerven, W. Jonckheere, and H. Remaut, "Crystallization and preliminary X-ray crystallographic analysis of the curli transporter CsgG.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 12, pp. 1349-53, 2013 Dec.
Volkov, A., A. Wohlkonig, S. H. Soror, and N. A. J. van Nuland, "Expression, purification, characterization, and solution nuclear magnetic resonance study of highly deuterated yeast cytochrome C peroxidase with enhanced solubility.", Biochemistry, vol. 52, issue 13, pp. 2165-75, 2013 Apr 2.
Oyen, D., R. Wechselberger, V. Srinivasan, J. Steyaert, and J. N. Barlow, "Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihydrofolate reductase of Escherichia coli.", Biochim Biophys Acta, vol. 1834, issue 10, pp. 2147-57, 2013 Oct.
De Genst, E., P-H. Chan, E. Pardon, S-T. D. Hsu, J. R. Kumita, J. Christodoulou, L. Menzer, D. Y. Chirgadze, C. V. Robinson, S. Muyldermans, et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
Löw, C., Y. Hoe Yau, E. Pardon, C. Jegerschöld, L. Wåhlin, E. M. Quistgaard, P. Moberg, S. Geifman-Shochat, J. Steyaert, and P. Nordlund, "Nanobody mediated crystallization of an archeal mechanosensitive channel.", PLoS One, vol. 8, issue 10, pp. e77984, 2013.
Van Laer, K., A. M. Dziewulska, M. Fislage, K. Wahni, A. Hbeddou, J-F. Collet, W. Versées, L. M. Mateos, V. Tamu Dufe, and J. Messens, "NrdH-redoxin of Mycobacterium tuberculosis and Corynebacterium glutamicum dimerizes at high protein concentration and exclusively receives electrons from thioredoxin reductase.", J Biol Chem, vol. 288, issue 11, pp. 7942-55, 2013 Mar 15.
Vuchelen, A., E. Pardon, J. Steyaert, B. Gamain, R. Loris, N. A. J. van Nuland, and S. Ramboarina, "Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 3, pp. 270-4, 2013 Mar 1.

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