Publications

Found 11 results
Filters: Keyword is Humans and Author is Dirk Saerens  [Clear All Filters]
2012
Govaert, J., M. Pellis, N. Deschacht, C. Vincke, K. Conrath, S. Muyldermans, and D. Saerens, "Dual beneficial effect of interloop disulfide bond for single domain antibody fragments.", J Biol Chem, vol. 287, issue 3, pp. 1970-9, 2012 Jan 13.
2011
Ben Abderrazek, R., C. Vincke, I. Hmila, D. Saerens, N. Abidi, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin.", Protein Eng Des Sel, vol. 24, issue 9, pp. 727-35, 2011 Sep.
Stijlemans, B., G. Caljon, S. Kumar A. Natesan, D. Saerens, K. Conrath, D. Pérez-Morga, J. N. Skepper, A. Nikolaou, L. Brys, E. Pays, et al., "High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.", PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
2010
Huang, L., S. Muyldermans, and D. Saerens, "Nanobodies®: proficient tools in diagnostics.", Expert Rev Mol Diagn, vol. 10, issue 6, pp. 777-85, 2010 Sep.
2009
Vincke, C., R. Loris, D. Saerens, S. Martinez-Rodriguez, S. Muyldermans, and K. Conrath, "General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.", J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
2008
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
Saerens, D., G. Hassanzade Ghassabeh, and S. Muyldermans, "Single-domain antibodies as building blocks for novel therapeutics.", Curr Opin Pharmacol, vol. 8, issue 5, pp. 600-8, 2008 Oct.
Hmila, I., B. Abderrazek R, D. Saerens, Z. Benlasfar, K. Conrath, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "VHH, bivalent domains and chimeric Heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI'.", Mol Immunol, vol. 45, issue 14, pp. 3847-56, 2008 Aug.
2005
Saerens, D., F. Frederix, G. Reekmans, K. Conrath, K. Jans, L. Brys, L. Huang, E. Bosmans, G. Maes, G. Borghs, et al., "Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing.", Anal Chem, vol. 77, issue 23, pp. 7547-55, 2005 Dec 1.
Huang, L., G. Reekmans, D. Saerens, J-M. Friedt, F. Frederix, L. Francis, S. Muyldermans, A. Campitelli, and C. Van Hoof, "Prostate-specific antigen immunosensing based on mixed self-assembled monolayers, camel antibodies and colloidal gold enhanced sandwich assays.", Biosens Bioelectron, vol. 21, issue 3, pp. 483-90, 2005 Sep 15.
2004
Saerens, D., J. Kinne, E. Bosmans, U. Wernery, S. Muyldermans, and K. Conrath, "Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.", J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.