Publications

Found 13 results
Filters: Author is De Genst, Erwin  [Clear All Filters]
2013
Guilliams, T., F. El-Turk, A. K. Buell, E. M. O'Day, F. A. Aprile, E. K. Esbjörner, M. Vendruscolo, N. Cremades, E. Pardon, L. Wyns, et al., "Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages.", J Mol Biol, vol. 425, issue 14, pp. 2397-411, 2013 Jul 24.
De Genst, E., P-H. Chan, E. Pardon, S-T. D. Hsu, J. R. Kumita, J. Christodoulou, L. Menzer, D. Y. Chirgadze, C. V. Robinson, S. Muyldermans, et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
2010
De Genst, E., T. Guilliams, J. Wellens, E. M. O'Day, C. A. Waudby, S. Meehan, M. Dumoulin, S-T. D. Hsu, N. Cremades, K. H. G. Verschueren, et al., "Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.", J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
2008
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
2006
De Genst, E., D. Saerens, S. Muyldermans, and K. Conrath, "Antibody repertoire development in camelids.", Dev Comp Immunol, vol. 30, issue 1-2, pp. 187-98, 2006.
De Genst, E., K. Silence, K. Decanniere, K. Conrath, R. Loris, J. Kinne, S. Muyldermans, and L. Wyns, "Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.", Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
2005
Dao-Thi, M-H., L. Van Melderen, E. De Genst, H. Afif, L. Buts, L. Wyns, and R. Loris, "Molecular basis of gyrase poisoning by the addiction toxin CcdB.", J Mol Biol, vol. 348, issue 5, pp. 1091-102, 2005 May 20.
De Genst, E., K. Silence, M. Arbabi Ghahroudi, K. Decanniere, R. Loris, J. Kinne, L. Wyns, and S. Muyldermans, "Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.", J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
2004
De Genst, E., F. Handelberg, A. Van Meirhaeghe, S. Vynck, R. Loris, L. Wyns, and S. Muyldermans, "Chemical basis for the affinity maturation of a camel single domain antibody.", J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
Dao-Thi, M-H., L. Van Melderen, E. De Genst, L. Buts, A. Ranquin, L. Wyns, and R. Loris, "Crystallization of CcdB in complex with a GyrA fragment.", Acta Crystallogr D Biol Crystallogr, vol. 60, issue Pt 6, pp. 1132-4, 2004 Jun.
2003
Buts, L., J. Bouckaert, E. De Genst, R. Loris, S. Oscarson, M. Lahmann, J. Messens, E. Brosens, L. Wyns, and H. De Greve, "The fimbrial adhesin F17-G of enterotoxigenic Escherichia coli has an immunoglobulin-like lectin domain that binds N-acetylglucosamine.", Mol Microbiol, vol. 49, issue 3, pp. 705-15, 2003 Aug.
Buts, L., R. Loris, E. De Genst, S. Oscarson, M. Lahmann, J. Messens, E. Brosens, L. Wyns, H. De Greve, and J. Bouckaert, "Solving the phase problem for carbohydrate-binding proteins using selenium derivatives of their ligands: a case study involving the bacterial F17-G adhesin.", Acta Crystallogr D Biol Crystallogr, vol. 59, issue Pt 6, pp. 1012-5, 2003 Jun.
2002
De Genst, E., D. Areskoug, K. Decanniere, S. Muyldermans, and K. Andersson, "Kinetic and affinity predictions of a protein-protein interaction using multivariate experimental design.", J Biol Chem, vol. 277, issue 33, pp. 29897-907, 2002 Aug 16.