Found 356 results
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Somme, J., B. Van Laer, M. Roovers, J. Steyaert, W. Versées, and L. Droogmans, "Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.", RNA, vol. 20, issue 8, pp. 1257-71, 2014 Aug.
Ehrnstorfer, I. A., E. R. Geertsma, E. Pardon, J. Steyaert, and R. Dutzler, "Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.", Nat Struct Mol Biol, vol. 21, issue 11, pp. 990-6, 2014 Nov.
Pathare, G. Ramnath, I. Nagy, P. Śledź, D. J. Anderson, H-J. Zhou, E. Pardon, J. Steyaert, F. Förster, A. Bracher, and W. Baumeister, "Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11.", Proc Natl Acad Sci U S A, vol. 111, issue 8, pp. 2984-9, 2014 Feb 25.
Pardon, E., T. Laeremans, S. Triest, S. G. F. Rasmussen, A. Wohlkonig, A. Ruf, S. Muyldermans, W. G. J. Hol, B. K. Kobilka, and J. Steyaert, "A general protocol for the generation of Nanobodies for structural biology.", Nat Protoc, vol. 9, issue 3, pp. 674-93, 2014 Mar.
De Gieter, S., A. Konijnenberg, A. Talavera, A. Butterer, S. Haesaerts, H. De Greve, F. Sobott, R. Loris, and A. Garcia-Pino, "The intrinsically disordered domain of the antitoxin Phd chaperones the toxin Doc against irreversible inactivation and misfolding.", J Biol Chem, vol. 289, issue 49, pp. 34013-23, 2014 Dec 05.
Meusch, D., C. Gatsogiannis, R. G. Efremov, A. E. Lang, O. Hofnagel, I. R. Vetter, K. Aktories, and S. Raunser, "Mechanism of Tc toxin action revealed in molecular detail.", Nature, vol. 508, issue 7494, pp. 61-5, 2014 Apr 03.
Lo, A. W. H., K. Moonens, M. De Kerpel, L. Brys, E. Pardon, H. Remaut, and H. De Greve, "The molecular mechanism of Shiga toxin Stx2e neutralization by a single-domain antibody targeting the cell receptor-binding domain.", J Biol Chem, vol. 289, issue 36, pp. 25374-81, 2014 Sep 05.
Moonens, K., M. De Kerpel, A. Coddens, E. Cox, E. Pardon, H. Remaut, and H. De Greve, "Nanobody mediated inhibition of attachment of F18 Fimbriae expressing Escherichia coli.", PLoS One, vol. 9, issue 12, pp. e114691, 2014.
Bethuyne, J., S. De Gieter, O. Zwaenepoel, A. Garcia-Pino, K. Durinck, A. Verhelle, G. Hassanzadeh-Ghassabeh, F. Speleman, R. Loris, and J. Gettemans, "A nanobody modulates the p53 transcriptional program without perturbing its functional architecture.", Nucleic Acids Res, vol. 42, issue 20, pp. 12928-38, 2014 Nov 10.
Denoncin, K., D. Vertommen, I. S. Arts, C. V. Goemans, S. Rahuel-Clermont, J. Messens, and J-F. Collet, "A new role for Escherichia coli DsbC protein in protection against oxidative stress.", J Biol Chem, vol. 289, issue 18, pp. 12356-64, 2014 May 02.
Polyansky, A. A., A. O. Chugunov, P. E. Volynsky, N. A. Krylov, D. E. Nolde, and R. G. Efremov, "PREDDIMER: a web server for prediction of transmembrane helical dimers.", Bioinformatics, vol. 30, issue 6, pp. 889-90, 2014 Mar 15.
Abskharon, R. N. N., G. Giachin, A. Wohlkonig, S. H. Soror, E. Pardon, G. Legname, and J. Steyaert, "Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody.", J Am Chem Soc, vol. 136, issue 3, pp. 937-44, 2014 Jan 22.
Lensink, M. F., and S. J. Wodak, "Score_set: a CAPRI benchmark for scoring protein complexes.", Proteins, vol. 82, issue 11, pp. 3163-9, 2014 Nov.
Sterckx, Y. G. J., A. Volkov, W. F. Vranken, J. Kragelj, M. Ringkjøbi Jensen, L. Buts, A. Garcia-Pino, T. Jové, L. Van Melderen, M. Blackledge, et al., "Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2.", Structure, vol. 22, issue 6, pp. 854-65, 2014 Jun 10.
Zorzini, V., L. Buts, M. Sleutel, A. Garcia-Pino, A. Talavera, S. Haesaerts, H. De Greve, A. Cheung, N. A. J. van Nuland, and R. Loris, "Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics.", Nucleic Acids Res, vol. 42, issue 10, pp. 6709-25, 2014 Jun.
Goyal, P., P. V. Krasteva, N. Van Gerven, F. Gubellini, I. Van den Broeck, A. Troupiotis-Tsaïlaki, W. Jonckheere, G. Péhau-Arnaudet, J. S. Pinkner, M. R. Chapman, et al., "Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG.", Nature, vol. 516, issue 7530, pp. 250-3, 2014 Dec 11.
Vanwetswinkel, S., A. Volkov, Y. G. J. Sterckx, A. Garcia-Pino, L. Buts, W. F. Vranken, J. Bouckaert, R. Roy, L. Wyns, and N. A. J. van Nuland, "Study of the structural and dynamic effects in the FimH adhesin upon α-d-heptyl mannose binding.", J Med Chem, vol. 57, issue 4, pp. 1416-27, 2014 Feb 27.
Macossay-Castillo, M., S. Kosol, P. Tompa, and R. Pancsa, "Synonymous constraint elements show a tendency to encode intrinsically disordered protein segments.", PLoS Comput Biol, vol. 10, issue 5, pp. e1003607, 2014 May.
Hubin, E., N. A. J. van Nuland, K. Broersen, and K. Pauwels, "Transient dynamics of Aβ contribute to toxicity in Alzheimer's disease.", Cell Mol Life Sci, vol. 71, issue 18, pp. 3507-21, 2014 Sep.
Brunner, J. Denise, N. K. Lim, S. Schenck, A. Duerst, and R. Dutzler, "X-ray structure of a calcium-activated TMEM16 lipid scramblase.", Nature, vol. 516, issue 7530, pp. 207-12, 2014 Dec 11.