Publications

Found 17 results
Filters: Keyword is Molecular Sequence Data and Author is Pardon, Els  [Clear All Filters]
2016
Wijckmans, E., M. Nys, S. Debaveye, M. Brams, E. Pardon, K. Willegems, D. Bertrand, J. Steyaert, R. G. Efremov, and C. Ulens, "Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.", PLoS One, vol. 11, issue 3, pp. e0151183, 2016.
2015
Geertsma, E. R., Y-N. Chang, F. R. Shaik, Y. Neldner, E. Pardon, J. Steyaert, and R. Dutzler, "Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.", Nat Struct Mol Biol, vol. 22, issue 10, pp. 803-8, 2015 Oct.
2014
Ehrnstorfer, I. A., E. R. Geertsma, E. Pardon, J. Steyaert, and R. Dutzler, "Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.", Nat Struct Mol Biol, vol. 21, issue 11, pp. 990-6, 2014 Nov.
Nunes-Silva, S., S. Gangnard, M. Vidal, A. Vuchelen, S. Dechavanne, S. Chan, E. Pardon, J. Steyaert, S. Ramboarina, A. Chêne, et al., "Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain.", Sci Rep, vol. 4, pp. 7373, 2014 Dec 09.
Lo, A. W. H., K. Moonens, M. De Kerpel, L. Brys, E. Pardon, H. Remaut, and H. De Greve, "The molecular mechanism of Shiga toxin Stx2e neutralization by a single-domain antibody targeting the cell receptor-binding domain.", J Biol Chem, vol. 289, issue 36, pp. 25374-81, 2014 Sep 05.
Staus, D. P., L. M. Wingler, R. T. Strachan, S. G. F. Rasmussen, E. Pardon, S. Ahn, J. Steyaert, B. K. Kobilka, and R. J. Lefkowitz, "Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.", Mol Pharmacol, vol. 85, issue 3, pp. 472-81, 2014 Mar.
2013
Sohier, J. S., C. Laurent, A. Chevigné, E. Pardon, V. Srinivasan, U. Wernery, P. Lassaux, J. Steyaert, and M. Galleni, "Allosteric inhibition of VIM metallo-β-lactamases by a camelid nanobody.", Biochem J, vol. 450, issue 3, pp. 477-86, 2013 Mar 15.
Vuchelen, A., E. Pardon, J. Steyaert, B. Gamain, R. Loris, N. A. J. van Nuland, and S. Ramboarina, "Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 69, issue Pt 3, pp. 270-4, 2013 Mar 1.
2012
Pellis, M., E. Pardon, K. Zolghadr, U. Rothbauer, C. Vincke, J. Kinne, I. Dierynck, K. Hertogs, H. Leonhardt, J. Messens, et al., "A bacterial-two-hybrid selection system for one-step isolation of intracellularly functional Nanobodies.", Arch Biochem Biophys, vol. 526, issue 2, pp. 114-23, 2012 Oct 15.
Park, Y-J., E. Pardon, M. Wu, J. Steyaert, and W. G. J. Hol, "Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody.", Nucleic Acids Res, vol. 40, issue 4, pp. 1828-40, 2012 Feb.
2011
Korotkov, K. V., T. L. Johnson, M. G. Jobling, J. Pruneda, E. Pardon, A. Héroux, S. Turley, J. Steyaert, R. K. Holmes, M. Sandkvist, et al., "Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.", PLoS Pathog, vol. 7, issue 9, pp. e1002228, 2011 Sep.
Wu, M., Y-J. Park, E. Pardon, S. Turley, A. Hayhurst, J. Deng, J. Steyaert, and W. G. J. Hol, "Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.", J Struct Biol, vol. 174, issue 1, pp. 124-36, 2011 Apr.
2010
Vercruysse, T., E. Pardon, E. Vanstreels, J. Steyaert, and D. Daelemans, "An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production.", J Biol Chem, vol. 285, issue 28, pp. 21768-80, 2010 Jul 9.
2009
Korotkov, K. V., E. Pardon, J. Steyaert, and W. G. J. Hol, "Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.", Structure, vol. 17, issue 2, pp. 255-65, 2009 Feb 13.
Lam, A. Y., E. Pardon, K. V. Korotkov, W. G. J. Hol, and J. Steyaert, "Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.", J Struct Biol, vol. 166, issue 1, pp. 8-15, 2009 Apr.
2008
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
2005
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.