Publications
Found 7 results
Filters: Author is Vandemeulebroucke, An [Clear All Filters]
"Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei.",
Biochemistry, vol. 49, issue 41, pp. 8999-9010, 2010 Oct 19.
"Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.",
Biochim Biophys Acta, vol. 1794, issue 6, pp. 953-60, 2009 Jun.
"A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.",
J Biol Chem, vol. 283, issue 32, pp. 22272-82, 2008 Aug 08.
"Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry.",
Biochemistry, vol. 45, issue 30, pp. 9307-18, 2006 Aug 01.
"Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage.",
J Biol Chem, vol. 280, issue 15, pp. 14799-802, 2005 Apr 15.
"Leaving group activation by aromatic stacking: an alternative to general acid catalysis.",
J Mol Biol, vol. 338, issue 1, pp. 1-6, 2004 Apr 16.
"Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release.",
Biochemistry, vol. 42, issue 44, pp. 12902-8, 2003 Nov 11.