Publications

Found 60 results
Filters: Keyword is Single-Domain Antibodies  [Clear All Filters]
2014
Moonens, K., M. De Kerpel, A. Coddens, E. Cox, E. Pardon, H. Remaut, and H. De Greve, "Nanobody mediated inhibition of attachment of F18 Fimbriae expressing Escherichia coli.", PLoS One, vol. 9, issue 12, pp. e114691, 2014.
Bethuyne, J., S. De Gieter, O. Zwaenepoel, A. Garcia-Pino, K. Durinck, A. Verhelle, G. Hassanzadeh-Ghassabeh, F. Speleman, R. Loris, and J. Gettemans, "A nanobody modulates the p53 transcriptional program without perturbing its functional architecture.", Nucleic Acids Res, vol. 42, issue 20, pp. 12928-38, 2014 Nov 10.
De Meyer, T., S. Muyldermans, and A. Depicker, "Nanobody-based products as research and diagnostic tools.", Trends Biotechnol, vol. 32, issue 5, pp. 263-70, 2014 May.
Abskharon, R. N. N., G. Giachin, A. Wohlkonig, S. H. Soror, E. Pardon, G. Legname, and J. Steyaert, "Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody.", J Am Chem Soc, vol. 136, issue 3, pp. 937-44, 2014 Jan 22.
Triest, S., A. Wohlkonig, E. Pardon, and J. Steyaert, "Production, crystallization and preliminary X-ray diffraction of the Gαs α-helical domain in complex with a nanobody.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 11, pp. 1504-7, 2014 Nov.
Staus, D. P., L. M. Wingler, R. T. Strachan, S. G. F. Rasmussen, E. Pardon, S. Ahn, J. Steyaert, B. K. Kobilka, and R. J. Lefkowitz, "Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.", Mol Pharmacol, vol. 85, issue 3, pp. 472-81, 2014 Mar.
Cardoso, F. Miguel, L. Itatí Ibañez, S. Van den Hoecke, S. De Baets, A. Smet, K. Roose, B. Schepens, F. J. Descamps, W. Fiers, S. Muyldermans, et al., "Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge.", J Virol, vol. 88, issue 15, pp. 8278-96, 2014 Aug.
Chaikuad, A., T. Keates, C. Vincke, M. Kaufholz, M. Zenn, B. Zimmermann, C. Gutiérrez, R-G. Zhang, C. Hatzos-Skintges, A. Joachimiak, et al., "Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.", Biochem J, vol. 459, issue 1, pp. 59-69, 2014 Apr 1.
Ditlev, S. B., R. Florea, M. A. Nielsen, T. G. Theander, S. Magez, P. Boeuf, and A. Salanti, "Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.", PLoS One, vol. 9, issue 1, pp. e84981, 2014.
2013
Sohier, J. S., C. Laurent, A. Chevigné, E. Pardon, V. Srinivasan, U. Wernery, P. Lassaux, J. Steyaert, and M. Galleni, "Allosteric inhibition of VIM metallo-β-lactamases by a camelid nanobody.", Biochem J, vol. 450, issue 3, pp. 477-86, 2013 Mar 15.
De Vos, J., N. Devoogdt, T. Lahoutte, and S. Muyldermans, "Camelid single-domain antibody-fragment engineering for (pre)clinical in vivo molecular imaging applications: adjusting the bullet to its target.", Expert Opin Biol Ther, vol. 13, issue 8, pp. 1149-60, 2013 Aug.
Irannejad, R., J. C. Tomshine, J. R. Tomshine, M. Chevalier, J. P. Mahoney, J. Steyaert, S. G. F. Rasmussen, R. K. Sunahara, H. El-Samad, B. Huang, et al., "Conformational biosensors reveal GPCR signalling from endosomes.", Nature, vol. 495, issue 7442, pp. 534-8, 2013 Mar 28.
Behdani, M., S. Zeinali, M. Karimipour, H. Khanahmad, S. Schoonooghe, A. Aslemarz, N. Seyed, R. Moazami-Godarzi, F. Baniahmad, M. Habibi-Anbouhi, et al., "Development of VEGFR2-specific Nanobody Pseudomonas exotoxin A conjugated to provide efficient inhibition of tumor cell growth.", N Biotechnol, vol. 30, issue 2, pp. 205-9, 2013 Jan 25.
Vercruysse, T., E. Boons, T. Venken, E. Vanstreels, A. Voet, J. Steyaert, M. De Maeyer, and D. Daelemans, "Mapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein Rev.", PLoS One, vol. 8, issue 4, pp. e60259, 2013.
Oyen, D., R. Wechselberger, V. Srinivasan, J. Steyaert, and J. N. Barlow, "Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihydrofolate reductase of Escherichia coli.", Biochim Biophys Acta, vol. 1834, issue 10, pp. 2147-57, 2013 Oct.
Hassanzadeh-Ghassabeh, G., N. Devoogdt, P. De Pauw, C. Vincke, and S. Muyldermans, "Nanobodies and their potential applications.", Nanomedicine (Lond), vol. 8, issue 6, pp. 1013-26, 2013 Jun.
Muyldermans, S., "Nanobodies: natural single-domain antibodies.", Annu Rev Biochem, vol. 82, pp. 775-97, 2013.
Guilliams, T., F. El-Turk, A. K. Buell, E. M. O'Day, F. A. Aprile, E. K. Esbjörner, M. Vendruscolo, N. Cremades, E. Pardon, L. Wyns, et al., "Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages.", J Mol Biol, vol. 425, issue 14, pp. 2397-411, 2013 Jul 24.
De Genst, E., P-H. Chan, E. Pardon, S-T. D. Hsu, J. R. Kumita, J. Christodoulou, L. Menzer, D. Y. Chirgadze, C. V. Robinson, S. Muyldermans, et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
Löw, C., Y. Hoe Yau, E. Pardon, C. Jegerschöld, L. Wåhlin, E. M. Quistgaard, P. Moberg, S. Geifman-Shochat, J. Steyaert, and P. Nordlund, "Nanobody mediated crystallization of an archeal mechanosensitive channel.", PLoS One, vol. 8, issue 10, pp. e77984, 2013.
Nguyen-Duc, T., E. Peeters, S. Muyldermans, D. Charlier, and G. Hassanzadeh-Ghassabeh, "Nanobody(R)-based chromatin immunoprecipitation/micro-array analysis for genome-wide identification of transcription factor DNA binding sites.", Nucleic Acids Res, vol. 41, issue 5, pp. e59, 2013 Mar 1.
Unciti-Broceta, J. Diego, T. Del Castillo, M. Soriano, S. Magez, and J. A. Garcia-Salcedo, "Novel therapy based on camelid nanobodies.", Ther Deliv, vol. 4, issue 10, pp. 1321-36, 2013 Oct.
Vuchelen, A., E. Pardon, J. Steyaert, B. Gamain, R. Loris, N. A. J. van Nuland, and S. Ramboarina, "Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 3, pp. 270-4, 2013 Mar 1.
Vanderhaegen, S., M. Fislage, K. Domanska, W. Versées, E. Pardon, V. Bellotti, and J. Steyaert, "Structure of an early native-like intermediate of β2-microglobulin amyloidogenesis.", Protein Sci, vol. 22, issue 10, pp. 1349-57, 2013 Oct.
Ward, A. B., P. Szewczyk, V. Grimard, C-W. Lee, L. Martinez, R. Doshi, A. Caya, M. Villaluz, E. Pardon, C. Cregger, et al., "Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.", Proc Natl Acad Sci U S A, vol. 110, issue 33, pp. 13386-91, 2013 Aug 13.

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