Publications

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2017
Pauwels, K., P. Lebrun, and P. Tompa, "To be disordered or not to be disordered: is that still a question for proteins in the cell?", Cell Mol Life Sci, vol. 74, issue 17, pp. 3185-3204, 2017 09.
2016
Devree, B. T., J. P. Mahoney, G. A. Vélez-Ruiz, S. G. F. Rasmussen, A. J. Kuszak, E. Edwald, J-J. Fung, A. Manglik, M. Masureel, Y. Du, et al., "Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.", Nature, vol. 535, issue 7610, pp. 182-6, 2016 Jul 07.
Staus, D. P., R. T. Strachan, A. Manglik, B. Pani, A. W. Kahsai, T. Hun Kim, L. M. Wingler, S. Ahn, A. Chatterjee, A. Masoudi, et al., "Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.", Nature, vol. 535, issue 7612, pp. 448-52, 2016 Jul 21.
Odongo, S., Y. G. J. Sterckx, B. Stijlemans, D. Pillay, T. Baltz, S. Muyldermans, and S. Magez, "An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase.", PLoS Negl Trop Dis, vol. 10, issue 2, pp. e0004420, 2016 Feb.
Messens, J., "Bioplastic hydroxyl radical trapping.", Nat Chem Biol, vol. 12, issue 5, pp. 307-8, 2016 May.
Pancsa, R., and P. Tompa, "Coding Regions of Intrinsic Disorder Accommodate Parallel Functions.", Trends Biochem Sci, vol. 41, issue 11, pp. 898-906, 2016 Nov.
Vandervelde, A., R. Loris, J. Danckaert, and L. Gelens, "Computational Methods to Model Persistence.", Methods Mol Biol, vol. 1333, pp. 207-40, 2016.
Hubin, E., B. Vanschoenwinkel, K. Broersen, P. P. De Deyn, N. Koedam, N. A. Van Nuland, and K. Pauwels, "Could ecosystem management provide a new framework for Alzheimer's disease?", Alzheimers Dement, vol. 12, issue 1, pp. 65-74.e1, 2016 Jan.
Cho, K. Joon, B. Schepens, K. Moonens, L. Deng, W. Fiers, H. Remaut, and X. Saelens, "Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody.", J Virol, vol. 90, issue 1, pp. 611-5, 2016 01 01.
Guharoy, M., P. Bhowmick, and P. Tompa, "Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.", J Biol Chem, vol. 291, issue 13, pp. 6723-31, 2016 Mar 25.
Peyrassol, X., T. Laeremans, M. Gouwy, V. Lahura, M. Debulpaep, J. Van Damme, J. Steyaert, M. Parmentier, and I. Langer, "Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor.", J Immunol, vol. 196, issue 6, pp. 2893-901, 2016 Mar 15.
Egea-Jimenez, A. Luis, R. Gallardo, A. Garcia-Pino, Y. Ivarsson, A. Maria Wawrzyniak, R. Kashyap, R. Loris, J. Schymkowitz, F. Rousseau, and P. Zimmermann, "Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.", Nat Commun, vol. 7, pp. 12101, 2016 07 08.
Javaheri, A., T. Kruse, K. Moonens, R. Mejías-Luque, A. Debraekeleer, C. I. Asche, N. Tegtmeyer, B. Kalali, N. C. Bach, S. A. Sieber, et al., "Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.", Nat Microbiol, vol. 2, pp. 16189, 2016 Oct 17.
Ismail, S., M-J. Gherardi, A. Froese, M. Zanoun, V. Gigoux, P. Clerc, F. Gaits-Iacovoni, J. Steyaert, V. O. Nikolaev, and D. Fourmy, "Internalized Receptor for Glucose-dependent Insulinotropic Peptide stimulates adenylyl cyclase on early endosomes.", Biochem Pharmacol, vol. 120, pp. 33-45, 2016 Nov 15.
Van der Henst, C., T. Scrignari, C. Maclachlan, and M. Blokesch, "An intracellular replication niche for Vibrio cholerae in the amoeba Acanthamoeba castellanii.", ISME J, vol. 10, issue 4, pp. 897-910, 2016 Apr.
Fislage, M., L. Wauters, and W. Versées, "Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.", Biopolymers, vol. 105, issue 8, pp. 568-79, 2016 Aug.
Piai, A., E. O. Calçada, T. Tarenzi, A. Del Grande, M. Varadi, P. Tompa, I. C. Felli, and R. Pierattelli, "Just a Flexible Linker? The Structural and Dynamic Properties of CBP-ID4 Revealed by NMR Spectroscopy.", Biophys J, vol. 110, issue 2, pp. 372-81, 2016 Jan 19.
Zhan, Y-A., R. Abskharon, Y. Li, J. Yuan, L. Zeng, J. Dang, M. Camacho Martinez, Z. Wang, J. Mikol, S. Lehmann, et al., "Quiescin-sulfhydryl oxidase inhibits prion formation .", Aging (Albany NY), vol. 8, issue 12, pp. 3419-3429, 2016 12 11.
Fischer, B., K. Lüthy, J. Paesmans, C. De Koninck, I. Maes, J. Swerts, S. Kuenen, V. Uytterhoeven, P. Verstreken, and W. Versées, "Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.", Nat Struct Mol Biol, vol. 23, issue 11, pp. 965-973, 2016 Nov.
Massa, S., N. Vikani, C. Betti, S. Ballet, S. Vanderhaegen, J. Steyaert, B. Descamps, C. Vanhove, A. Bunschoten, F. W. B. van Leeuwen, et al., "Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.", Contrast Media Mol Imaging, vol. 11, issue 5, pp. 328-339, 2016 09.
Brunner, J. D., S. Schenck, and R. Dutzler, "Structural basis for phospholipid scrambling in the TMEM16 family.", Curr Opin Struct Biol, vol. 39, pp. 61-70, 2016 08.
Moonens, K., P. Gideonsson, S. Subedi, J. Bugaytsova, E. Romão, M. Mendez, J. Nordén, M. Fallah, L. Rakhimova, A. Shevtsova, et al., "Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.", Cell Host Microbe, vol. 19, issue 1, pp. 55-66, 2016 Jan 13.
Blanchetot, C., N. De Jonge, A. Desmyter, N. Ongenae, E. Hofman, A. Klarenbeek, A. Sadi, A. Hultberg, A. Kretz-Rommel, S. Spinelli, et al., "Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.", J Biol Chem, vol. 291, issue 26, pp. 13846-54, 2016 Jun 24.
Guaitoli, G., F. Raimondi, B. K. Gilsbach, Y. Gómez-Llorente, E. Deyaert, F. Renzi, X. Li, A. Schaffner, P. Kumar Anku Jagtap, K. Boldt, et al., "Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.", Proc Natl Acad Sci U S A, vol. 113, issue 30, pp. E4357-66, 2016 07 26.
Guharoy, M., P. Bhowmick, M. Sallam, and P. Tompa, "Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.", Nat Commun, vol. 7, pp. 10239, 2016 Jan 06.

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