Publications

Found 70 results
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2012
Park, Y-J., E. Pardon, M. Wu, J. Steyaert, and W. G. J. Hol, "Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody.", Nucleic Acids Res, vol. 40, issue 4, pp. 1828-40, 2012 Feb.
Baranova, E., R. Fronzes, A. Garcia-Pino, N. Van Gerven, D. Papapostolou, G. Péhau-Arnaudet, E. Pardon, J. Steyaert, S. Howorka, and H. Remaut, "SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly.", Nature, vol. 487, issue 7405, pp. 119-22, 2012 Jul 5.
Park, Y-J., T. Budiarto, M. Wu, E. Pardon, J. Steyaert, and W. G. J. Hol, "The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.", Nucleic Acids Res, vol. 40, issue 14, pp. 6966-77, 2012 Aug.
2011
Domanska, K., S. Vanderhaegen, V. Srinivasan, E. Pardon, F. Dupeux, J. A. Marquez, S. Giorgetti, M. Stoppini, L. Wyns, V. Bellotti, et al., "Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic beta2-microglobulin variant.", Proc Natl Acad Sci U S A, vol. 108, issue 4, pp. 1314-9, 2011 Jan 25.
Abskharon, R. N. N., S. H. Soror, E. Pardon, H. El Hassan, G. Legname, J. Steyaert, and A. Wohlkonig, "Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes.", Protein Eng Des Sel, vol. 24, issue 9, pp. 737-41, 2011 Sep.
Rasmussen, S. G. F., B. T. Devree, Y. Zou, A. C. Kruse, K. Young Chung, T. Sun Kobilka, F. Sun Thian, P. Seok Chae, E. Pardon, D. Calinski, et al., "Crystal structure of the β2 adrenergic receptor-Gs protein complex.", Nature, vol. 477, issue 7366, pp. 549-55, 2011 Sep 29.
Vercruysse, T., S. Pawar, W. De Borggraeve, E. Pardon, G. N. Pavlakis, C. Pannecouque, J. Steyaert, J. Balzarini, and D. Daelemans, "Measuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluorescence resonance energy transfer.", RNA Biol, vol. 8, issue 2, pp. 316-24, 2011 Mar-Apr.
Korotkov, K. V., T. L. Johnson, M. G. Jobling, J. Pruneda, E. Pardon, A. Héroux, S. Turley, J. Steyaert, R. K. Holmes, M. Sandkvist, et al., "Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.", PLoS Pathog, vol. 7, issue 9, pp. e1002228, 2011 Sep.
Westfield, G. H., S. G. F. Rasmussen, M. Su, S. Dutta, B. T. Devree, K. Young Chung, D. Calinski, G. Velez-Ruiz, A. N. Oleskie, E. Pardon, et al., "Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex.", Proc Natl Acad Sci U S A, vol. 108, issue 38, pp. 16086-91, 2011 Sep 20.
Rasmussen, S. G. F., H-J. Choi, J. Jose Fung, E. Pardon, P. Casarosa, P. Seok Chae, B. T. Devree, D. M. Rosenbaum, F. Sun Thian, T. Sun Kobilka, et al., "Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.", Nature, vol. 469, issue 7329, pp. 175-80, 2011 Jan 13.
Wu, M., Y-J. Park, E. Pardon, S. Turley, A. Hayhurst, J. Deng, J. Steyaert, and W. G. J. Hol, "Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.", J Struct Biol, vol. 174, issue 1, pp. 124-36, 2011 Apr.
2010
Abskharon, R. N. N., S. H. Soror, E. Pardon, H. El Hassan, G. Legname, J. Steyaert, and A. Wohlkonig, "Crystallization and preliminary X-ray diffraction analysis of a specific VHH domain against mouse prion protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 66, issue Pt 12, pp. 1644-6, 2010 Dec 1.
Vercruysse, T., E. Pardon, E. Vanstreels, J. Steyaert, and D. Daelemans, "An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production.", J Biol Chem, vol. 285, issue 28, pp. 21768-80, 2010 Jul 9.
Ryckaert, S., E. Pardon, J. Steyaert, and N. Callewaert, "Isolation of antigen-binding camelid heavy chain antibody fragments (nanobodies) from an immune library displayed on the surface of Pichia pastoris.", J Biotechnol, vol. 145, issue 2, pp. 93-8, 2010 Jan 15.
De Genst, E., T. Guilliams, J. Wellens, E. M. O'Day, C. A. Waudby, S. Meehan, M. Dumoulin, S-T. D. Hsu, N. Cremades, K. H. G. Verschueren, et al., "Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.", J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
2009
Korotkov, K. V., E. Pardon, J. Steyaert, and W. G. J. Hol, "Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.", Structure, vol. 17, issue 2, pp. 255-65, 2009 Feb 13.
Lam, A. Y., E. Pardon, K. V. Korotkov, W. G. J. Hol, and J. Steyaert, "Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.", J Struct Biol, vol. 166, issue 1, pp. 8-15, 2009 Apr.
2008
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
2005
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
Dumoulin, M., D. Canet, A. M. Last, E. Pardon, D. B. Archer, S. Muyldermans, L. Wyns, A. Matagne, C. V. Robinson, C. Redfield, et al., "Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.", J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.

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