Publications
Found 23 results
Filters: Author is Laeremans, Toon [Clear All Filters]
"A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action.",
Neuron, vol. 98, issue 5, pp. 963-976.e5, 2018 Jun 06.
"Nanobody-Enabled Reverse Pharmacology on G-Protein-Coupled Receptors.",
Angew Chem Int Ed Engl, vol. 57, issue 19, pp. 5292-5295, 2018 May 04.
"Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.",
J Biol Chem, vol. 291, issue 31, pp. 16292-306, 2016 Jul 29.
"Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor.",
J Immunol, vol. 196, issue 6, pp. 2893-901, 2016 Mar 15.
"DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loops.",
MAbs, vol. 8, issue 6, pp. 1126-35, 2016 Aug-Sep.
"Modular Integrated Secretory System Engineering in Pichia pastoris To Enhance G-Protein Coupled Receptor Expression.",
ACS Synth Biol, vol. 5, issue 10, pp. 1070-1075, 2016 10 21.
"Propagation of conformational changes during μ-opioid receptor activation.",
Nature, vol. 524, issue 7565, pp. 375-8, 2015 Aug 20.
"Structural insights into µ-opioid receptor activation.",
Nature, vol. 524, issue 7565, pp. 315-21, 2015 Aug 20.
"A general protocol for the generation of Nanobodies for structural biology.",
Nat Protoc, vol. 9, issue 3, pp. 674-93, 2014 Mar.
"Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.",
Acta Crystallogr D Biol Crystallogr, vol. 69, issue Pt 6, pp. 1124-37, 2013 Jun.
"Structure of a bacterial type IV secretion core complex at subnanometre resolution.",
EMBO J, vol. 32, issue 8, pp. 1195-204, 2013 Apr 17.
"Selection by phage display of single domain antibodies specific to antigens in their native conformation.",
Methods Mol Biol, vol. 911, pp. 81-104, 2012.
"A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth.",
Int J Cancer, vol. 129, issue 8, pp. 2013-24, 2011 Oct 15.
"Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology.",
Mol Cancer Ther, vol. 7, issue 8, pp. 2288-97, 2008 Aug.
"Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR Nanobodies.",
Cancer Immunol Immunother, vol. 56, issue 3, pp. 303-317, 2007 Mar.
"Crystal structure of the intrinsically flexible addiction antidote MazE.",
J Biol Chem, vol. 278, issue 30, pp. 28252-7, 2003 Jul 25.
"Identification of an ATP-binding cassette transporter for export of the O-antigen across the inner membrane in Rhizobium etli based on the genetic, functional, and structural analysis of an lps mutant deficient in O-antigen.",
J Biol Chem, vol. 276, issue 20, pp. 17190-8, 2001 May 18.
"Phaseolus vulgaris recognizes Azorhizobium caulinodans Nod factors with a variety of chemical substituents.",
Mol Plant Microbe Interact, vol. 12, issue 9, pp. 820-4, 1999 Sep.
"Genes essential for nod factor production and nodulation are located on a symbiotic amplicon (AMPRtrCFN299pc60) in Rhizobium tropici.",
J Bacteriol, vol. 180, issue 11, pp. 2866-74, 1998 Jun.
"Isolation and sequencing of a second Rhizobium tropici CFN299 genetic locus that contains genes homologous to amino acid sulphate activation genes.",
DNA Seq, vol. 9, issue 1, pp. 65-70, 1998 Mar.
"Functional redundancy of genes for sulphate activation enzymes in Rhizobium sp. BR816.",
Microbiology, vol. 143 ( Pt 12), pp. 3933-42, 1997 Dec.
"Isolation and characterization of Rhizobium tropici Nod factor sulfation genes.",
Mol Plant Microbe Interact, vol. 9, issue 6, pp. 492-500, 1996 Aug.
"Characterization of the recA gene from Pseudomonas fluorescens OE 28.3 and construction of a recA mutant.",
J Gen Microbiol, vol. 139, issue 1, pp. 49-57, 1993 Jan.